1VZX

Roles of active site tryptophans in substrate binding and catalysis by ALPHA-1,3 GALACTOSYLTRANSFERASE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE	polymer	289	34067.1	2	UniProt (P14769) Pfam (PF03414) In PDB	BOS TAURUS (BOVINE)	GALACTOSYLTRANSFERASE, UDP-GALACTOSE, BETA-D-GALACTOSYL-1,4-N-ACETYL-D-GLUCOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE
2	C, D	beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		383.3	2	In PDB GlyTouCan (G00055MO)
3	A, B	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
4	A, B	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	2	Chemie (UDP)
5	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6		water	water		18.0	642	Chemie (HOH)

Sequence modifications

A, B: 80 - 368 (UniProt: P14769)

PDB	External Database	Details
Tyr 314	Trp 314	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68134.3
Branched	Number of molecules	2
	Total formula weight	766.7
Non-Polymers*	Number of molecules	6
	Total formula weight	1102.4
All*	Total formula weight	70003.3

*Water molecules are not included.