1TOI
Hydrocinnamic acid-bound structure of Hexamutant + A293D mutant of E. coli aspartate aminotransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Aspartate aminotransferase | polymer | 396 | 43909.4 | 1 | UniProt (P00509) Pfam (PF00155) In PDB | Escherichia coli | Transaminase A, ASPAT |
| 2 | A | HYDROCINNAMIC ACID | non-polymer | 150.2 | 1 | Chemie (HCI) | |||
| 3 | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence modifications
A: 5 - 400 (UniProt: P00509)
| PDB | External Database | Details |
|---|---|---|
| Leu 39 | Val 35 | engineered mutation |
| Tyr 41 | Lys 37 | engineered mutation |
| Ile 47 | Thr 43 | engineered mutation |
| Leu 69 | Asn 64 | engineered mutation |
| Ser 109 | Thr 104 | engineered mutation |
| Llp 258 | Lys 246 | modified residue |
| Asp 293 | Ala 281 | engineered mutation |
| Ser 297 | Asn 285 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43909.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 150.2 | |
| All* | Total formula weight | 44059.6 |
