1SU5
Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Triosephosphate isomerase | polymer | 247 | 26550.2 | 2 | UniProt (P00940) Pfam (PF00121) In PDB | Gallus gallus (chicken) | TIM |
| 2 | A, B | 2-PHOSPHOGLYCOLIC ACID | non-polymer | 156.0 | 2 | Chemie (PGA) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 248 (UniProt: P00940)
| PDB | External Database | Details |
|---|---|---|
| Asn 174 | Lys 173 | engineered mutation |
| Pro 175 | Thr 174 | engineered mutation |
| Asn 176 | Ala 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53100.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1452.9 | |
| All* | Total formula weight | 54553.4 |
