1RWV
Crystal structure of human caspase-1 in complex with 5-[5-(1-carboxymethyl-2-oxo-propylcarbamoyl)-5-phenyl-pentylsulfamoyl]-2-hydroxy-benzoic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Interleukin-1 beta convertase | polymer | 178 | 19869.8 | 1 | UniProt (P29466) Pfam (PF00656) In PDB | Homo sapiens (human) | IL-1BC, IL-1 beta converting enzyme, ICE, Interleukin-1 beta converting enzyme, P45, Caspase-1, CASP-1 |
2 | B | Interleukin-1 beta convertase | polymer | 88 | 10258.8 | 1 | UniProt (P29466) Pfam (PF00656) In PDB | Homo sapiens (human) | IL-1BC, IL-1 beta converting enzyme, ICE, Interleukin-1 beta converting enzyme, P45, Caspase-1, CASP-1 |
3 | A | 5-[5-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-5-PHENYL-PENTYLSULFAMOYL]-2-HYDROXY-BENZOIC ACID | non-polymer | 520.6 | 1 | Chemie (5PH) | |||
4 | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 30128.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 520.6 | |
All* | Total formula weight | 30649.1 |