1RRK
Crystal Structure Analysis of the Bb segment of Factor B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Complement factor B | polymer | 497 | 56246.2 | 1 | UniProt (P00751) Pfam (PF00092) Pfam (PF00089) In PDB | Homo sapiens (human) | C3/C5 convertase, Properdin factor B, Glycine-rich beta glycoprotein, GBG, PBF2 |
| 2 | A | IODIDE ION | non-polymer | 126.9 | 2 | Chemie (IOD) | |||
| 3 | A | SODIUM ION | non-polymer | 23.0 | 7 | Chemie (NA) | |||
| 4 | A | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 5 | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
A: 243 - 739 (UniProt: P00751)
| PDB | External Database | Details |
|---|---|---|
| Val 267 | Cys 292 | engineered mutation |
| Cys 428 | Phe 453 | engineered mutation |
| Cys 435 | Asn 460 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56246.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 473.7 | |
| All* | Total formula weight | 56719.8 |
