1P6C
crystal structure of phosphotriesterase triple mutant H254G/H257W/L303T complexed with diisopropylmethylphosphonate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Parathion hydrolase | polymer | 336 | 36330.3 | 2 | UniProt (P0A433) Pfam (PF02126) In PDB | Flavobacterium sp. | Phosphotriesterase, PTE |
2 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | A, B | DIETHYL 4-METHYLBENZYLPHOSPHONATE | non-polymer | 242.3 | 2 | Chemie (EBP) | |||
4 | A, B | METHYLPHOSPHONIC ACID DIISOPROPYL ESTER | non-polymer | 180.2 | 2 | Chemie (DII) | |||
5 | water | water | 18.0 | 321 | Chemie (HOH) |
Sequence modifications
A, B: 30 - 365 (UniProt: P0A433)
PDB | External Database | Details |
---|---|---|
Gly 254 | His 254 | engineered mutation |
Trp 257 | His 257 | engineered mutation |
Thr 303 | Leu 303 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 72660.6 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1106.5 | |
All* | Total formula weight | 73767.1 |