1MH0
Crystal structure of the anticoagulant slow form of thrombin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Prothrombin | polymer | 287 | 33007.9 | 2 | UniProt (P00734) Pfam (PF09396) Pfam (PF00089) In PDB | Homo sapiens (human) | Alpha-thrombin; coagulation factor II |
2 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
3 | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 245 (UniProt: P00734)
PDB | External Database | Details |
---|---|---|
Ala 77 | Arg 436 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 66015.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 66458.2 |