1KNJ
Co-Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli Involved in Mevalonate-Independent Isoprenoid Biosynthesis, Complexed with CMP/MECDP/Mn2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | polymer | 159 | 17108.1 | 1 | UniProt (P62617) Pfam (PF02542) In PDB | Escherichia coli | MECPS |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | A | CYTIDINE-5'-MONOPHOSPHATE | non-polymer | 323.2 | 1 | Chemie (C5P) | |||
| 4 | A | 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE | non-polymer | 278.1 | 1 | Chemie (CDI) | |||
| 5 | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P62617)
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | Met 1 | MODIFIED RESIDUE |
| Mse 105 | Met 105 | MODIFIED RESIDUE |
| Mse 112 | Met 112 | MODIFIED RESIDUE |
| Mse 124 | Met 124 | MODIFIED RESIDUE |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17108.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 656.2 | |
| All* | Total formula weight | 17764.3 |
