1K6M
Crystal Structure of Human Liver 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2-phosphatase | polymer | 432 | 50195.0 | 2 | UniProt (P16118) Pfam (PF01591) Pfam (PF00300) In PDB | Homo sapiens (human) | |
| 2 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 3 | A, B | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 2 | Chemie (AGS) | |||
| 4 | water | water | 18.0 | 397 | Chemie (HOH) |
Sequence modifications
A, B: 39 - 470 (UniProt: P16118)
| PDB | External Database | Details |
|---|---|---|
| Phe 67 | Trp 68 | engineered mutation |
| Phe 301 | Trp 302 | engineered mutation |
| Phe 322 | Trp 323 | engineered mutation |
| Glu 409 | Asp 410 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100390.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1426.4 | |
| All* | Total formula weight | 101816.4 |
