1JWZ
Crystal structure of TEM-64 beta-lactamase in complex with a boronic acid inhibitor (105)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-lactamase TEM | polymer | 263 | 28841.9 | 1 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) In PDB | Escherichia coli | |
| 2 | A | N-[5-METHYL-3-O-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID AMIDE] BORONIC ACID | non-polymer | 294.5 | 1 | Chemie (105) | |||
| 3 | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A: 26 - 290 (UniProt: P62593)
| PDB | External Database | Details |
|---|---|---|
| Lys 104 | Glu 102 | engineered mutation |
| Ser 164 | Arg 162 | engineered mutation |
| Thr 182 | Met 180 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28841.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 294.5 | |
| All* | Total formula weight | 29136.4 |
