1J1D

Crystal structure of the 46kDa domain of human cardiac troponin in the Ca2+ saturated form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Troponin C	polymer	161	18401.4	2	UniProt (P63316) Pfam (PF13833) Pfam (PF13499) In PDB	Homo sapiens (human)	TNC
2	B, E	Troponin T	polymer	106	12842.8	2	UniProt (P45379) Pfam (PF00992) In PDB	Homo sapiens (human)	TnT
3	C, F	Troponin I	polymer	133	15191.7	2	UniProt (P19429) Pfam (PF00992) In PDB	Homo sapiens (human)	TNI
4	A, D	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)
5		water	water		18.0	102	Chemie (HOH)

Sequence modifications

A, D: 1 - 161 (UniProt: P63316)

PDB	External Database	Details
Ser 35	Cys 35	engineered mutation
Ser 84	Cys 84	engineered mutation

C, F: 31 - 163 (UniProt: P19429)

PDB	External Database	Details
Met 31	Thr 30	engineered mutation
Ala 80	Cys 79	engineered mutation
Ala 97	Cys 96	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	92871.7
Non-Polymers*	Number of molecules	6
	Total formula weight	240.5
All*	Total formula weight	93112.2

*Water molecules are not included.