1IJN
Crystal structure of the transthyretin mutant TTR C10A/Y114C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | TRANSTHYRETIN | polymer | 127 | 13685.3 | 2 | UniProt (P02766) Pfam (PF00576) In PDB | Homo sapiens (human) | TBPA, TTR, ATTR |
| 2 | A, B | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 6 | Chemie (BME) | |||
| 3 | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Ala 10 | Cys 30 | engineered mutation |
| Cys 114 | Tyr 134 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27370.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 468.8 | |
| All* | Total formula weight | 27839.3 |
