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1I7G

CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN FROM HUMAN PPAR-ALPHA IN COMPLEX WITH THE AGONIST AZ 242

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHApolymer28732337.31UniProt (Q07869)
Pfam (PF00104)
In PDB
Homo sapiens (human)PPAR-ALPHA
2ASODIUM IONnon-polymer23.01Chemie (NA)
3A(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL}ETHOXY)PHENYL]PROPANOIC ACIDnon-polymer408.51Chemie (AZ2)
4AN,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDEnon-polymer862.11Chemie (CPQ)
5waterwater18.070Chemie (HOH)
Sequence modifications
A: 196 - 468 (UniProt: Q07869)
PDBExternal DatabaseDetails
Gly 182-cloning artifact
Ser 183-cloning artifact
His 184-cloning artifact
Met 185-cloning artifact
Ser 186-cloning artifact
Gly 187-cloning artifact
Glu 188-cloning artifact
Asp 189-cloning artifact
Ser 190-cloning artifact
Glu 191-cloning artifact
Thr 192-cloning artifact
Glu 193-cloning artifact
Ala 194-cloning artifact
Asp 195-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32337.3
Non-Polymers*Number of molecules3
Total formula weight1293.5
All*Total formula weight33630.9
*Water molecules are not included.

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PDB entries from 2024-05-01

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