1FUY
CRYSTAL STRUCTURE OF BETAA169L/BETAC170W DOUBLE MUTANT OF TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUORO-INDOLE-PROPANOL PHOSPHATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TRYPTOPHAN SYNTHASE ALPHA CHAIN | polymer | 268 | 28698.8 | 1 | UniProt (P00929) Pfam (PF00290) In PDB | Salmonella typhimurium | |
| 2 | B | TRYPTOPHAN SYNTHASE BETA CHAIN | polymer | 396 | 42912.8 | 1 | UniProt (P0A2K1) Pfam (PF00291) In PDB | Salmonella typhimurium | |
| 3 | A | 5-FLUOROINDOLE PROPANOL PHOSPHATE | non-polymer | 273.2 | 1 | Chemie (FIP) | |||
| 4 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | B | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 6 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
B: 2 - 397 (UniProt: P0A2K1)
| PDB | External Database | Details |
|---|---|---|
| Ser 34 | Arg 33 | cloning artifact |
| Leu 169 | Ala 168 | engineered mutation |
| Trp 170 | Cys 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71611.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 543.3 | |
| All* | Total formula weight | 72155.0 |
