1FRP
CRYSTAL STRUCTURE OF FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH FRUCTOSE-2,6-BISPHOSPHATE, AMP AND ZN2+ AT 2.0 ANGSTROMS RESOLUTION. ASPECTS OF SYNERGISM BETWEEN INHIBITORS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | FRUCTOSE 1,6-BISPHOSPHATASE | polymer | 335 | 36487.0 | 2 | UniProt (P00636) Pfam (PF00316) Pfam (PF18913) In PDB | Sus scrofa (pig) | |
| 2 | A, B | 2,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 2 | Chemie (FDP) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A, B | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 5 | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 335 (UniProt: P00636)
| PDB | External Database | Details |
|---|---|---|
| Gln 20 | Glu 20 | conflict |
| Ala 62 | Ser 62 | conflict |
| Thr 96 | Ser 96 | conflict |
| Asn 199 | Asp 199 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72974.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1505.5 | |
| All* | Total formula weight | 74479.5 |
