1EET
HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH THE INHIBITOR MSC204
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HIV-1 REVERSE TRANSCRIPTASE | polymer | 557 | 64160.6 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | Human immunodeficiency virus 1 | |
| 2 | B | HIV-1 REVERSE TRANSCRIPTASE | polymer | 427 | 49927.4 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | Human immunodeficiency virus 1 | |
| 3 | A | 1-(5-BROMO-PYRIDIN-2-YL)-3-[2-(6-FLUORO-2-HYDROXY-3-PROPIONYL-PHENYL)-CYCLOPROPYL]-UREA | non-polymer | 422.2 | 1 | Chemie (BFU) | |||
| 4 | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A: 1 - 557 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Gln 478 | Glu 478 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114088.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 422.2 | |
| All* | Total formula weight | 114510.2 |
