1DH3

CRYSTAL STRUCTURE OF A CREB BZIP-CRE COMPLEX REVEALS THE BASIS FOR CREB FAIMLY SELECTIVE DIMERIZATION AND DNA BINDING

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, D	DNA (5'-D(*CP*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3')	polymer	21	6424.1	2
2	A, C	TRANSCRIPTION FACTOR CREB	polymer	55	6686.8	2	UniProt (Q01147) Pfam (PF00170) In PDB	Mus musculus (house mouse)
3	C	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4		water	water		18.0	17	Chemie (HOH)

Sequence modifications

A, C: 285 - 339 (UniProt: Q01147)

PDB	External Database	Details
Ser 300	Cys 216	engineered mutation
Ser 310	Cys 226	engineered mutation
Ser 300	Cys 253	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	26222.0
Non-Polymers*	Number of molecules	1
	Total formula weight	24.3
All*	Total formula weight	26246.3

*Water molecules are not included.