1CTE
CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | CATHEPSIN B | polymer | 254 | 27735.8 | 2 | UniProt (P00787) Pfam (PF00112) In PDB | Rattus norvegicus (Norway rat) | |
| 2 | A, B | 2-PYRIDINETHIOL | non-polymer | 111.2 | 2 | Chemie (PYS) | |||
| 3 | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 254 (UniProt: P00787)
| PDB | External Database | Details |
|---|---|---|
| Ala 115 | Ser 194 | CONFLICT |
| Ala 223 | Val 302 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55471.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 222.3 | |
| All* | Total formula weight | 55694.0 |
