1BDR

HIV-1 (2: 31, 33-37) PROTEASE COMPLEXED WITH INHIBITOR SB203386

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	HIV-1 PROTEASE	polymer	99	10669.6	2	UniProt (P04587) Pfam (PF00077) In PDB	Human immunodeficiency virus 1
2	B	(2R,4S,5S,1'S)-2-PHENYLMETHYL-4-HYDROXY-5-(TERT-BUTOXYCARBONYL)AMINO-6-PHENYL HEXANOYL-N-(1'-IMIDAZO-2-YL)-2'-METHYLPROPANAMIDE	non-polymer		534.7	1	Chemie (IM1)
3		water	water		18.0	56	Chemie (HOH)

Sequence modifications

A, B: 1 - 99 (UniProt: P04587)

PDB	External Database	Details
Ser 31	Thr 99	engineered mutation
Val 33	Leu 101	engineered mutation
Ala 34	Glu 102	conflict
Gly 35	Glu 103	engineered mutation
Ile 36	Met 104	engineered mutation
Glu 37	Ser 105	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21339.2
Non-Polymers*	Number of molecules	1
	Total formula weight	534.7
All*	Total formula weight	21873.9

*Water molecules are not included.