1AJ7
IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN) | polymer | 214 | 23465.0 | 1 | GenBank (4768677) | Mus musculus (house mouse) | |
| 2 | H | IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN) | polymer | 217 | 23062.8 | 1 | UniProt (P01857) Pfam (PF07654) In PDB | Homo sapiens (human) | |
| 3 | H | 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID | non-polymer | 302.2 | 1 | Chemie (NPE) |
Sequence modifications
L: 1 - 214 (GenBank: 4768677)
| PDB | External Database | Details |
|---|---|---|
| Leu 15 | Val 37 | conflict |
| Glu 17 | Asp 39 | conflict |
| Ser 20 | Thr 42 | conflict |
| Leu 21 | Ile 43 | conflict |
| Arg 24 | Gln 46 | conflict |
| Glu 28 | Asp 50 | conflict |
| Ser 30 | Asn 52 | conflict |
| Gly 31 | Asn 53 | conflict |
| Ser 34 | Asn 56 | conflict |
| Leu 36 | Tyr 58 | conflict |
| Asp 41 | Gly 63 | conflict |
| Gly 42 | Lys 64 | conflict |
| Ile 44 | Pro 66 | conflict |
| Arg 46 | Leu 68 | conflict |
| Ala 50 | Gly 72 | conflict |
| Thr 53 | Asn 75 | conflict |
| Asp 55 | Glu 77 | conflict |
| Ser 56 | Thr 78 | conflict |
| Lys 60 | Ser 82 | conflict |
| Arg 66 | Gly 88 | conflict |
| Ser 69 | Thr 91 | conflict |
| Tyr 71 | Phe 93 | conflict |
| Ser 72 | Ile 94 | conflict |
| Leu 73 | Phe 95 | conflict |
| Glu 79 | Gln 101 | conflict |
| Ser 80 | Pro 102 | conflict |
| Phe 83 | Ile 105 | conflict |
| Asp 85 | Thr 107 | conflict |
| Leu 89 | Gln 111 | conflict |
| Ala 92 | Asp 114 | conflict |
| Ser 93 | Asn 115 | conflict |
| Tyr 94 | Leu 116 | conflict |
| Arg 96 | Leu 118 | conflict |
| Ser 177 | Asn 199 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46527.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 302.2 | |
| All* | Total formula weight | 46829.9 |
