PDB: 15 resultsInfo pagesStatus searchChemie searchBIRD

---

6E2H	Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30 Descriptor: Protein dpy-30 homolog, Set1/Ash2 histone methyltransferase complex subunit ASH2 Authors: Joshi, M, Brunzelle, J.S, Couture, J.F. Deposit date: 2018-07-11 Release date: 2018-08-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.236 Å) Cite: Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation. Structure, 26, 2018
4RIQ	Crystal structure of DPY-30 dimerization/docking domain in complex with Ash2L Sdc1-DPY-30 Interacting region (SDI) Descriptor: Protein dpy-30 homolog, SULFATE ION, Set1/Ash2 histone methyltransferase complex subunit ASH2 Authors: Tremblay, V, Couture, J.-F. Deposit date: 2014-10-07 Release date: 2014-12-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.231 Å) Cite: Molecular Basis for DPY-30 Association to COMPASS-like and NURF Complexes. Structure, 22, 2014
3G36	Crystal structure of the human DPY-30-like C-terminal domain Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... Authors: Wang, X, Lou, Z, Bartlam, M, Rao, Z. Deposit date: 2009-02-02 Release date: 2009-06-30 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Crystal structure of the C-terminal domain of human DPY-30-like protein: A component of the histone methyltransferase complex J.Mol.Biol., 390, 2009
6PWV	Cryo-EM structure of MLL1 core complex bound to the nucleosome Descriptor: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... Authors: Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. Deposit date: 2019-07-23 Release date: 2019-12-18 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
7UD5	Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome Descriptor: 601 DNA (146-MER), Histone H2A, Histone H2B 1.1, ... Authors: Niklas, H.A, Rahman, S, Worden, E.J, Wolberger, C. Deposit date: 2022-03-18 Release date: 2022-09-21 Last modified: 2022-10-05 Method: ELECTRON MICROSCOPY (4.25 Å) Cite: Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome. Proc.Natl.Acad.Sci.USA, 119, 2022
4RT4	Crystal structure of Dpy30 complexed with Bre2 Descriptor: Peptide from COMPASS component BRE2, Protein dpy-30 homolog Authors: Zhang, H.M, Li, M, Chang, W.R. Deposit date: 2014-11-12 Release date: 2015-10-07 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.997 Å) Cite: Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation Protein Cell, 6, 2015
4RTA	Cystal structure of the Dpy30 for MLL/SET1 COMPASS H3K4 trimethylation Descriptor: FORMIC ACID, Protein dpy-30 homolog Authors: Zhang, H.M, Li, M, Chang, W.R. Deposit date: 2014-11-14 Release date: 2015-10-07 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.123 Å) Cite: Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation. Protein Cell, 6, 2015
5SXM	WDR5 in complex with MLL Win motif peptidomimetic Descriptor: ACE-ALA-ARG-THR-GLU-VAL-TYR-NH2, WD repeat-containing protein 5 Authors: Alicea-Velazquez, N.L, Shinsky, S.A, Cosgrove, M.S. Deposit date: 2016-08-09 Release date: 2016-09-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes. J.Biol.Chem., 291, 2016
3TOJ	Structure of the SPRY domain of human Ash2L Descriptor: Set1/Ash2 histone methyltransferase complex subunit ASH2 Authors: Chen, Y, Cao, F, Wan, B, Dou, Y, Lei, M. Deposit date: 2011-09-05 Release date: 2012-01-25 Last modified: 2017-08-23 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30. Cell Res., 22, 2012
4ERY	X-ray structure of WDR5-MLL3 Win motif peptide binary complex Descriptor: Histone-lysine N-methyltransferase MLL3, WD repeat-containing protein 5 Authors: Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. Deposit date: 2012-04-21 Release date: 2012-05-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
4ERQ	X-ray structure of WDR5-MLL2 Win motif peptide binary complex Descriptor: Histone-lysine N-methyltransferase MLL2, WD repeat-containing protein 5 Authors: Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. Deposit date: 2012-04-20 Release date: 2012-05-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.906 Å) Cite: Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
4ES0	X-ray structure of WDR5-SETd1b Win motif peptide binary complex Descriptor: Histone-lysine N-methyltransferase SETD1B, WD repeat-containing protein 5 Authors: Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. Deposit date: 2012-04-21 Release date: 2012-05-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.817 Å) Cite: Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
4ERZ	X-ray structure of WDR5-MLL4 Win motif peptide binary complex Descriptor: Histone-lysine N-methyltransferase MLL4, WD repeat-containing protein 5 Authors: Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. Deposit date: 2012-04-21 Release date: 2012-05-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
4EWR	X-ray structure of WDR5-SETd1a Win motif peptide binary complex Descriptor: Histone-lysine N-methyltransferase SETD1A, WD repeat-containing protein 5 Authors: Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. Deposit date: 2012-04-27 Release date: 2012-05-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.503 Å) Cite: Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
4ESG	X-ray structure of WDR5-MLL1 Win motif peptide binary complex Descriptor: Histone-lysine N-methyltransferase MLL, WD repeat-containing protein 5 Authors: Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. Deposit date: 2012-04-23 Release date: 2012-05-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012