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8DKB
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BU of 8dkb by Molmil
Crystal Structure of human YEATS4 in complex with Pfizer small molecule compound 3b
Descriptor: N-ethyl-1-{(3S,4S)-1-[(1-hydroxycyclohexyl)methyl]-3-methylpiperidin-4-yl}-2-methyl-1H-benzimidazole-5-carboxamide, YEATS domain-containing protein 4
Authors:Dias, J.M, Byrnes, L.J, Varghese, A.H.
Deposit date:2022-07-05
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.
J.Med.Chem., 66, 2023
5R68
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BU of 5r68 by Molmil
XChem group deposition -- Crystal Structure of human YEATS4 in complex with FM000199e
Descriptor: (1-methylbenzotriazol-5-yl)methanol, 1,2-ETHANEDIOL, YEATS domain-containing protein 4
Authors:Raux, B, Krojer, T, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Huber, K.V.M.
Deposit date:2020-02-29
Release date:2020-12-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:XChem group deposition
To Be Published
5R69
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BU of 5r69 by Molmil
XChem group deposition -- Crystal Structure of human YEATS4 in complex with XS038644e
Descriptor: 1,2-ETHANEDIOL, YEATS domain-containing protein 4, ~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide
Authors:Raux, B, Krojer, T, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Huber, K.V.M.
Deposit date:2020-02-29
Release date:2020-12-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:XChem group deposition
To Be Published
7JFY
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BU of 7jfy by Molmil
GAS41 YEATS domain in complex with 5
Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, N-(5-{3-[(2S)-1,3-thiazolidin-2-yl]azetidine-1-carbonyl}thiophen-2-yl)-L-prolinamide, ...
Authors:Linhares, B.M, Listunov, D, Winkler, A, Grembecka, J, Cierpicki, T.
Deposit date:2020-07-17
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.100557 Å)
Cite:GAS41 YEATS domain in complex with 5
To Be Published
7EIF
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BU of 7eif by Molmil
Crystal structure of GAS41 YEATS domain
Descriptor: GLYCEROL, YEATS domain-containing protein 4
Authors:Kikuchi, M, Umehara, T.
Deposit date:2021-03-30
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
5XTZ
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BU of 5xtz by Molmil
Crystal structure of GAS41 YEATS bound to H3K27ac peptide
Descriptor: ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4
Authors:Li, H.T, Zhao, D.
Deposit date:2017-06-21
Release date:2018-06-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.
Cell Discov, 4, 2018
5Y8V
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BU of 5y8v by Molmil
Crystal structure of GAS41
Descriptor: MAGNESIUM ION, YEATS domain-containing protein 4
Authors:Wang, Y, Hao, Q.
Deposit date:2017-08-21
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5VNA
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BU of 5vna by Molmil
Crystal structure of human YEATS domain
Descriptor: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SULFATE ION, ...
Authors:Cho, H.J, Cierpicki, T.
Deposit date:2017-04-29
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
5VNB
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BU of 5vnb by Molmil
YEATS in complex with histone H3
Descriptor: 1,2-ETHANEDIOL, H3K23acK27ac peptide, SULFATE ION, ...
Authors:Cho, H.J, Cierpicki, T.
Deposit date:2017-04-29
Release date:2018-09-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
8X15
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BU of 8x15 by Molmil
Structure of nucleosome-bound SRCAP-C in the apo state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
Deposit date:2023-11-06
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of nucleosome-bound SRCAP-C in the apo state
To Be Published
8X19
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BU of 8x19 by Molmil
Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
Deposit date:2023-11-06
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
To Be Published
8X1C
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BU of 8x1c by Molmil
Structure of nucleosome-bound SRCAP-C in the ADP-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
Deposit date:2023-11-06
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of nucleosome-bound SRCAP-C in the ADP-bound state
To Be Published
8I60
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BU of 8i60 by Molmil
Crystal structure of GAS41 YEATS domain in complex with histone H3K27cr
Descriptor: ALA-ARG-KCR-SER-ALA-PRO, GLYCEROL, SULFATE ION, ...
Authors:Konuma, T, Zhou, M.-M.
Deposit date:2023-01-26
Release date:2023-07-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Mol.Cell, 83, 2023
8IIZ
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BU of 8iiz by Molmil
Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K27ac peptide
Descriptor: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ...
Authors:Kikuchi, M, Umehara, T.
Deposit date:2023-02-24
Release date:2023-11-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8IIY
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BU of 8iiy by Molmil
Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K14ac peptide
Descriptor: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ...
Authors:Kikuchi, M, Umehara, T.
Deposit date:2023-02-24
Release date:2023-11-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
8IJ0
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BU of 8ij0 by Molmil
Crystal structure of GAS41 YEATS domain in complex with H3K9ac peptide
Descriptor: GLYCEROL, Histone H3.1, PENTAETHYLENE GLYCOL, ...
Authors:Kikuchi, M, Umehara, T.
Deposit date:2023-02-24
Release date:2023-11-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.
Proc.Natl.Acad.Sci.USA, 120, 2023

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