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6O5K
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BU of 6o5k by Molmil
Murine TRIM28 Bbox1 domain
Descriptor: Transcription intermediary factor 1-beta, ZINC ION
Authors:Sun, Y, Keown, J.R, Goldstone, D.C.
Deposit date:2019-03-03
Release date:2019-06-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family.
J.Mol.Biol., 431, 2019
6I9H
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BU of 6i9h by Molmil
Solution structure of TRIM28 RING domain
Descriptor: Transcription intermediary factor 1-beta, ZINC ION
Authors:Stevens, R.V, Esposito, D, Rittinger, K.
Deposit date:2018-11-23
Release date:2019-05-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity.
Life Sci Alliance, 2, 2019
6QAJ
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BU of 6qaj by Molmil
Structure of the tripartite motif of KAP1/TRIM28
Descriptor: Endolysin,Transcription intermediary factor 1-beta, ZINC ION
Authors:Stoll, G.A, Oda, S, Yu, M, Modis, Y.
Deposit date:2018-12-19
Release date:2019-07-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing.
Proc.Natl.Acad.Sci.USA, 116, 2019
7Z36
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BU of 7z36 by Molmil
Crystal structure of the KAP1 tripartite motif in complex with the ZNF93 KRAB domain
Descriptor: Endolysin,Transcription intermediary factor 1-beta,Isoform 2 of Transcription intermediary factor 1-beta, SMARCAD1 CUE1 domain, ZINC ION, ...
Authors:Stoll, G.A, Modis, Y.
Deposit date:2022-03-01
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and functional mapping of the KRAB-KAP1 repressor complex.
Embo J., 41, 2022
6QU1
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BU of 6qu1 by Molmil
Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain at 3.7 angstrom resolution.
Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta,Transcription intermediary factor 1-beta, ZINC ION
Authors:Newman, J.A, Aitkenhead, H, Gavard, A, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2019-02-26
Release date:2019-07-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.
Structure, 2019
6H3A
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BU of 6h3a by Molmil
Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain.
Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta, ZINC ION
Authors:Newman, J.A, Aitkenhead, H, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2018-07-17
Release date:2019-06-26
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (5.505 Å)
Cite:A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.
Structure, 27, 2019
2FMM
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BU of 2fmm by Molmil
Crystal Structure of EMSY-HP1 complex
Descriptor: Chromobox protein homolog 1, Protein EMSY, SULFATE ION
Authors:Huang, Y.
Deposit date:2006-01-09
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding.
Structure, 14, 2006
1DZ1
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BU of 1dz1 by Molmil
Mouse HP1 (M31) C terminal (shadow chromo) domain
Descriptor: MODIFIER 1 PROTEIN
Authors:Brasher, S.V, Smith, B.O, Fogh, R.H, Nietlispach, D, Thiru, A, Nielsen, P.R, Broadhurst, R.W, Ball, L.J, Murzina, N, Laue, E.D.
Deposit date:2000-02-11
Release date:2000-04-09
Last modified:2018-03-07
Method:SOLUTION NMR
Cite:The Structure of Mouse Hp1 Suggests a Unique Mode of Single Peptide Recognition by the Shadow Chromo Domain Dimer
Embo J., 19, 2000
5WY5
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BU of 5wy5 by Molmil
Crystal structure of MAGEG1 and NSE1 complex
Descriptor: MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ...
Authors:Yang, M, Gao, J.
Deposit date:2017-01-11
Release date:2017-05-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
3Q6S
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BU of 3q6s by Molmil
The crystal structure of the heterochromatin protein 1 beta chromoshadow domain complexed with a peptide from Shugoshin 1
Descriptor: Chromobox protein homolog 1, Shugoshin-like 1
Authors:Brautigam, C.A, Chaudhary, J, Yu, H.
Deposit date:2011-01-03
Release date:2011-12-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.
Mol Biol Cell, 22, 2011
1S4Z
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BU of 1s4z by Molmil
HP1 chromo shadow domain in complex with PXVXL motif of CAF-1
Descriptor: Chromatin assembly factor 1 subunit A, Chromobox protein homolog 1
Authors:Thiru, A, Nietlispach, D, Mott, H.R, Okuwaki, M, Lyon, D, Nielsen, P.R, Hirshberg, M, Verreault, A, Murzina, N.V, Laue, E.D.
Deposit date:2004-01-19
Release date:2004-03-23
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin.
Embo J., 23, 2004
2RO1
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BU of 2ro1 by Molmil
NMR Solution Structures of Human KAP1 PHD finger-bromodomain
Descriptor: Transcription intermediary factor 1-beta, ZINC ION
Authors:Zeng, L, Yap, K.L, Ivanov, A.V, Wang, X, Mujtaba, S, Plotnikova, O, Rauscher, F.J.
Deposit date:2008-03-04
Release date:2008-05-20
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing
Nat.Struct.Mol.Biol., 15, 2008
7ZDD
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BU of 7zdd by Molmil
Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K10ac histone peptide.
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase TRIM33, Histone H3.X, ...
Authors:Caria, S, Duclos, S, Crespillo, S, Errey, J, Barker, J.J.
Deposit date:2022-03-29
Release date:2022-06-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.625 Å)
Cite:Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33 alpha and TRIM33 beta Bromodomains.
Acs Chem.Biol., 17, 2022

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