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8ILY
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BU of 8ily by Molmil
Crystal structure of the RRM domain of human SETD1A
Descriptor: SET domain containing 1A, histone lysine methyltransferase
Authors:Bao, S, Xu, C.
Deposit date:2023-03-05
Release date:2023-04-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82.
Biochem.Biophys.Res.Commun., 658, 2023
3S8S
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BU of 3s8s by Molmil
Crystal structure of the RRM domain of human SETD1A
Descriptor: Histone-lysine N-methyltransferase SETD1A, UNKNOWN ATOM OR ION
Authors:Chao, X, Tempel, W, Bian, C, Cerovina, T, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-05-30
Release date:2011-06-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the RRM domain of human SETD1A
to be published
8ILZ
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BU of 8ilz by Molmil
Crystal structure of the RRM domain of human SETD1B
Descriptor: Histone-lysine N-methyltransferase SETD1B
Authors:Bao, S, Xu, C.
Deposit date:2023-03-05
Release date:2023-04-26
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82.
Biochem.Biophys.Res.Commun., 658, 2023
5SXM
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BU of 5sxm by Molmil
WDR5 in complex with MLL Win motif peptidomimetic
Descriptor: ACE-ALA-ARG-THR-GLU-VAL-TYR-NH2, WD repeat-containing protein 5
Authors:Alicea-Velazquez, N.L, Shinsky, S.A, Cosgrove, M.S.
Deposit date:2016-08-09
Release date:2016-09-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.
J.Biol.Chem., 291, 2016
4EWR
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BU of 4ewr by Molmil
X-ray structure of WDR5-SETd1a Win motif peptide binary complex
Descriptor: Histone-lysine N-methyltransferase SETD1A, WD repeat-containing protein 5
Authors:Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
Deposit date:2012-04-27
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
3UVN
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BU of 3uvn by Molmil
Crystal structure of WDR5 in complex with the WDR5-interacting motif of SET1A
Descriptor: Histone-lysine N-methyltransferase SETD1A, WD repeat-containing protein 5
Authors:Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F.
Deposit date:2011-11-30
Release date:2011-12-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Nucleic Acids Res., 40, 2012

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PDB entries from 2024-09-18

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