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2OOX
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2oox
CRYSTAL STRUCTURE OF THE ADENYLATE SENSOR FROM AMP-ACTIVATED PROTEIN KINASE COMPLEXED WITH AMP
Descriptor:SNF1-like protein kinase ssp2 (E.C.2.7.11.1), SPCC1919.03c protein, Hypothetical protein C1556.08c in chromosome I
Authors:Townley, R., Shapiro, L.
Deposit date:2007-01-26
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase.
Science, 315, 2007
2OOY
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2ooy
CRYSTAL STRUCTURE OF THE ADENYLATE SENSOR FROM AMP-ACTIVATED PROTEIN KINASE COMPLEXED WITH ATP
Descriptor:SNF1-like protein kinase ssp2 (E.C.2.7.11.1), SPCC1919.03c protein, Hypothetical protein C1556.08c in chromosome I
Authors:Townley, R., Shapiro, L.
Deposit date:2007-01-26
Release date:2007-02-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase.
Science, 315, 2007
2QLV
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2qlv
CRYSTAL STRUCTURE OF THE HETEROTRIMER CORE OF THE S. CEREVISIAE AMPK HOMOLOG SNF1
Descriptor:Carbon catabolite derepressing protein kinase (E.C.2.7.11.1), Protein SIP2, Nuclear protein SNF4
Authors:Amodeo, G.A., Rudolph, M.J., Tong, L.
Deposit date:2007-07-13
Release date:2007-09-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1.
Nature, 449, 2007
2QR1
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2qr1
CRYSTAL STRUCTURE OF THE ADENYLATE SENSOR FROM AMP-ACTIVATED PROTEIN KINASE IN COMPLEX WITH ADP
Descriptor:SNF1-like protein kinase ssp2 (E.C.2.7.11.1), SPCC1919.03c protein, AMP-activated protein kinase gamma subunit
Authors:Jin, X., Townley, R., Shapiro, L.
Deposit date:2007-07-27
Release date:2007-10-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Insight into AMPK Regulation: ADP Comes into Play.
Structure, 15, 2007
2QRC
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2qrc
CRYSTAL STRUCTURE OF THE ADENYLATE SENSOR FROM AMP-ACTIVATED PROTEIN KINASE IN COMPLEX WITH ADP AND AMP
Descriptor:SNF1-like protein kinase ssp2 (E.C.2.7.11.1), SPCC1919.03c protein, AMP-activated protein kinase gamma subunit
Authors:Jin, X., Townley, R., Shapiro, L.
Deposit date:2007-07-28
Release date:2007-10-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Insight into AMPK Regulation: ADP Comes into Play.
Structure, 15, 2007
2QRD
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2qrd
CRYSTAL STRUCTURE OF THE ADENYLATE SENSOR FROM AMP-ACTIVATED PROTEIN KINASE IN COMPLEX WITH ADP AND ATP
Descriptor:SNF1-like protein kinase ssp2 (E.C.2.7.11.1), SPCC1919.03c protein, AMP-activated protein kinase gamma subunit
Authors:Jin, X., Townley, R., Shapiro, L.
Deposit date:2007-07-28
Release date:2007-10-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural Insight into AMPK Regulation: ADP Comes into Play.
Structure, 15, 2007
2QRE
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2qre
CRYSTAL STRUCTURE OF THE ADENYLATE SENSOR FROM AMP-ACTIVATED PROTEIN KINASE IN COMPLEX WITH 5-AMINOIMIDAZOLE-4-CARBOXAMIDE 1-BETA-D-RIBOFURANOTIDE (ZMP)
Descriptor:SNF1-like protein kinase ssp2 (E.C.2.7.11.1), SPCC1919.03c protein, AMP-activated protein kinase gamma subunit
Authors:Jin, X., Townley, R., Shapiro, L.
Deposit date:2007-07-28
Release date:2007-10-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural Insight into AMPK Regulation: ADP Comes into Play.
Structure, 15, 2007
2V8Q
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2v8q
CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (E.C.2.7.11.1), 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-13
Release date:2007-09-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V92
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2v92
CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH ATP-AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (E.C.2.7.11.1), 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-20
Release date:2007-09-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V9J
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2v9j
CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH MG.ATP-AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (E.C.2.7.11.1), 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-23
Release date:2007-09-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2Y8L
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2y8l
STRUCTURE OF AN ACTIVE FORM OF MAMMALIAN AMPK IN COMPLEX WITH TWO ADP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (E.C.2.7.11.1), 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2011-02-07
Release date:2011-03-16
Modification date:2014-01-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2Y8Q
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2y8q
STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH ONE ADP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (E.C.2.7.11.1), 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2011-02-09
Release date:2011-03-16
Modification date:2012-11-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2YA3
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2ya3
STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH COUMARIN ADP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (E.C.2.7.11.1), 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2011-02-17
Release date:2011-03-16
Modification date:2011-04-20
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
3T4N
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3t4n
STRUCTURE OF THE REGULATORY FRAGMENT OF SACCHAROMYCES CEREVISIAE AMPK IN COMPLEX WITH ADP
Descriptor:Carbon catabolite-derepressing protein kinase (E.C.2.7.11.1), SNF1 protein kinase subunit beta-2, Nuclear protein SNF4
Authors:Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmdit, M.C., Gamblin, S.J., Carling, D.
Deposit date:2011-07-26
Release date:2011-11-09
Modification date:2011-11-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
3TDH
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3tdh
STRUCTURE OF THE REGULATORY FRAGMENT OF SCCHAROMYCES CEREVISIAE AMPK IN COMPLEX WITH AMP
Descriptor:Carbon catabolite-derepressing protein kinase (E.C.2.7.11.1), SNF1 protein kinase subunit beta-2, Nuclear protein SNF4
Authors:Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmidt, M.C., Gamblin, S.J., Carling, D.
Deposit date:2011-08-11
Release date:2011-11-09
Modification date:2011-11-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
3TE5
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3te5
STRUCTURE OF THE REGULATORY FRAGMENT OF SACCHROMYCES CEREVISIAE AMPK IN COMPLEX WITH NADH
Descriptor:Carbon catabolite-derepressing protein kinase (E.C.2.7.11.1), SNF1 protein kinase subunit beta-2, Nuclear protein SNF4
Authors:Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmidt, M.C., Gamblin, S.J., Carling, D.
Deposit date:2011-08-12
Release date:2011-11-09
Modification date:2011-11-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
4EAG
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4eag
CO-CRYSTAL STRUCTURE OF AN CHIMERIC AMPK CORE WITH ATP
Descriptor:EG:132E8.2 protein (E.C.2.7.11.-, 2.7.11.16), 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1
Authors:Chen, L., Wang, J., Zhang, Y.-Y., Yan, S.F., Neumann, D., Schlattner, U., Wang, Z.-X., Wu, J.-W.
Deposit date:2012-03-22
Release date:2012-06-06
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
4EAI
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4eai
CO-CRYSTAL STRUCTURE OF AN AMPK CORE WITH AMP
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, linker, 5'-AMP-activated protein kinase catalytic subunit alpha-1 (E.C.2.7.11.1, 2.7.11.26), 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1
Authors:Chen, L., Wang, J., Zhang, Y.-Y., Yan, S.F., Neumann, D., Schlattner, U., Wang, Z.-X., Wu, J.-W.
Deposit date:2012-03-22
Release date:2012-06-06
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.285 Å)
Cite:AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
4EAJ
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4eaj
CO-CRYSTAL OF AMPK CORE WITH AMP SOAKED WITH ATP
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, linker, 5'-AMP-activated protein kinase catalytic subunit alpha-1 (E.C.2.7.11.1, 2.7.11.26), 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1
Authors:Chen, L., Wang, J., Zhang, Y.-Y., Yan, S.F., Neumann, D., Schlattner, U., Wang, Z.-X., Wu, J.-W.
Deposit date:2012-03-22
Release date:2012-06-06
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.609 Å)
Cite:AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
4EAK
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4eak
CO-CRYSTAL STRUCTURE OF AN AMPK CORE WITH ATP
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, linker, 5'-AMP-activated protein kinase catalytic subunit alpha-1 (E.C.2.7.11.1, 2.7.11.26), 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1
Authors:Chen, L., Wang, J., Zhang, Y.-Y., Yan, S.F., Neumann, D., Schlattner, U., Wang, Z.-X., Wu, J.-W.
Deposit date:2012-03-22
Release date:2012-06-06
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
4EAL
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4eal
CO-CRYSTAL OF AMPK CORE WITH ATP SOAKED WITH AMP
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, linker, 5'-AMP-activated protein kinase catalytic subunit alpha-1 (E.C.2.7.11.1, 2.7.11.26), 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1
Authors:Chen, L., Wang, J., Zhang, Y.-Y., Yan, S.F., Neumann, D., Schlattner, U., Wang, Z.-X., Wu, J.-W.
Deposit date:2012-03-22
Release date:2012-06-06
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:AMP-activated protein kinase undergoes nucleotide-dependent conformational changes
Nat.Struct.Mol.Biol., 19, 2012
4CFE
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4cfe
STRUCTURE OF FULL LENGTH HUMAN AMPK IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991)
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 (E.C.2.7.11.1, 2.7.11.27, 2.7.11.31), 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
Authors:Xiao, B., Sanders, M.J., Carmena, D., Bright, N.J., Haire, L.F., Underwood, E., Patel, B.R., Heath, R.B., Walker, P.A., Hallen, S., Giordanetto, F., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2013-11-14
Release date:2013-12-25
Modification date:2014-02-12
Method:X-RAY DIFFRACTION (3.023 Å)
Cite:Structural Basis of Ampk Regulation by Small Molecule Activators.
Nat.Commun., 4, 2013
4CFF
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4cff
STRUCTURE OF FULL LENGTH HUMAN AMPK IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A THIENOPYRIDONE DERIVATIVE (A-769662)
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2 (E.C.2.7.11.1, 2.7.11.27, 2.7.11.31), 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
Authors:Xiao, B., Sanders, M.J., Carmena, D., Bright, N.J., Haire, L.F., Underwood, E., Patel, B.R., Heath, R.B., Walker, P.A., Hallen, S., Giordanetto, F., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2013-11-14
Release date:2013-12-25
Modification date:2014-02-12
Method:X-RAY DIFFRACTION (3.924 Å)
Cite:Structural Basis of Ampk Regulation by Small Molecule Activators.
Nat.Commun., 4, 2013
4CFH
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4cfh
STRUCTURE OF AN ACTIVE FORM OF MAMMALIAN AMPK
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1 (E.C.2.7.11.1), 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2013-11-18
Release date:2013-12-25
Modification date:2014-01-08
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
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entries available on 2014-11-19
00:00 UTC / 09:00 JST