1L9L
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GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES
Descriptor:GRANULYSIN
Authors:Anderson, D.H., Sawaya, M.R., Cascio, D., Ernst, W., Krensky, A., Modlin, R., Eisenberg, D.
Deposit date:2002-03-25
Release date:2002-11-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism
J.Mol.Biol., 325, 2002
2JS9
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STRUCTURE OF CAENOPORE-5 (81 PRO CIS CONFORMER)
Descriptor:Saposin-like protein family protein 5
Authors:Mysliwy, J., Grotzinger, J.
Deposit date:2007-07-02
Release date:2008-10-14
Modification date:2010-03-31
Method:SOLUTION NMR
Cite:Caenopore-5: the three-dimensional structure of an antimicrobial protein from Caenorhabditis elegans.
Dev.Comp.Immunol., 34, 2010
2JSA
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SOLUTION STRUCTURE OF CAENOPORE-5 (81 PRO TRANS CONFOMER)
Descriptor:Saposin-like protein family protein 5
Authors:Mysliwy, J., Grotzinger, J.
Deposit date:2007-07-02
Release date:2008-10-14
Modification date:2010-03-31
Method:SOLUTION NMR
Cite:Caenopore-5: the three-dimensional structure of an antimicrobial protein from Caenorhabditis elegans.
Dev.Comp.Immunol., 34, 2010
1M12
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NMR SOLUTION STRUCTURE OF HUMAN SAPOSIN C
Descriptor:SAPOSIN C
Authors:de Alba, E., Weiler, S., Tjandra, N.
Deposit date:2002-06-17
Release date:2003-07-29
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of human saposin C: pH-dependent interaction with phospholipid vesicles.
Biochemistry, 42, 2003
1N69
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CRYSTAL STRUCTURE OF HUMAN SAPOSIN B
Descriptor:Proactivator polypeptide, DI-STEAROYL-3-SN-PHOSPHATIDYLETHANOLAMINE
Authors:Ahn, V.E., Faull, K.F., Whitelegge, J.P., Fluharty, A.L., Prive, G.G.
Deposit date:2002-11-08
Release date:2003-01-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of saposin B reveals a dimeric shell for lipid binding
Proc.Natl.Acad.Sci.USA, 100, 2003
1SN6
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NMR SOLUTION STRUCTURE OF HUMAN SAPOSIN C IN SDS MICELLES
Descriptor:Proactivator polypeptide
Authors:Hawkins, C.A., de Alba, E., Tjandra, N.
Deposit date:2004-03-10
Release date:2005-03-01
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of human saposin C in a detergent environment.
J.Mol.Biol., 346, 2005
2DOB
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CRYSTAL STRUCTURE OF HUMAN SAPOSIN A
Descriptor:Proactivator polypeptide, Saposin A
Authors:Prive, G.G., Ahn, V.E.
Deposit date:2006-04-28
Release date:2006-07-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of saposins A and C.
Protein Sci., 15, 2006
2GTG
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CRYSTAL STRUCTURE OF HUMAN SAPOSIN C
Descriptor:Saposin C
Authors:Prive, G.G., Ahn, V.E.
Deposit date:2006-04-28
Release date:2006-07-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of saposins A and C.
Protein Sci., 15, 2006
2QYP
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ORTHORHOMBIC CRYSTAL STRUCTURE OF HUMAN SAPOSIN C DIMER IN OPEN CONFORMATION
Descriptor:Proactivator polypeptide
Authors:Rossmann, M., Saenger, W., Maier, T.
Deposit date:2007-08-15
Release date:2008-04-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2R0R
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CRYSTAL STRUCTURE OF HUMAN SAPOSIN D VARIANT SAPD K9E
Descriptor:Proactivator polypeptide
Authors:Rossmann, M., Saenger, W., Maier, T.
Deposit date:2007-08-21
Release date:2008-04-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2R1Q
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CRYSTAL STRUCTURE OF IODINATED HUMAN SAPOSIN D IN SPACE GROUP C2221
Descriptor:Proactivator polypeptide
Authors:Maier, T., Rossman, M., Saenger, W.
Deposit date:2007-08-23
Release date:2008-04-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2RB3
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CRYSTAL STRUCTURE OF HUMAN SAPOSIN D
Descriptor:Proactivator polypeptide
Authors:Maier, T., Rossman, M., Saenger, W.
Deposit date:2007-09-18
Release date:2008-04-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2Z9A
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CRYSTAL STRUCTURE OF HUMAN SAPOSIN C DIMER IN OPEN CONFORMATION
Descriptor:Proactivator polypeptide
Authors:Rossmann, M., Saenger, W., Maier, T.
Deposit date:2007-09-18
Release date:2008-04-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
3BQP
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CRYSTAL STRUCTURE OF HUMAN SAPOSIN D (ORTHORHOMBIC)
Descriptor:Proactivator polypeptide precursor [Contains: Saposin-A (Protein A); Saposin-B-Val; Saposin-B (Sphingolipid activator protein 1) (SAP-1) (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sulfatide/GM1 activator); Saposin-C (Co-beta-glucosidase) (A1 activator) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin-D (Protein C) (Component C)]
Authors:Prive, G.G., Popovic, K.
Deposit date:2007-12-20
Release date:2008-02-05
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
3BQQ
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CRYSTAL STRUCTURE OF HUMAN SAPOSIN D (TRICLINIC)
Descriptor:PROACTIVATOR POLYPEPTIDE
Authors:Prive, G.G., Popovic, K.
Deposit date:2007-12-20
Release date:2008-02-05
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the human ceramide activator protein saposin D.
Acta Crystallogr.,Sect.D, 64, 2008
4DDJ
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CRYSTAL STRUCTURE OF SAPOSIN A IN COMPLEX WITH LAURYLDIMETHYLAMINE-N-OXIDE (LDAO)
Descriptor:Saposin-A
Authors:Popovic, K., Prive, G.G.
Deposit date:2012-01-18
Release date:2012-02-15
Modification date:2012-03-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of saposin A lipoprotein discs.
Proc.Natl.Acad.Sci.USA, 109, 2012
4UEX
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STRUCTURE OF HUMAN SAPOSIN A AT LYSOSOMAL PH
Descriptor:PROSAPOSIN
Authors:Hill, C.H., Read, R.J., Deane, J.E.
Deposit date:2014-12-20
Release date:2015-07-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Human Saposin a at Lysosomal Ph.
Acta Crystallogr.,Sect.D, 71, 2015
4V2O
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STRUCTURE OF SAPOSIN B IN COMPLEX WITH CHLOROQUINE
Descriptor:SAPOSIN-B
Authors:Zubieta, C., Lai, X., Doyle, R.P.
Deposit date:2014-10-13
Release date:2015-12-09
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:The Lysosomal Protein Saposin B Binds Chloroquine.
Chemmedchem, 2015
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