2F01
| Epi-biotin complex with core streptavidin | Descriptor: | BIOTIN, EPI-BIOTIN, GLYCEROL, ... | Authors: | Le Trong, I, Aubert, D.G, Thomas, N.R, Stenkamp, R.E. | Deposit date: | 2005-11-10 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (0.85 Å) | Cite: | The high-resolution structure of (+)-epi-biotin bound to streptavidin. Acta Crystallogr.,Sect.D, 62, 2006
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3RY2
| Wild-type core streptavidin-biotin complex at atomic resolution | Descriptor: | BIOTIN, GLYCEROL, Streptavidin | Authors: | Stenkamp, R.E, Le Trong, I, Stayton, P.S, Lybrand, T.P. | Deposit date: | 2011-05-10 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Streptavidin and its biotin complex at atomic resolution. Acta Crystallogr.,Sect.D, 67, 2011
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1LUQ
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2GH7
| Epi-biotin complex with core streptavidin | Descriptor: | BIOTIN, EPI-BIOTIN, GLYCEROL, ... | Authors: | Le Trong, I, Aubert, D.G.L, Thomas, N.R, Stenkamp, R.E. | Deposit date: | 2006-03-26 | Release date: | 2006-04-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | The high-resolution structure of (+)-epi-biotin bound to streptavidin. Acta Crystallogr.,Sect.D, 62, 2006
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6T2L
| Streptavidin variants harbouring an artificial organocatalyst based cofactor | Descriptor: | 1,2-ETHANEDIOL, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide, GLYCEROL, ... | Authors: | Lechner, H, Hocker, B. | Deposit date: | 2019-10-09 | Release date: | 2020-10-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | An Artificial Cofactor Catalyzing the Baylis-Hillman Reaction with Designed Streptavidin as Protein Host*. Chembiochem, 22, 2021
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1Y55
| Crystal structure of the C122S mutant of E. Coli expressed avidin related protein 4 (AVR4)-biotin complex | Descriptor: | Avidin-related protein 4/5, BIOTIN, FORMIC ACID | Authors: | Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. | Deposit date: | 2004-12-02 | Release date: | 2005-05-24 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability. Acta Crystallogr.,Sect.D, 61, 2005
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3WYQ
| Crystal structure of the low-immunogenic core streptavidin mutant LISA-314 (Y22S/Y83S/R84K/E101D/R103K/E116N) at 1.0 A resolution | Descriptor: | BIOTIN, GLYCEROL, SULFATE ION, ... | Authors: | Kawato, T, Mizohata, E, Meshizuka, T, Doi, H, Kawamura, T, Matsumura, H, Yumura, K, Tsumoto, K, Kodama, T, Inoue, T, Sugiyama, A. | Deposit date: | 2014-09-05 | Release date: | 2014-12-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Crystal structure of streptavidin mutant with low immunogenicity. J.Biosci.Bioeng., 119, 2015
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3RY1
| Wild-type core streptavidin at atomic resolution | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Streptavidin | Authors: | Stenkamp, R.E, Wang, Z, Le Trong, I, Stayton, P.S, Lybrand, T.P. | Deposit date: | 2011-05-10 | Release date: | 2011-08-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Streptavidin and its biotin complex at atomic resolution. Acta Crystallogr.,Sect.D, 67, 2011
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5N8B
| CRYSTAL STRUCTURE OF STREPTAVIDIN WITH PEPTIDE AFPDYLAEYHGG | Descriptor: | ALA-PHE-PRO-ASP-TYR-LEU-ALA-GLU-TYR-HIS-GLY-GLY-NH2, Streptavidin | Authors: | Lyamichev, V, Goodrich, L, Sullivan, E, Bannen, R, Benz, J, Albert, T, Patel, J. | Deposit date: | 2017-02-23 | Release date: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target. Sci Rep, 7, 2017
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2FHL
| avidin related protein (AVR4)-BNA complex | Descriptor: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Avidin-related protein 4/5, FORMIC ACID | Authors: | Livnah, O, Prizant, M. | Deposit date: | 2005-12-26 | Release date: | 2006-03-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Factors dictating the pseudocatalytic efficiency of avidins J.Mol.Biol., 358, 2006
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5N8J
| CRYSTAL STRUCTURE OF STREPTAVIDIN WITH PEPTIDE D-amino acid containing peptide GyGlanvdessG | Descriptor: | GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY, ISOPROPYL ALCOHOL, Streptavidin | Authors: | Lyamichev, V, Goodrich, L, Sullivan, E, Bannen, R, Benz, J, Albert, T, Patel, J. | Deposit date: | 2017-02-23 | Release date: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target. Sci Rep, 7, 2017
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2OF8
| Crystal structure of AVR4 (D39A/C122S)-BNA complex | Descriptor: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Avidin-related protein 4/5, FORMIC ACID | Authors: | Livnah, O, Hayouka, R, Eisenberg-Domovich, Y. | Deposit date: | 2007-01-03 | Release date: | 2007-12-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester. Acta Crystallogr.,Sect.D, 64, 2008
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4CPE
| Wild-type streptavidin in complex with love-hate ligand 1 (LH1) | Descriptor: | (3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N-{2-[(2,6- diphenylphenyl)formamido]ethyl}pentanamide, STREPTAVIDIN | Authors: | Fairhead, M, Shen, D, Chan, L.K.M, Lowe, E.D, Donohoe, T.J, Howarth, M. | Deposit date: | 2014-02-06 | Release date: | 2014-08-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction. Bioorg.Med.Chem., 22, 2014
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3SZH
| Crystal structure of apo shwanavidin (P1 form) | Descriptor: | Avidin/streptavidin | Authors: | Livnah, O, Meir, A. | Deposit date: | 2011-07-19 | Release date: | 2012-04-11 | Last modified: | 2012-06-13 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Structural Adaptation of a Thermostable Biotin-binding Protein in a Psychrophilic Environment. J.Biol.Chem., 287, 2012
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6GH7
| WILDTYPE CORE-STREPTAVIDIN WITH a conjugated BIOTINYLATED PYRROLIDINE | Descriptor: | 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[(3~{R})-pyrrolidin-3-yl]pentanamide, Streptavidin | Authors: | Nodling, A.R, Tsai, Y.H, Luk, L.Y.P, Rizkallah, P, Jin, Y. | Deposit date: | 2018-05-04 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Reactivity and Selectivity of Iminium Organocatalysis Improved by a Protein Host. Angew.Chem.Int.Ed.Engl., 57, 2018
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5N8W
| CRYSTAL STRUCTURE OF STREPTAVIDIN with D-amino acid containing peptide GGwhdeatwkpG | Descriptor: | GLY-GLY-DTR-DHI-DAS-DGL-DAL-DTH-DTR-DLY, Streptavidin | Authors: | Lyamichev, V, Goodrich, L, Sullivan, E, Bannen, R, Benz, J, Albert, T, Patel, J. | Deposit date: | 2017-02-24 | Release date: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target. Sci Rep, 7, 2017
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5N8E
| CRYSTAL STRUCTURE OF STREPTAVIDIN WITH PEPTIDE RDPAPAWAHGGG | Descriptor: | ARG-ASP-PRO-ALA-PRO-ALA-TRP-ALA-HIS-GLY-GLY-GLY-NH2, SODIUM ION, Streptavidin | Authors: | Lyamichev, V, Goodrich, L, Sullivan, E, Bannen, R, Benz, J, Albert, T, Patel, J. | Deposit date: | 2017-02-23 | Release date: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target. Sci Rep, 7, 2017
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7EK9
| Crystal structure of apo streptavidin at cryogenic temperature | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Streptavidin | Authors: | DeMirci, H, Ayan, E, Destan, E, Ertem, F.B. | Deposit date: | 2021-04-04 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Crystal structure of apo streptavidin at cryogenic temperature To Be Published
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5N7X
| CRYSTAL STRUCTURE OF STREPTAVIDIN WITH PEPTIDE EWVHPQFEQKAK | Descriptor: | GLU-TRP-VAL-HIS-PRO-GLN-PHE-GLU-GLN-LYS-ALA-LYS Peptide, Streptavidin | Authors: | Lyamichev, V, Goodrich, L, Sullivan, E, Bannen, R, Benz, J, Albert, T, Patel, J. | Deposit date: | 2017-02-21 | Release date: | 2017-10-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target. Sci Rep, 7, 2017
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4CPF
| Wild-type streptavidin in complex with love-hate ligand 3 (LH3) | Descriptor: | STREPTAVIDIN, methyl 4-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H- thieno[3,4-d]imidazolidin-4-yl]pentanehydrazido}-3- [4-(methoxycarbonyl)phenyl]phenyl)benzoate | Authors: | Fairhead, M, Shen, D, Chan, L.K.M, Lowe, E.D, Donohoe, T.J, Howarth, M. | Deposit date: | 2014-02-06 | Release date: | 2014-08-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction. Bioorg.Med.Chem., 22, 2014
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1RXJ
| Crystal structure of streptavidin mutant (M2) where the L3,4 loop was replace by that of avidin | Descriptor: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Streptavidin | Authors: | Eisenberg-Domovich, Y, Pazy, Y, Nir, O, Raboy, B, Bayer, E.A, Wilchek, M, Livnah, O. | Deposit date: | 2003-12-18 | Release date: | 2004-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Structural elements responsible for conversion of streptavidin to a pseudoenzyme Proc.Natl.Acad.Sci.USA, 101, 2004
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1SWU
| STREPTAVIDIN MUTANT Y43F | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, STREPTAVIDIN | Authors: | Freitag, S, Le Trong, I, Klumb, L.A, Stayton, P.S, Stenkamp, R.E. | Deposit date: | 1998-10-12 | Release date: | 1999-11-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Atomic resolution structure of biotin-free Tyr43Phe streptavidin: what is in the binding site? Acta Crystallogr.,Sect.D, 55, 1999
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3T2X
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2G5L
| Streptavidin in complex with Nanotag | Descriptor: | (FME)(ASP)(VAL)(GLU)(ALA)(TRP)(LEU), GLYCEROL, SULFATE ION, ... | Authors: | Perbandt, M, Bruns, O, Vallazza, M, Lamla, T, Betzel, C, Erdmann, V.A. | Deposit date: | 2006-02-23 | Release date: | 2007-02-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | High resolution structure of Streptavidin in complex with a novel high affinity peptide tag mimicking the biotin binding motif To be Published
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2OFB
| Crystal structure of AVR4 (R112L/C122S)-BNA complex | Descriptor: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Avidin-related protein 4/5, FORMIC ACID | Authors: | Livnah, O, Hayouka, R, Eisenberg-Domovich, Y. | Deposit date: | 2007-01-03 | Release date: | 2007-12-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester. Acta Crystallogr.,Sect.D, 64, 2008
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