3J70
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MODEL OF GP120, INCLUDING VARIABLE REGIONS, IN COMPLEX WITH CD4 AND 17B
Descriptor:monoclonal antibody 17b light chain , monoclonal antibody 17b heavy chain, T-cell surface glycoprotein CD4, Envelope glycoprotein gp120, envelope glycoprotein gp41
Authors:Rasheed, M., Bettadapura, R., Bajaj, C.
Deposit date:2014-04-22
Release date:2015-08-26
Method:ELECTRON MICROSCOPY
Cite:Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State.
Structure, 23, 2015
4ZTO
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FAB/EPITOPE COMPLEX STRUCTURE OF RABBIT MONOCLONAL ANTIBODY R53 TARGETING AN EPITOPE IN HIV-1 GP120 C4 REGION
Descriptor:Light chain of Fab fragment of rabbit monoclonal antibody R53, Heavy chain of Fab fragment of rabbit monoclonal antibody R53, Epitope of rabbit monoclonal antibody R53
Authors:Pan, R., Kong, X.-P.
Deposit date:2015-05-14
Release date:2015-08-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of a novel rabbit monoclonal antibody R53 targeting an epitope in HIV-1 gp120 C4 region critical for receptor and co-receptor binding.
Emerg Microbes Infect, 4, 2015
4JPJ
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CRYSTAL STRUCTURE OF THE GERMLINE-TARGETING HIV-1 GP120 ENGINEERED OUTER DOMAIN, EOD-GT6
Descriptor:Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6
Authors:Julien, J.-P., Jardine, J., Schief, W.R., Wilson, I.A.
Deposit date:2013-03-19
Release date:2013-04-10
Modification date:2013-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rational HIV immunogen design to target specific germline B cell receptors.
Science, 340, 2013
4JPK
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CRYSTAL STRUCTURE OF THE GERMLINE-TARGETING HIV-1 GP120 ENGINEERED OUTER DOMAIN EOD-GT6 IN COMPLEX WITH A PUTATIVE VRC01 GERMLINE PRECURSOR FAB
Descriptor:Putative VRC01 germline precursor Fab heavy chain, Putative VRC01 germline precursor Fab light chain, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6
Authors:Julien, J.-P., Jardine, J., Schief, W.R., Wilson, I.A.
Deposit date:2013-03-19
Release date:2013-04-10
Modification date:2014-01-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rational HIV immunogen design to target specific germline B cell receptors.
Science, 340, 2013
3RJQ
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CRYSTAL STRUCTURE OF ANTI-HIV LLAMA VHH ANTIBODY A12 IN COMPLEX WITH C186 GP120
Descriptor:C186 gp120, Llama VHH A12
Authors:Chen, L., McLellan, J.S., Kwon, Y.D., Schmidt, S., Wu, X., Zhou, T., Yang, Y., Zhang, B., Forsman, A., Weiss, R.A., Verrips, T., Mascola, J., Kwong, P.D.
Deposit date:2011-04-15
Release date:2012-05-02
Modification date:2012-09-12
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120
To be Published
3TIH
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CRYSTAL STRUCTURE OF UNLIGANDED HIV-1 CLADE C STRAIN ZM109F.PB4 GP120 CORE
Descriptor:HIV-1 clade C ZM109F.PB4 gp120
Authors:Kwon, Y.D., Kwong, P.D.
Deposit date:2011-08-20
Release date:2012-04-04
Modification date:2014-11-12
Method:X-RAY DIFFRACTION (4 Å)
Cite:Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.
Proc.Natl.Acad.Sci.USA, 109, 2012
3TYG
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CRYSTAL STRUCTURE OF BROAD AND POTENT HIV-1 NEUTRALIZING ANTIBODY PGT128 IN COMPLEX WITH A GLYCOSYLATED ENGINEERED GP120 OUTER DOMAIN WITH MINIV3 (EODMV3)
Descriptor:Envelope glycoprotein gp160, PGT128 light chain, Ig lambda-2 chain C regions, PGT128 heavy chain, Ig gamma-1 chain C region
Authors:Pejchal, R., Huang, P.S., Schief, W.R., Stanfield, R.L., Wilson, I.A.
Deposit date:2011-09-25
Release date:2011-10-19
Modification date:2011-12-07
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.
Science, 334, 2011
3IDX
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CRYSTAL STRUCTURE OF HIV-GP120 CORE IN COMPLEX WITH CD4-BINDING SITE ANTIBODY B13, SPACE GROUP C222
Descriptor:HIV-1 HxBc2 gp120 core, Fab b13 heavy chain, Fab b13 light chain
Authors:Chen, L., Kwon, Y.D., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z.Y., Zhang, M.Y., Arthos, J., Burton, D.R., Dimitrov, D.S., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D.
Deposit date:2009-07-22
Release date:2009-11-17
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
3IDY
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CRYSTAL STRUCTURE OF HIV-GP120 CORE IN COMPLEX WITH CD4-BINDING SITE ANTIBODY B13, SPACE GROUP C2221
Descriptor:HIV-1 HxBc2 gp120 core, Fab b13 heavy chain, Fab b13 light chain
Authors:Chen, L., Kwon, Y.D., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z.Y., Zhang, M.Y., Arthos, J., Burton, D.R., Dimitrov, D.S., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D.
Deposit date:2009-07-22
Release date:2009-11-17
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
3DNL
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MOLECULAR STRUCTURE FOR THE HIV-1 GP120 TRIMER IN THE B12-BOUND STATE
Descriptor:HIV-1 envelope glycoprotein gp120
Authors:Borgnia, M.J., Liu, J., Bartesaghi, A., Sapiro, G., Subramaniam, S.
Deposit date:2008-07-02
Release date:2008-08-19
Modification date:2009-02-24
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
3DNN
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MOLECULAR STRUCTURE FOR THE HIV-1 GP120 TRIMER IN THE UNLIGANDED STATE
Descriptor:HIV-1 envelope glycoprotein gp120
Authors:Borgnia, M.J., Liu, J., Bartesaghi, A., Sapiro, G., Subramaniam, S.
Deposit date:2008-07-02
Release date:2008-08-19
Modification date:2009-02-24
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
3DNO
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MOLECULAR STRUCTURE FOR THE HIV-1 GP120 TRIMER IN THE CD4-BOUND STATE
Descriptor:HIV-1 envelope glycoprotein gp120
Authors:Borgnia, M.J., Liu, J., Bartesaghi, A., Sapiro, G., Subramaniam, S.
Deposit date:2008-07-02
Release date:2008-08-19
Modification date:2012-09-05
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
2NY7
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HIV-1 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH THE BROADLY NEUTRALIZING CD4-BINDING-SITE ANTIBODY B12
Descriptor:ENVELOPE GLYCOPROTEIN GP120, ANTIBODY b12, HEAVY CHAIN, ANTIBODY b12, LIGHT CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
1RZJ
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HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEINS GP120 AND CD4/ANTIBODY 17B-LIGHT AND HEAVY CHAINS COMPLEX
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1G9M
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HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, CD4, ANTIBODY 17B-LIGHT AND HEAVY CHAIN COMPLEX
Authors:Kwong, P.D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:2000-11-24
Release date:2000-12-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1GC1
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HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY
Descriptor:ENVELOPE PROTEIN GP120, CD4, ANTIBODY 17B
Authors:Kwong, P.D., Wyatt, R., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:1998-06-15
Release date:1998-07-08
Modification date:2013-09-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
Nature, 393, 1998
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