5A31
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STRUCTURE OF THE HUMAN APC-CDH1-HSL1-UBCH10 COMPLEX.
Descriptor:ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, CELL DIVISION CYCLE PROTEIN 23 HOMOLOG, ANAPHASE-PROMOTING COMPLEX SUBUNIT 15, ANAPHASE-PROMOTING COMPLEX SUBUNIT 16, ANAPHASE-PROMOTING COMPLEX SUBUNIT 3, ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26, ANAPHASE-PROMOTING COMPLEX SUBUNIT 4, ANAPHASE-PROMOTING COMPLEX SUBUNIT 6, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 13, ANAPHASE-PROMOTING COMPLEX SUBUNIT 2, ANAPHASE-PROMOTING COMPLEX SUBUNIT 5, FUSION PROTEIN - UBIQUITIN-CONJUGATING ENZYME E2 C, UBIQUITIN-CONJUGATING ENZYME E2 S (E.C.2.3.2.23, 2.3.2.24, 2.3.2.23), THE ANAPHASE-PROMOTING COMPLEX CHAIN R, THE ANAPHASE-PROMOTING COMPLEX CHAIN T, THE ANAPHASE-PROMOTING COMPLEX CHAIN U, THE ANAPHASE-PROMOTING COMPLEX CHAIN V, ANAPHASE-PROMOTING COMPLEX SUBUNIT 7
Authors:Chang, L., Zhang, Z., Yang, J., Mclaughlin, S.H., Barford, D.
Deposit date:2015-05-26
Release date:2015-11-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Atomic Structure of the Apc/C and its Mechanism of Protein Ubiquitination.
Nature, 522, 2015
4UI9
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ATOMIC STRUCTURE OF THE HUMAN ANAPHASE-PROMOTING COMPLEX
Descriptor:ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, CELL DIVISION CYCLE PROTEIN 23 HOMOLOG, ANAPHASE-PROMOTING COMPLEX SUBUNIT 15, ANAPHASE-PROMOTING COMPLEX SUBUNIT 16, CELL DIVISION CYCLE PROTEIN 27 HOMOLOG, ANAPHASE-PROMOTING COMPLEX SUBUNIT CDC26, ANAPHASE-PROMOTING COMPLEX SUBUNIT 4, CELL DIVISION CYCLE PROTEIN 16 HOMOLOG, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 13, ANAPHASE-PROMOTING COMPLEX SUBUNIT 2, ANAPHASE-PROMOTING COMPLEX SUBUNIT 5, FIZZY-RELATED PROTEIN HOMOLOG, F-BOX ONLY PROTEIN 5, PEPTIDE, ANAPHASE-PROMOTING COMPLEX SUBUNIT 7
Authors:Chang, L., Zhang, Z., Yang, J., McLaughlin, S.H., Barford, D.
Deposit date:2015-03-27
Release date:2015-06-17
Modification date:2015-07-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
4RG6
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CRYSTAL STRUCTURE OF APC3-APC16 COMPLEX
Descriptor:Cell division cycle protein 27 homolog, Anaphase-promoting complex subunit 16
Authors:Yamaguchi, M., Yu, S., Miller, D.J., Schulman, B.A.
Deposit date:2014-09-29
Release date:2014-12-24
Modification date:2015-04-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
4RG7
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CRYSTAL STRUCTURE OF APC3
Descriptor:Cell division cycle protein 27 homolog
Authors:Yamaguchi, M., Yu, S., Miller, D.J., Schulman, B.A.
Deposit date:2014-09-29
Release date:2014-12-24
Modification date:2015-04-15
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
4RG9
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CRYSTAL STRUCTURE OF APC3-APC16 COMPLEX (SELENOMETHIONINE DERIVATIVE)
Descriptor:Cell division cycle protein 27 homolog, Anaphase-promoting complex subunit 16
Authors:Yamaguchi, M., Yu, S., Miller, D.J., Schulman, B.A.
Deposit date:2014-09-29
Release date:2014-12-24
Modification date:2015-04-15
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
4CGV
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FIRST TPR OF SPAGHETTI (RPAP3) BOUND TO HSP90 PEPTIDE SRMEEVD
Descriptor:RNA POLYMERASE II-ASSOCIATED PROTEIN 3, HEAT SHOCK PROTEIN HSP 90-ALPHA
Authors:Roe, S.M., Pal, M.
Deposit date:2013-11-26
Release date:2014-05-14
Modification date:2014-06-25
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1.
Structure, 22, 2014
4KBQ
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STRUCTURE OF THE CHIP-TPR DOMAIN IN COMPLEX WITH THE HSC70 LID-TAIL DOMAINS
Descriptor:E3 ubiquitin-protein ligase CHIP (E.C.6.3.2.-), Heat shock cognate 71 kDa protein
Authors:Page, R.C., Amick, J., Nix, J.C., Misra, S.
Deposit date:2013-04-23
Release date:2015-01-14
Modification date:2015-03-18
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:A Bipartite Interaction between Hsp70 and CHIP Regulates Ubiquitination of Chaperoned Client Proteins.
Structure, 23, 2015
4JA7
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RAT PP5 CO-CRYSTALLIZED WITH P5SA-2
Descriptor:Serine/threonine-protein phosphatase 5 (E.C.3.1.3.16)
Authors:Haslbeck, V., Helmuth, M., Alte, F., Popowicz, G., Schmidt, W., Weiwad, M., Fischer, G., Gemmecker, G., Sattler, M., Striggow, F., Groll, M., Richter, K.
Deposit date:2013-02-18
Release date:2014-02-19
Modification date:2016-02-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selective activators of protein phosphatase 5 target the autoinhibitory mechanism.
Biosci.Rep., 35, 2015
4JA9
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RAT PP5 APO
Descriptor:Serine/threonine-protein phosphatase 5 (E.C.3.1.3.16)
Authors:Haslbeck, V., Helmuth, M., Alte, F., Popowicz, G., Schmidt, W., Weiwad, M., Fischer, G., Gemmecker, G., Sattler, M., Striggow, F., Groll, M., Richter, K.
Deposit date:2013-02-18
Release date:2014-02-19
Modification date:2016-02-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Selective activators of protein phosphatase 5 target the autoinhibitory mechanism.
Biosci.Rep., 35, 2015
4GCN
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N-TERMINAL DOMAIN OF STRESS-INDUCED PROTEIN-1 (STI-1) FROM C.ELEGANS
Descriptor:Protein STI-1
Authors:Osipiuk, J., Bigelow, L., Gu, M., Van Oosten-Hawle, P., Morimoto, R.I., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2012-07-30
Release date:2012-08-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
4GCO
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CENTRAL DOMAIN OF STRESS-INDUCED PROTEIN-1 (STI-1) FROM C.ELEGANS
Descriptor:Protein STI-1
Authors:Osipiuk, J., Bigelow, L., Gu, M., Van Oosten-Hawle, P., Morimoto, R.I., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2012-07-30
Release date:2012-08-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Central domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
2LNI
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SOLUTION NMR STRUCTURE OF STRESS-INDUCED-PHOSPHOPROTEIN 1 STI1 FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4403E
Descriptor:Stress-induced-phosphoprotein 1
Authors:Tang, Y., Liu, G., Hamilton, K., Ciccosanti, C., Shastry, R., Rost, B., Acton, T.B., Xiao, R., Everett, J.K., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-12-28
Release date:2012-03-14
Method:SOLUTION NMR
Cite:Northeast Structural Genomics Consortium Target HR4403E
To be Published
3UQ3
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TPR2AB-DOMAIN:PHSP90-COMPLEX OF YEAST STI1
Descriptor:Heat shock protein STI1, pHSP90-C-terminus from yeast
Authors:Schmid, A.B., Lagleder, S., Graewert, M.A., Roehl, A., Hagn, F., Wandinger, S.K., Cox, M.B., Demmer, O., Richter, K., Groll, M., Kessler, H., Buchner, J.
Deposit date:2011-11-19
Release date:2012-01-18
Modification date:2012-04-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
3UPV
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TPR2B-DOMAIN:PHSP70-COMPLEX OF YEAST STI1
Descriptor:Heat shock protein STI1, Heat shock protein SSA4
Authors:Schmid, A.B., Lagleder, S., Graewert, M.A., Roehl, A., Hagn, F., Wandinger, S.K., Cox, M.B., Demmer, O., Richter, K., Groll, M., Kessler, H.
Deposit date:2011-11-18
Release date:2012-01-25
Modification date:2012-04-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Embo J., 31, 2012
2Y4T
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CRYSTAL STRUCTURE OF THE HUMAN CO-CHAPERONE P58(IPK)
Descriptor:DNAJ HOMOLOG SUBFAMILY C MEMBER 3
Authors:Svard, M., Biterova, E.I., Bourhis, J.-M., Guy, J.E.
Deposit date:2011-01-10
Release date:2011-08-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Crystal Structure of the Human Co-Chaperone P58Ipk
Plos One, 6, 2011
2Y4U
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CRYSTAL STRUCTURE OF HUMAN P58(IPK) IN SPACE GROUP P312
Descriptor:DNAJ HOMOLOG SUBFAMILY C MEMBER 3
Authors:Svard, M., Biterova, E.I., Bourhis, J.-M., Guy, J.E.
Deposit date:2011-01-10
Release date:2011-08-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Crystal Structure of the Human Co-Chaperone P58Ipk
Plos One, 6, 2011
3NF1
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CRYSTAL STRUCTURE OF THE TPR DOMAIN OF KINESIN LIGHT CHAIN 1
Descriptor:Kinesin light chain 1
Authors:Tong, Y., Tempel, W., Shen, L., Shen, Y., Nedyalkova, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2010-06-09
Release date:2011-05-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the TPR domain of kinesin light chain 1
to be published
3LCA
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STRUCTURE OF TOM71 COMPLEXED WITH HSP70 SSA1 C TERMINAL TAIL INDICATING CONFORMATIONAL PLASTICITY
Descriptor:Protein TOM71, Heat shock protein SSA1
Authors:Li, J.Z., Sha, B.D
Deposit date:2010-01-10
Release date:2010-12-22
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The structural plasticity of Tom71 for mitochondrial precursor translocations.
Acta Crystallogr.,Sect.F, 66, 2010
2WQH
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CRYSTAL STRUCTURE OF CTPR3Y3
Descriptor:CTPR3Y3
Authors:Krachler, A.M., Sharma, A., Kleanthous, C.
Deposit date:2009-08-21
Release date:2010-04-07
Modification date:2010-05-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Self-Association of Tpr Domains: Lessons Learned from a Designed, Consensus-Based Tpr Oligomer.
Proteins, 78, 2010
3IEG
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CRYSTAL STRUCTURE OF P58(IPK) TPR DOMAIN AT 2.5 A
Descriptor:DnaJ homolog subfamily C member 3
Authors:Tao, J., Sha, B.
Deposit date:2009-07-22
Release date:2010-03-31
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal Structure of P58(IPK) TPR Fragment Reveals the Mechanism for its Molecular Chaperone Activity in UPR.
J.Mol.Biol., 64, 2010
3FWV
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CRYSTAL STRUCTURE OF A REDESIGNED TPR PROTEIN, T-MOD(VMY), IN COMPLEX WITH MEEVF PEPTIDE
Descriptor:Crystal Structure of a Redesigned TPR Protein, T-MOD(VMY), in Complex with Peptide
Authors:Jackrel, M.E., Valverde, R., Regan, L.
Deposit date:2009-01-19
Release date:2009-04-21
Modification date:2011-08-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redesign of a protein-peptide interaction: characterization and applications
Protein Sci., 18, 2009
3FP2
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CRYSTAL STRUCTURE OF TOM71 COMPLEXED WITH HSP82 C-TERMINAL FRAGMENT
Descriptor:---
Authors:Li, J., Qian, X., Hu, J., Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3FP3
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CRYSTAL STRUCTURE OF TOM71
Descriptor:TPR repeat-containing protein YHR117W
Authors:Li, J., Qian, X., Hu, J., Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Modification date:2009-11-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3FP4
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CRYSTAL STRUCTURE OF TOM71 COMPLEXED WITH SSA1 C-TERMINAL FRAGMENT
Descriptor:TPR repeat-containing protein YHR117W, Ssa1
Authors:Li, J., Qian, X., Hu, J., Sha, B.
Deposit date:2009-01-03
Release date:2009-07-28
Modification date:2009-11-10
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
3ESK
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STRUCTURE OF HOP TPR2A DOMAIN IN COMPLEX WITH THE NON-COGNATE HSC70 PEPTIDE LIGAND
Descriptor:Stress-induced-phosphoprotein 1, Heat shock cognate 71 kDa protein
Authors:Kajander, T., Regan, L.
Deposit date:2008-10-06
Release date:2009-07-07
Modification date:2014-04-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering.
J.Biol.Chem., 284, 2009
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