2NC9

Apo solution structure of Hop TPR2A

Summary for 2NC9

• Entry DOI: 10.2210/pdb2nc9/pdb
• NMR Information: BMRB: 26011
• Descriptor: Stress-induced-phosphoprotein 1 (1 entity in total)
• Functional Keywords: chaperone, heat-shock, hsp90, tpr
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 15569.57

Authors

Darby, J.F.,Vidler, L.R.,Simpson, P.J.,Matthews, S.J.,Sharp, S.Y.,Pearl, L.H.,Hoelder, S.,Workman, P. (deposition date: 2016-03-23, release date: 2017-03-29, Last modification date: 2020-10-28)

• Primary citation: Darby, J.F.,Vidler, L.R.,Simpson, P.J.,Al-Lazikani, B.,Matthews, S.J.,Sharp, S.Y.,Pearl, L.H.,Hoelder, S.,Workman, P.; Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.; Sci Rep, 10:16000-16000, 2020; PubMed: 32994435; DOI: 10.1038/s41598-020-71969-w

Experimental method

SOLUTION NMR