1AW5
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1B4E
| X-ray structure of 5-aminolevulinic acid dehydratase complexed with the inhibitor levulinic acid | Descriptor: | GLYCEROL, LAEVULINIC ACID, PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE), ... | Authors: | Erskine, P.T, Cooper, J.B, Lewis, G, Spencer, P, Wood, S.P, Shoolingin-Jordan, P.M. | Deposit date: | 1998-12-19 | Release date: | 1999-12-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution. Biochemistry, 38, 1999
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1B4K
| High resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydratase | Descriptor: | LAEVULINIC ACID, MAGNESIUM ION, PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE), ... | Authors: | Frankenberg, N, Jahn, D, Heinz, D.W. | Deposit date: | 1998-12-22 | Release date: | 1999-07-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase. J.Mol.Biol., 289, 1999
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1YLV
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID | Descriptor: | LAEVULINIC ACID, PROTEIN (5-AMINOLAEVULINIC ACID DEHYDRATASE), ZINC ION | Authors: | Erskine, P.T, Newbold, R, Roper, J, Coker, A, Warren, M.J, Shoolingin-Jordan, P.M, Wood, S.P, Cooper, J.B. | Deposit date: | 1999-02-22 | Release date: | 2000-02-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The Schiff base complex of yeast 5-aminolaevulinic acid dehydratase with laevulinic acid. Protein Sci., 8, 1999
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1QML
| Hg complex of yeast 5-aminolaevulinic acid dehydratase | Descriptor: | 5-AMINOLAEVULINIC ACID DEHYDRATASE, MERCURY (II) ION | Authors: | Erskine, P.T, Senior, N, Warren, M.J, Wood, S.P, Cooper, J.B. | Deposit date: | 1999-10-02 | Release date: | 2000-10-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites Acta Crystallogr.,Sect.D, 56, 2000
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1QNV
| yeast 5-aminolaevulinic acid dehydratase Lead (Pb) complex | Descriptor: | 5-AMINOLAEVULINIC ACID DEHYDRATASE, LEAD (II) ION | Authors: | Erskine, P.T, Senior, N.M, Warren, M.J, Wood, S.P, Cooper, J.B. | Deposit date: | 1999-10-21 | Release date: | 2000-10-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites Acta Crystallogr.,Sect.D, 56, 2000
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1E51
| Crystal structure of native human erythrocyte 5-aminolaevulinic acid dehydratase | Descriptor: | 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, SULFATE ION, ... | Authors: | Mills-Davies, N.L, Thompson, D, Cooper, J.B, Shoolingin-Jordan, P.M. | Deposit date: | 2000-07-13 | Release date: | 2001-07-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | The Crystal Structure of Human Ala-Dehydratase To be Published
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1I8J
| CRYSTAL STRUCTURE OF PORPHOBILINOGEN SYNTHASE COMPLEXED WITH THE INHIBITOR 4,7-DIOXOSEBACIC ACID | Descriptor: | 4,7-DIOXOSEBACIC ACID, MAGNESIUM ION, PORPHOBILINOGEN SYNTHASE, ... | Authors: | Kervinen, J, Jaffe, E.K, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A. | Deposit date: | 2001-03-14 | Release date: | 2001-06-20 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic basis for suicide inactivation of porphobilinogen synthase by 4,7-dioxosebacic acid, an inhibitor that shows dramatic species selectivity. Biochemistry, 40, 2001
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1H7P
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-KETO-5-AMINO-HEXANOIC (KAH) AT 1.64 A RESOLUTION | Descriptor: | 5-AMINO-4-HYDROXYHEXANOIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Newbold, R, Brindley, A.A, Wood, S.P, Shoolingin-Jordan, P.M, Warren, M.J, Cooper, J.B. | Deposit date: | 2001-07-09 | Release date: | 2001-07-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors J.Mol.Biol., 312, 2001
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1H7O
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 5-AMINOLAEVULINIC ACID AT 1.7 A RESOLUTION | Descriptor: | 5-AMINOLAEVULINIC ACID DEHYDRATASE, DELTA-AMINO VALERIC ACID, ZINC ION | Authors: | Erskine, P.T, Newbold, R, Brindley, A.A, Wood, S.P, Shoolingin-Jordan, P.M, Warren, M.J, Cooper, J.B. | Deposit date: | 2001-07-09 | Release date: | 2001-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors J.Mol.Biol., 312, 2001
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1H7R
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH SUCCINYLACETONE AT 2.0 A RESOLUTION. | Descriptor: | 4,6-DIOXOHEPTANOIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Newbold, R, Brindley, A.A, Wood, S.P, Shoolingin-Jordan, P.M, Warren, M.J, Cooper, J.B. | Deposit date: | 2001-07-09 | Release date: | 2001-07-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors J.Mol.Biol., 312, 2001
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1H7N
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID AT 1.6 A RESOLUTION | Descriptor: | 5-AMINOLAEVULINIC ACID DEHYDRATASE, LAEVULINIC ACID, ZINC ION | Authors: | Erskine, P.T, Newbold, R, Brindley, A.A, Wood, S.P, Shoolingin-Jordan, P.M, Warren, M.J, Cooper, J.B. | Deposit date: | 2001-07-09 | Release date: | 2001-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors J.Mol.Biol., 312, 2001
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1EB3
| YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 4,7-DIOXOSEBACIC ACID COMPLEX | Descriptor: | 4,7-DIOXOSEBACIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Coates, L, Newbold, R, Brindley, A.A, Stauffer, F, Wood, S.P, Warren, M.J, Cooper, J.B, Shoolingin-Jordan, P.M, Neier, R. | Deposit date: | 2001-07-18 | Release date: | 2001-08-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors FEBS Lett., 503, 2001
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1GJP
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-OXOSEBACIC ACID | Descriptor: | 4-OXODECANEDIOIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Coates, L, Newbold, R, Brindley, A.A, Wood, S.P, Warren, M.J, Cooper, J.B, Shoolingin-Jordan, P.M, Neier, R. | Deposit date: | 2001-08-01 | Release date: | 2001-08-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors FEBS Lett., 503, 2001
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1L6S
| Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4,7-Dioxosebacic Acid | Descriptor: | 4,7-DIOXOSEBACIC ACID, MAGNESIUM ION, PORPHOBILINOGEN SYNTHASE, ... | Authors: | Jaffe, E.K, Kervinen, J, Martins, J, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A. | Deposit date: | 2002-03-13 | Release date: | 2002-04-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid J.Biol.Chem., 277, 2002
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1L6Y
| Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4-Oxosebacic Acid | Descriptor: | 4-OXODECANEDIOIC ACID, GLYCEROL, MAGNESIUM ION, ... | Authors: | Jaffe, E.K, Kervinen, J, Martins, J, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A. | Deposit date: | 2002-03-14 | Release date: | 2002-04-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid J.Biol.Chem., 277, 2002
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1GZG
| Complex of a Mg2-dependent porphobilinogen synthase from Pseudomonas aeruginosa (mutant D139N) with 5-fluorolevulinic acid | Descriptor: | 5-FLUOROLEVULINIC ACID, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, ... | Authors: | Frere, F, Schubert, W.-D, Stauffer, F, Frankenberg, N, Neier, R, Jahn, D, Heinz, D.W. | Deposit date: | 2002-05-21 | Release date: | 2002-06-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structure of porphobilinogen synthase from Pseudomonas aeruginosa in complex with 5-fluorolevulinic acid suggests a double Schiff base mechanism. J. Mol. Biol., 320, 2002
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1OHL
| YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE PUTATIVE CYCLIC REACTION INTERMEDIATE COMPLEX | Descriptor: | 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, BETA-MERCAPTOETHANOL, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ... | Authors: | Erskine, P.T, Coates, L, Butler, D, Youell, J.H, Brindley, A.A, Wood, S.P, Warren, M.J, Shoolingin-Jordan, P.M, Cooper, J.B. | Deposit date: | 2003-05-27 | Release date: | 2003-06-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-Ray Structure of a Putative Reaction Intermediateof 5-Aminolaevulinic Acid Dehydratase Biochem.J., 373, 2003
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1PV8
| Crystal structure of a low activity F12L mutant of human porphobilinogen synthase | Descriptor: | 3-(2-AMINOETHYL)-4-(AMINOMETHYL)HEPTANEDIOIC ACID, Delta-aminolevulinic acid dehydratase, ZINC ION | Authors: | Breinig, S, Kervinen, J, Stith, L, Wasson, A.S, Fairman, R, Wlodawer, A, Zdanov, A, Jaffe, E.K. | Deposit date: | 2003-06-26 | Release date: | 2003-09-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase. Nat.Struct.Biol., 10, 2003
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1W1Z
| Structure of the plant like 5-Aminolaevulinic Acid Dehydratase from Chlorobium vibrioforme | Descriptor: | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, LAEVULINIC ACID, MAGNESIUM ION | Authors: | Coates, L, Beaven, G, Erskine, P.T, Beale, S.I, Avissar, Y.J, Gill, R, Mohammed, F, Wood, S.P, Shoolingin-Jordan, P, Cooper, J.B. | Deposit date: | 2004-06-24 | Release date: | 2004-09-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The X-ray structure of the plant like 5-aminolaevulinic acid dehydratase from Chlorobium vibrioforme complexed with the inhibitor laevulinic acid at 2.6 A resolution. J. Mol. Biol., 342, 2004
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1W31
| YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 5-HYDROXYLAEVULINIC ACID COMPLEX | Descriptor: | 5-HYDROXYLAEVULINIC ACID, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Coates, L, Newbold, R, Brindley, A.A, Stauffer, F, Beaven, G.D.E, Gill, R, Wood, S.P, Warren, M.J, Cooper, J.B, Shoolingin-Jordan, P.M, Neier, R. | Deposit date: | 2004-07-11 | Release date: | 2005-08-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with the Inhibitor 5-Hydroxylaevulinic Acid Acta Crystallogr.,Sect.D, 61, 2005
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1W56
| Stepwise introduction of zinc binding site into porphobilinogen synthase of Pseudomonas aeruginosa (mutations A129C and D131C) | Descriptor: | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, MAGNESIUM ION, ... | Authors: | Frere, F, Reents, H, Schubert, W.-D, Heinz, D.W, Jahn, D. | Deposit date: | 2004-08-05 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro J.Mol.Biol., 345, 2005
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1W54
| Stepwise introduction of a zinc binding site into Porphobilinogen synthase from Pseudomonas aeruginosa (mutation D139C) | Descriptor: | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, MAGNESIUM ION, ... | Authors: | Frere, F, Reents, H, Schubert, W.-D, Heinz, D.W, Jahn, D. | Deposit date: | 2004-08-05 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro J.Mol.Biol., 345, 2005
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1W5M
| Stepwise introduction of zinc binding site into porphobilinogen synthase of Pseudomonas aeruginosa (mutations A129C and D139C) | Descriptor: | CHLORIDE ION, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, ... | Authors: | Frere, F, Reents, H, Schubert, W.-D, Heinz, D.W, Jahn, D. | Deposit date: | 2004-08-09 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro J.Mol.Biol., 345, 2005
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1W5N
| Stepwise introduction of zinc binding site into porphobilinogen synthase of Pseudomonas aeruginosa (mutations D131C and D139C) | Descriptor: | CHLORIDE ION, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, ... | Authors: | Frere, F, Reents, H, Schubert, W.-D, Heinz, D.W, Jahn, D. | Deposit date: | 2004-08-09 | Release date: | 2005-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro J.Mol.Biol., 345, 2005
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