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1CIA
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1cia
REPLACEMENT OF CATALYTIC HISTIDINE-195 OF CHLORAMPHENICOL ACETYLTRANSFERASE: EVIDENCE FOR A GENERAL BASE ROLE FOR GLUTAMATE
Descriptor:CHLORAMPHENICOL ACETYLTRANSFERASE (TYPE III) (E.C.2.3.1.28) MUTANT WITH HIS 195 REPLACED BY GLN (H195Q) (ENGINEERED)
Authors:Leslie, A.G.W., Gibbs, M.R.
Deposit date:1993-07-19
Release date:1994-01-31
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate.
Biochemistry, 33, 1994
1CLA
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1cla
EVIDENCE FOR TRANSITION-STATE STABILIZATION BY SERINE-148 IN THE CATALYTIC MECHANISM OF CHLORAMPHENICOL ACETYLTRANSFERASE
Descriptor:TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE (CAT III) (E.C.2.3.1.28) (S148A MUTANT)-CHLORAMPHENICOL COMPLEX
Authors:Gibbs, M.R., Leslie, A.G.W.
Deposit date:1989-10-16
Release date:1990-07-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Evidence for transition-state stabilization by serine-148 in the catalytic mechanism of chloramphenicol acetyltransferase.
Biochemistry, 29, 1990
1PD5
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1pd5
CRYSTAL STRUCTURE OF E.COLI CHLORAMPHENICOL ACETYLTRANSFERASE TYPE I AT 2.5 ANGSTROM RESOLUTION
Descriptor:Chloramphenicol acetyltransferase (E.C.2.3.1.28)
Authors:Roidis, A., Kokkinidis, M.
Deposit date:2003-05-19
Release date:2004-06-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of E.coli chloramphenicol acetyltransferase type I at 2.5 Angstrom resolution
To be Published
1Q23
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1q23
CRYSTAL STRUCTURE OF CHLORAMPHENICOL ACETYLTRANSFERASE I COMPLEXED WITH FUSIDIC ACID AT 2.18 A RESOLUTION
Descriptor:Chloramphenicol acetyltransferase (E.C.2.3.1.28)
Authors:Roidis, A., Kokkinidis, M.
Deposit date:2003-07-23
Release date:2004-08-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structure of Chloramphenicol acetyltransferase I in the apoenzyme form and complexed with fusidic acid at 2.18 A resolution
To be Published
1QCA
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1qca
QUADRUPLE MUTANT Q92C, N146F, Y168F, I172V TYPE III CAT COMPLEXED WITH FUSIDIC ACID. CRYSTALS GROWN AT PH 6.3. X-RAY DATA COLLECTED AT ROOM TEMPERATURE
Descriptor:TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE, FUSIDIC ACID
Authors:Leslie, A.G.W.
Deposit date:1995-08-03
Release date:1995-10-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Steroid recognition by chloramphenicol acetyltransferase: engineering and structural analysis of a high affinity fusidic acid binding site.
J.Mol.Biol., 254, 1995
2CLA
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2cla
CRYSTAL STRUCTURE OF THE ASP-199-ASN MUTANT OF CHLORAMPHENICOL ACETYLTRANSFERASE TO 2.35 ANGSTROMS RESOLUTION. STRUCTURAL CONSEQUENCES OF DISRUPTION OF A BURIED SALT-BRIDGE
Descriptor:CHLORAMPHENICOL ACETYLTRANSFERASE (E.C.2.3.1.28) (CATIII) (D199N MUTANT)
Authors:Gibbs, M.R., Moody, P.C.E., Leslie, A.G.W.
Deposit date:1990-04-05
Release date:1990-07-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the aspartic acid-199----asparagine mutant of chloramphenicol acetyltransferase to 2.35-A resolution: structural consequences of disruption of a buried salt bridge.
Biochemistry, 29, 1990
2I9D
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2i9d
CHLORAMPHENICOL ACETYLTRANSFERASE
Descriptor:Chloramphenicol acetyltransferase
Authors:Duke, N.E.C., Li, H., Abdullah, J., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-09-05
Release date:2006-10-17
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:chloramphenicol acetyltransferase
To be Published
3CLA
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3cla
REFINED CRYSTAL STRUCTURE OF TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE AT 1.75 ANGSTROMS RESOLUTION
Descriptor:TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE (CAT III) (E.C.2.3.1.28) COMPLEX WITH CHLORAMPHENICOL
Authors:Leslie, A.G.W.
Deposit date:1990-07-09
Release date:1990-10-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Refined crystal structure of type III chloramphenicol acetyltransferase at 1.75 A resolution.
J.Mol.Biol., 213, 1990
3U9B
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3u9b
STRUCTURE OF APO-CATI
Descriptor:Chloramphenicol acetyltransferase (E.C.2.3.1.28)
Authors:Biswas, T., Garneau-Tsodikova, S., Tsodikov, O.V.
Deposit date:2011-10-18
Release date:2012-02-15
Modification date:2012-04-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structural basis for substrate versatility of chloramphenicol acetyltransferase CAT(I).
Protein Sci., 21, 2012
3U9F
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3u9f
STRUCTURE OF CATI IN COMPLEX WITH CHLORAMPHENICOL
Descriptor:Chloramphenicol acetyltransferase (E.C.2.3.1.28)
Authors:Biswas, T., Garneau-Tsodikova, S., Tsodikov, O.V.
Deposit date:2011-10-18
Release date:2012-02-15
Modification date:2012-04-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structural basis for substrate versatility of chloramphenicol acetyltransferase CAT(I).
Protein Sci., 21, 2012
4CLA
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4cla
ALTERNATIVE BINDING MODES FOR CHLORAMPHENICOL AND 1-SUBSTITUTED CHLORAMPHENICOL ANALOGUES REVEALED BY SITE-DIRECTED MUTAGENESIS AND X-RAY CRYSTALLOGRAPHY OF CHLORAMPHENICOL ACETYLTRANSFERASE
Descriptor:TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE (CAT III) (E.C.2.3.1.28) (MUTANT WITH LEU 160 REPLACED BY PHE) (L160F) COMPLEX WITH CHLORAMPHENICOL
Authors:Leslie, A.G.W.
Deposit date:1990-10-23
Release date:1992-01-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternative binding modes for chloramphenicol and 1-substituted chloramphenicol analogues revealed by site-directed mutagenesis and X-ray crystallography of chloramphenicol acetyltransferase.
Biochemistry, 30, 1991
1NOC
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1noc
MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN (DELTA 114) COMPLEXED WITH TYPE I E. COLI CHLORAMPHENICOL ACETYL TRANSFERASE AND IMIDAZOLE
Descriptor:INDUCIBLE NITRIC OXIDE SYNTHASE, TYPE 1 CHLORAMPHENICOL ACETYLTRANSFERASE, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZOLE
Authors:Crane, B.R., Arvai, A.S., Getzoff, E.D., Stuehr, D.J., Tainer, J.A.
Deposit date:1997-09-28
Release date:1998-10-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of nitric oxide synthase oxygenase domain and inhibitor complexes.
Science, 278, 1997
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