1LSL
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CRYSTAL STRUCTURE OF THE THROMBOSPONDIN-1 TYPE 1 REPEATS
Descriptor:Thrombospondin 1
Authors:Tan, K., Duquette, M., Liu, J., Dong, Y., Zhang, R., Joachimiak, A., Lawler, J., Wang, J.-H.
Deposit date:2002-05-17
Release date:2002-12-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication.
J.Cell Biol., 159, 2002
1SZL
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F-SPONDIN TSR DOMAIN 1
Descriptor:F-spondin
Authors:Tossavainen, H., Paakkonen, K., Permi, P., Kilpelainen, I., Guntert, P.
Deposit date:2004-04-06
Release date:2005-04-19
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structures of the first and fourth TSR domains of F-spondin
Proteins, 64, 2006
1VEX
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F-SPONDIN TSR DOMAIN 4
Descriptor:F-spondin
Authors:Paakkonen, K., Tossavainen, H., Permi, P., Kilpelainen, I., Guntert, P.
Deposit date:2004-04-06
Release date:2005-04-19
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structures of the first and fourth TSR domains of F-spondin
Proteins, 64, 2006
1W0R
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SOLUTION STRUCTURE OF DIMERIC FORM OF PROPERDIN BY X-RAY SOLUTION SCATTERING AND ANALYTICAL ULTRACENTRIFUGATION
Descriptor:PROPERDIN
Authors:Sun, Z., Reid, K.B.M., Perkins, S.J.
Deposit date:2004-06-11
Release date:2005-07-06
Modification date:2010-04-07
Method:SOLUTION SCATTERING
Cite:The Dimeric and Trimeric Solution Structures of the Multidomain Complement Protein Properdin by X-Ray Scattering, Analytical Ultracentrifugation and Constrained Modelling.
J.Mol.Biol., 343, 2004
1W0S
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SOLUTION STRUCTURE OF TRIMERIC FORM OF PROPERDIN BY X-RAY SOLUTION SCATTERING AND ANALYTICAL ULTRACENTRIFUGATION
Descriptor:PROPERDIN
Authors:Sun, Z., Reid, K.B.M., Perkins, S.J.
Deposit date:2004-06-11
Release date:2005-07-06
Modification date:2010-04-07
Method:SOLUTION SCATTERING
Cite:The Dimeric and Trimeric Solution Structures of the Multidomain Complement Protein Properdin by X-Ray Scattering, Analytical Ultracentrifugation and Constrained Modelling.
J.Mol.Biol., 343, 2004
3GHM
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CRYSTAL STRUCTURE OF THE EXOSITE-CONTAINING FRAGMENT OF HUMAN ADAMTS13 (FORM-1)
Descriptor:A disintegrin and metalloproteinase with thrombospondin motifs 13 (E.C.3.4.24.-)
Authors:Akiyama, M., Takeda, S., Kokame, K., Takagi, J., Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
3GHN
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CRYSTAL STRUCTURE OF THE EXOSITE-CONTAINING FRAGMENT OF HUMAN ADAMTS13 (FORM-2)
Descriptor:A disintegrin and metalloproteinase with thrombospondin motifs 13 (E.C.3.4.24.-)
Authors:Akiyama, M., Takeda, S., Kokame, K., Takagi, J., Miyata, T.
Deposit date:2009-03-04
Release date:2009-10-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
3R6B
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CRYSTAL STRUCTURE OF THROMBOSPONDIN-1 TSR DOMAINS 2 AND 3
Descriptor:Thrombospondin-1
Authors:Page, R.C., Klenotic, P.A., Misra, S., Silverstein, R.L.
Deposit date:2011-03-21
Release date:2011-08-10
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.
Protein Expr.Purif., 80, 2011
3VDJ
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CRYSTAL STRUCTURE OF CIRCUMSPOROZOITE PROTEIN ATSR DOMAIN, R32 NATIVE FORM
Descriptor:Circumsporozoite (CS) protein
Authors:Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Lu, C., Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Modification date:2012-05-30
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VDK
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CRYSTAL STRUCTURE OF CIRCUMSPOROZOITE PROTEIN ATSR DOMAIN, R32 PLATINUM-BOUND FORM
Descriptor:Circumsporozoite (CS) protein
Authors:Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Lu, C., Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Modification date:2012-05-30
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VDL
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CRYSTAL STRUCTURE OF CIRCUMSPOROZOITE PROTEIN ATSR DOMAIN, P43212 FORM
Descriptor:Circumsporozoite (CS) protein
Authors:Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Lu, C., Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Modification date:2012-05-30
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VN4
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CRYSTAL STRUCTURE OF THE EXOSITE-CONTAINING FRAGMENT OF HUMAN ADAMTS13 (P475S MUTANT)
Descriptor:A disintegrin and metalloproteinase with thrombospondin motifs 13 (E.C.3.4.24.87)
Authors:Nakayama, D., Akiyama, M., Takeda, S., Kokame, K., Takagi, J., Miyata, T.
Deposit date:2011-12-21
Release date:2012-12-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural analysis and biochemical studies of ADAMTS13 P475S mutant
To be Published
2RJQ
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CRYSTAL STRUCTURE OF ADAMTS5 WITH INHIBITOR BOUND
Descriptor:ADAMTS-5 (E.C.3.4.24.-)
Authors:Mosyak, L., Stahl, M., Somers, W.
Deposit date:2007-10-15
Release date:2007-12-11
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Protein Sci., 17, 2008
4DLO
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CRYSTAL STRUCTURE OF THE GAIN AND HORMR DOMAINS OF BRAIN ANGIOGENESIS INHIBITOR 3 (BAI3)
Descriptor:Brain-specific angiogenesis inhibitor 3
Authors:Arac, D., Boucard, A.A., Bolliger, M.F., Nguyen, J., Soltis, M., Sudhof, T.C., Brunger, A.T.
Deposit date:2012-02-06
Release date:2012-02-22
Modification date:2014-07-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.
Embo J., 31, 2012
4HQF
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM TRAP, I4 FORM
Descriptor:Thrombospondin-related anonymous protein, TRAP
Authors:Song, G., Koksal, A.C., Lu, C., Springer, T.A.
Deposit date:2012-10-25
Release date:2012-12-26
Modification date:2013-01-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
4OKR
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STRUCTURES OF TOXOPLASMA GONDII MIC2
Descriptor:Micronemal protein MIC2
Authors:Song, G., Springer, T.A.
Deposit date:2014-01-22
Release date:2014-03-19
Modification date:2014-04-23
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structures of the Toxoplasma gliding motility adhesin.
Proc.Natl.Acad.Sci.USA, 111, 2014
4OKU
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STRUCTURE OF TOXOPLASMA GONDII PROMIC2
Descriptor:Micronemal protein MIC2
Authors:Song, G., Springer, T.A.
Deposit date:2014-01-22
Release date:2014-03-19
Modification date:2014-04-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of the Toxoplasma gliding motility adhesin.
Proc.Natl.Acad.Sci.USA, 111, 2014
5FOE
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CRYSTAL STRUCTURE OF THE C. ELEGANS PROTEIN O-FUCOSYLTRANSFERASE 2 (CEPOFUT2) DOUBLE MUTANT (R298K-R299K) IN COMPLEX WITH GDP AND THE HUMAN TSR1 FROM THROMBOSPONDIN 1
Descriptor:GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, THROMBOSPONDIN-1
Authors:Valero-Gonzalez, J., Leonhard-Melief, C., Lira-Navarrete, E., Jimenez-Oses, G., Hernandez-Ruiz, C., Pallares, M.C., Yruela, I., Vasudevan, D., Lostao, A., Corzana, F., Takeuchi, H., Haltiwanger, R.S., Hurtado-Guerrero, R.
Deposit date:2015-11-19
Release date:2016-01-27
Modification date:2016-03-30
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:A Proactive Role of Water Molecules in Acceptor Recognition of Thrombospondin Type 1 Repeats by Protein-O-Fucosyltransferase 2
Nat.Chem.Biol., 12, 2016
5FTT
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OCTAMERIC COMPLEX OF LATROPHILIN 3 (LEC, OLF) , UNC5D (IG, IG2, TSP1) AND FLRT2 (LRR)
Descriptor:NETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3
Authors:Jackson, V.A., Mehmood, S., Chavent, M., Roversi, P., Carrasquero, M., del Toro, D., Seyit-Bremer, G., Ranaivoson, F.M., Comoletti, D., Sansom, M.S.P., Robinson, C.V., Klein, R., Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
3OJY
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT COMPONENT C8
Descriptor:Complement component C8 alpha chain, Complement component C8 beta chain, Complement component C8 gamma chain
Authors:Lovelace, L.L., Cooper, C.L., Sodetz, J.M., Lebioda, L.
Deposit date:2010-08-23
Release date:2011-04-13
Modification date:2014-04-16
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J.Biol.Chem., 286, 2011
3T5O
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT COMPONENT C6
Descriptor:Complement component C6
Authors:Aleshin, A.E., Stec, B., Bankston, L.A., DiScipio, R.G., Liddington, R.C.
Deposit date:2011-07-27
Release date:2012-02-01
Modification date:2012-04-11
Method:X-RAY DIFFRACTION (2.869 Å)
Cite:Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC).
J.Biol.Chem., 287, 2012
4A5W
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CRYSTAL STRUCTURE OF C5B6
Descriptor:COMPLEMENT C5, COMPLEMENT COMPONENT C6
Authors:Hadders, M.A., Bubeck, D., Forneris, F., Pangburn, M., Llorca, O., Lea, S.M., Gros, P.
Deposit date:2011-10-28
Release date:2012-03-14
Modification date:2012-10-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
4E0S
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CRYSTAL STRUCTURE OF C5B-6
Descriptor:Complement C5, Complement component C6
Authors:Aleshin, A.E., Stec, B., DiScipio, R., Liddington, R.C.
Deposit date:2012-03-05
Release date:2012-04-18
Modification date:2012-06-20
Method:X-RAY DIFFRACTION (4.21 Å)
Cite:Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.
J.Biol.Chem., 287, 2012
5FMW
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THE POLY-C9 COMPONENT OF THE COMPLEMENT MEMBRANE ATTACK COMPLEX
Descriptor:POLYC9
Authors:Dudkina, N.V., Spicer, B.A., Reboul, C.F., Conroy, P.J., Lukoyanova, N., Elmlund, H., Law, R.H.P., Ekkel, S.M., Kondos, S.C., Goode, R.J.A., Ramm, G., Whisstock, J.C., Saibil, H.R., Dunstone, M.A.
Deposit date:2015-11-10
Release date:2016-02-17
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure of the Poly-C9 Component of the Complement Membrane Attack Complex
Nat.Commun., 7, 2016
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