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4GBY
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BU of 4gby by Molmil
The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to D-xylose
Descriptor: D-xylose-proton symporter, beta-D-xylopyranose, nonyl beta-D-glucopyranoside
Authors:Sun, L.F, Zeng, X, Yan, C.Y, Yan, N.
Deposit date:2012-07-28
Release date:2012-10-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.808 Å)
Cite:Crystal structure of a bacterial homologue of glucose transporters GLUT1-4.
Nature, 490, 2012
4GBZ
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BU of 4gbz by Molmil
The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to D-glucose
Descriptor: D-xylose-proton symporter, beta-D-glucopyranose, nonyl beta-D-glucopyranoside
Authors:Sun, L.F, Zeng, X, Yan, C.Y, Yan, N.
Deposit date:2012-07-28
Release date:2012-10-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Crystal structure of a bacterial homologue of glucose transporters GLUT1-4.
Nature, 490, 2012
4GC0
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BU of 4gc0 by Molmil
The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to 6-bromo-6-deoxy-D-glucose
Descriptor: 6-bromo-6-deoxy-beta-D-glucopyranose, D-xylose-proton symporter, nonyl beta-D-glucopyranoside
Authors:Yan, N, Sun, L.F, Zeng, X, Yan, C.Y.
Deposit date:2012-07-28
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a bacterial homologue of glucose transporters GLUT1-4.
Nature, 490, 2012
4JA4
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BU of 4ja4 by Molmil
Inward open conformation of the xylose transporter XylE from E. coli
Descriptor: CADMIUM ION, D-xylose-proton symporter
Authors:Quistgaard, E.M, Low, C, Moberg, P, Tresaugues, L, Nordlund, P.
Deposit date:2013-02-18
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
Nat.Struct.Mol.Biol., 20, 2013
4JA3
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BU of 4ja3 by Molmil
Partially occluded inward open conformation of the xylose transporter XylE from E. coli
Descriptor: CADMIUM ION, D-xylose-proton symporter, LUTETIUM (III) ION
Authors:Quistgaard, E.M, Low, C, Moberg, P, Tresaugues, L, Nordlund, P.
Deposit date:2013-02-18
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
Nat.Struct.Mol.Biol., 20, 2013
4LDS
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BU of 4lds by Molmil
The inward-facing structure of the glucose transporter from Staphylococcus epidermidis
Descriptor: Glucose transporter GlcP
Authors:Choe, J, Aleshin, A, Iancu, C.V.
Deposit date:2013-06-25
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a glucose/H+ symporter and its mechanism of action.
Proc.Natl.Acad.Sci.USA, 110, 2013
4PYP
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BU of 4pyp by Molmil
Crystal structure of the human glucose transporter GLUT1
Descriptor: Solute carrier family 2, facilitated glucose transporter member 1, nonyl beta-D-glucopyranoside
Authors:Deng, D, Yan, C.Y, Xu, C, Wu, J.P, Sun, P.C, Hu, M.X, Yan, N.
Deposit date:2014-03-27
Release date:2014-05-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.166 Å)
Cite:Crystal structure of the human glucose transporter GLUT1
Nature, 510, 2014
4QIQ
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BU of 4qiq by Molmil
Crystal structure of D-xylose-proton symporter
Descriptor: D-xylose-proton symporter, ZINC ION
Authors:Wisedchaisri, G, Park, M, Iadanza, M.G, Zheng, H, Gonen, T.
Deposit date:2014-06-01
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE.
Nat Commun, 5, 2014
5C65
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BU of 5c65 by Molmil
Structure of the human glucose transporter GLUT3 / SLC2A3
Descriptor: CHOLESTEROL HEMISUCCINATE, Octyl Glucose Neopentyl Glycol, Solute carrier family 2, ...
Authors:Pike, A.C.W, Quigley, A, Chu, A, Tessitore, A, Xia, X, Mukhopadhyay, S, Wang, D, Kupinska, K, Strain-Damerell, C, Chalk, R, Burgess-Brown, N.A, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2015-06-22
Release date:2015-07-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the human glucose transporter GLUT3 / SLC2A3
To Be Published
4ZWB
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BU of 4zwb by Molmil
Crystal structure of maltose-bound human GLUT3 in the outward-occluded conformation at 2.4 angstrom
Descriptor: Solute carrier family 2, facilitated glucose transporter member 3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Deng, D, Sun, P.C, Yan, C.Y, Yan, N.
Deposit date:2015-05-19
Release date:2015-07-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
4ZWC
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BU of 4zwc by Molmil
Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ...
Authors:Deng, D, Sun, P.C, Yan, C.Y, Yan, N.
Deposit date:2015-05-19
Release date:2015-07-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
4ZW9
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BU of 4zw9 by Molmil
Crystal structure of human GLUT3 bound to D-glucose in the outward-occluded conformation at 1.5 angstrom
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ...
Authors:Deng, D, Sun, P.C, Yan, C.Y, Yan, N.
Deposit date:2015-05-19
Release date:2015-07-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
4YBQ
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BU of 4ybq by Molmil
Rat GLUT5 with Fv in the outward-open form
Descriptor: Solute carrier family 2, facilitated glucose transporter member 5, antibody Fv fragment heavy chain, ...
Authors:Nomura, N, Shimamura, T, Iwata, S.
Deposit date:2015-02-19
Release date:2015-10-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Structure and mechanism of the mammalian fructose transporter GLUT5
Nature, 526, 2015
4YB9
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BU of 4yb9 by Molmil
Crystal structure of the Bovine Fructose transporter GLUT5 in an open inward-facing conformation
Descriptor: Solute carrier family 2, facilitated glucose transporter member 5
Authors:Verdon, G, Kang, H.J, Iwata, S, Drew, D.
Deposit date:2015-02-18
Release date:2015-10-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and mechanism of the mammalian fructose transporter GLUT5.
Nature, 526, 2015
5EQG
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BU of 5eqg by Molmil
Human GLUT1 in complex with inhibitor (2~{S})-3-(4-fluorophenyl)-2-[2-(3-hydroxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide
Descriptor: (2~{S})-3-(4-fluorophenyl)-2-[2-(3-hydroxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide, Solute carrier family 2, facilitated glucose transporter member 1
Authors:Kapoor, K, Finer-Moore, J, Pedersen, B.P, Caboni, L, Waight, A.B, Hillig, R, Bringmann, P, Heisler, I, Muller, T, Siebeneicher, H, Stroud, R.M.
Deposit date:2015-11-12
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EQI
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BU of 5eqi by Molmil
Human GLUT1 in complex with Cytochalasin B
Descriptor: Cytochalasin B, Solute carrier family 2, facilitated glucose transporter member 1
Authors:Kapoor, K, Finer-Moore, J, Pedersen, B.P, Caboni, L, Waight, A.B, Hillig, R, Bringmann, P, Heisler, I, Muller, T, Siebeneicher, H, Stroud, R.M.
Deposit date:2015-11-12
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EQH
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BU of 5eqh by Molmil
Human GLUT1 in complex with inhibitor (2~{S})-3-(2-bromophenyl)-2-[2-(4-methoxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide
Descriptor: (2~{S})-3-(2-bromophenyl)-2-[2-(4-methoxyphenyl)ethanoylamino]-~{N}-[(1~{S})-1-phenylethyl]propanamide, Solute carrier family 2, facilitated glucose transporter member 1
Authors:Kapoor, K, Finer-Moore, J, Pedersen, B.P, Caboni, L, Waight, A.B, Hillig, R, Bringmann, P, Heisler, I, Muller, T, Siebeneicher, H, Stroud, R.M.
Deposit date:2015-11-12
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides.
Proc.Natl.Acad.Sci.USA, 113, 2016
6H7D
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BU of 6h7d by Molmil
Crystal Structure of A. thaliana Sugar Transport Protein 10 in complex with glucose in the outward occluded state
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, PHOSPHATE ION, ...
Authors:Pedersen, B.P, Paulsen, P.A, Custodio, T.F.
Deposit date:2018-07-31
Release date:2019-02-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the plant symporter STP10 illuminates sugar uptake mechanism in monosaccharide transporter superfamily.
Nat Commun, 10, 2019
6N3I
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BU of 6n3i by Molmil
Crystal structure of a double Trp XylE mutants (G58W/L315W)
Descriptor: D-xylose transporter
Authors:Jiang, X, Wu, J.P, Yan, N.
Deposit date:2018-11-15
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.69 Å)
Cite:Engineered XylE as a tool for mechanistic investigation and ligand discovery of the glucose transporters GLUTs.
Cell Discov, 5, 2019
6RW3
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BU of 6rw3 by Molmil
The molecular basis for sugar import in malaria parasites.
Descriptor: Hexose transporter 1, alpha-D-glucopyranose, beta-D-glucopyranose
Authors:Qureshi, A, Matsuoka, R, Brock, J, Drew, D.
Deposit date:2019-06-03
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:The molecular basis for sugar import in malaria parasites.
Nature, 578, 2020
6M2L
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BU of 6m2l by Molmil
Crystal structure of Plasmodium falciparum hexose transporter PfHT1 bound with C3361
Descriptor: (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Hexose transporter 1
Authors:Jiang, X, Yuan, Y.Y, Zhang, S, Wang, N, Yan, C.Y, Yan, N.
Deposit date:2020-02-27
Release date:2020-09-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum.
Cell, 183, 2020
6M20
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BU of 6m20 by Molmil
Crystal structure of Plasmodium falciparum hexose transporter PfHT1 bound with glucose
Descriptor: Hexose transporter 1, beta-D-glucopyranose, nonyl beta-D-glucopyranoside
Authors:Jiang, X, Yuan, Y.Y, Zhang, S, Wang, N, Yan, C.Y, Yan, N.
Deposit date:2020-02-26
Release date:2020-09-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum.
Cell, 183, 2020
6THA
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BU of 6tha by Molmil
Crystal structure of human sugar transporter GLUT1 (SLC2A1) in the inward conformation
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, Solute carrier family 2, ...
Authors:Pedersen, B.P, Paulsen, P.A, Custodio, T.F.
Deposit date:2019-11-19
Release date:2020-11-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family.
Life Sci Alliance, 4, 2021
7CRZ
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BU of 7crz by Molmil
Crystal structure of human glucose transporter GLUT3 bound with C3361
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Solute carrier family 2, ...
Authors:Yuan, Y.Y, Zhang, S, Wang, N, Jiang, X, Yan, N.
Deposit date:2020-08-14
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents.
Proc.Natl.Acad.Sci.USA, 118, 2021
7AAR
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BU of 7aar by Molmil
sugar/H+ symporter STP10 in inward open conformation
Descriptor: CHLORIDE ION, Octyl Glucose Neopentyl Glycol, Sugar transport protein 10, ...
Authors:Bavnhoej, L, Paulsen, P.A, Pedersen, B.P.
Deposit date:2020-09-04
Release date:2021-08-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Molecular mechanism of sugar transport in plants unveiled by structures of glucose/H + symporter STP10.
Nat.Plants, 7, 2021

 

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