PDB: 19 resultsInfo pagesStatus searchChemie searchBIRD

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5HDN	Crystal structure of heat shock factor1-DBD complex with ds-DNA and TtT Descriptor: CITRIC ACID, DNA (5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3'), Heat shock factor protein 1, ... Authors: Feng, H, Liu, W, Wang, D.C. Deposit date: 2016-01-05 Release date: 2017-01-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.68 Å) Cite: HSF1-DBD crystal structure To Be Published
5HDG	crystal structure of heat shock factor 1-DBD Descriptor: Heat shock factor protein 1, SODIUM ION Authors: Feng, H, Liu, W, Wang, D.C. Deposit date: 2016-01-05 Release date: 2017-01-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: HSF1-DBD crystal structure To Be Published
7DCJ	Crystal structure of HSF1 DNA-binding domain in complex with 2-site HSE DNA in the head-to-head orientation Descriptor: DNA (5'-D(*GP*CP*CP*GP*AP*AP*TP*AP*TP*TP*CP*GP*G)-3'), Heat shock factor protein 1, SODIUM ION Authors: Feng, N, Liu, W. Deposit date: 2020-10-26 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.004 Å) Cite: Structures of heat shock factor trimers bound to DNA. Iscience, 24, 2021
7DCT	Crystal structure of HSF1 DNA-binding domain in complex with 3-site HSE DNA (24 bp) Descriptor: DNA (5'-D(*AP*CP*TP*CP*GP*CP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*GP*CP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*GP*CP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*GP*CP*GP*AP*G)-3'), Heat shock factor protein 1, ... Authors: Feng, N, Liu, W. Deposit date: 2020-10-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Structures of heat shock factor trimers bound to DNA. Iscience, 24, 2021
7DCS	Crystal structure of HSF1 DNA-binding domain in complex with 3-site HSE DNA (23 bp) Descriptor: DNA (5'-D(*AP*TP*CP*CP*GP*CP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*GP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*CP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*GP*CP*GP*GP*A)-3'), Heat shock factor protein 1, ... Authors: Feng, N, Liu, W. Deposit date: 2020-10-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of heat shock factor trimers bound to DNA. Iscience, 24, 2021
5D5V	Crystal structure of human Hsf1 with Satellite III repeat DNA Descriptor: DNA, Heat shock factor protein 1, MAGNESIUM ION Authors: Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. Deposit date: 2015-08-11 Release date: 2015-12-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
5D5U	Crystal structure of human Hsf1 with HSE DNA Descriptor: Heat shock Element DNA, Heat shock factor protein 1 Authors: Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. Deposit date: 2015-08-11 Release date: 2015-12-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
5HDK	Crystal structure of heat shock factor 2-DBD Descriptor: CHLORIDE ION, Heat shock factor protein 2, POTASSIUM ION, ... Authors: Feng, H, Liu, W, Wang, D.C. Deposit date: 2016-01-05 Release date: 2017-01-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.32 Å) Cite: HSF1-DBD crystal structure To Be Published
5JCT	Crystal Structure of Human Pirin in complex with a Chemical Probe pyrrolidine 24 Descriptor: DIMETHYL SULFOXIDE, FE (III) ION, GLYCEROL, ... Authors: Ali, S, van Montfort, R. Deposit date: 2016-04-15 Release date: 2017-01-11 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen. J. Med. Chem., 60, 2017
2LDU	Solution NMR Structure of Heat shock factor protein 1 DNA binding domain from homo sapiens, Northeast Structural Genomics Consortium Target HR3023C Descriptor: Heat shock factor protein 1 Authors: Liu, G, Xiao, R, Ciccosanti, C, Janjua, H, Acton, T.B, Lee, H, Wang, H.B, Huang, Y.B, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) Deposit date: 2011-06-01 Release date: 2011-07-06 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Northeast Structural Genomics Consortium Target HR3023C To be Published
5D5W	Crystal structure of Chaetomium thermophilum Skn7 with HSE DNA Descriptor: HSE DNA, Putative transcription factor Authors: Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. Deposit date: 2015-08-11 Release date: 2015-12-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
5D5Z	Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form II Descriptor: Putative transcription factor Authors: Neudegger, T, Verghese, J, Hayer-Hartl, M, Bracher, A, Hartl, F.U. Deposit date: 2015-08-11 Release date: 2015-12-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
5D5Y	Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form I Descriptor: Putative transcription factor Authors: Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. Deposit date: 2015-08-11 Release date: 2015-12-30 Last modified: 2016-02-10 Method: X-RAY DIFFRACTION (1.03 Å) Cite: Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
5D5X	Crystal structure of Chaetomium thermophilum Skn7 with SSRE DNA Descriptor: Putative transcription factor, SSRE DNA strand 1, SSRE DNA strand 2 Authors: Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. Deposit date: 2015-08-11 Release date: 2015-12-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
5D60	Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form III Descriptor: Putative transcription factor Authors: Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. Deposit date: 2015-08-11 Release date: 2016-06-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
7DCU	Crystal structure of HSF2 DNA-binding domain in complex with 3-site HSE DNA (21 bp) Descriptor: DNA (5'-D(*AP*CP*CP*GP*CP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*GP*CP*GP*G)-3'), Heat shock factor protein 2, ... Authors: Feng, N, Liu, W. Deposit date: 2020-10-27 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structures of heat shock factor trimers bound to DNA. Iscience, 24, 2021
3CI9	Crystal Structure of the human HSBP1 Descriptor: Heat shock factor-binding protein 1 Authors: Liu, X, Xu, L, Liu, Y, Zhu, G, Zhang, X.C, Li, X, Rao, Z. Deposit date: 2008-03-11 Release date: 2009-01-20 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the hexamer of human heat shock factor binding protein 1 Proteins, 75, 2009
5D8K	Human HSF2 DNA-Binding Domain bound to 2-site HSE DNA at 1.73 Angstroms Resolution Descriptor: DNA (5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3'), Heat shock factor protein 2 Authors: Jaeger, A.M, Pemble, C.W, Thiele, D.J. Deposit date: 2015-08-17 Release date: 2016-01-06 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.728 Å) Cite: Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. Nat.Struct.Mol.Biol., 23, 2016
5D8L	Human HSF2 DNA Binding Domain in complex with 3-site HSE DNA at 2.1 Angstroms Resolution Descriptor: DNA (5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3'), Heat shock factor protein 2 Authors: Jaeger, A.M, Pemble, C.W, Thiele, D.J. Deposit date: 2015-08-17 Release date: 2016-01-06 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.069 Å) Cite: Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. Nat.Struct.Mol.Biol., 23, 2016