Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6H0Q
DownloadVisualize
BU of 6h0q by Molmil
B1-type ACP domain from module 7 of MLSB
Descriptor: Type I modular polyketide synthase
Authors:Moretto, L, Heylen, R, Holroyd, N, Vance, S, Broadhurst, R.W.
Deposit date:2018-07-10
Release date:2019-03-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold.
Sci Rep, 9, 2019
6H0J
DownloadVisualize
BU of 6h0j by Molmil
A1-type ACP domain from module 5 of MLSA1
Descriptor: Type I modular polyketide synthase
Authors:Moretto, L, Heylen, R, Holroyd, N, Vance, S, Broadhurst, R.W.
Deposit date:2018-07-09
Release date:2019-03-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold.
Sci Rep, 9, 2019
4PNC
DownloadVisualize
BU of 4pnc by Molmil
E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH INHIBITOR 7-METHOXY-2-METHYLEN-3,4-DIHYDRONAPHTHALEN-1(2H)-ONE
Descriptor: (2S)-7-methoxy-2-methyl-3,4-dihydronaphthalen-1(2H)-one, COBALT (II) ION, Methionine aminopeptidase, ...
Authors:Scheidig, A.J, Altmeyer, M, Klein, C.D.
Deposit date:2014-05-23
Release date:2014-07-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Beta-aminoketones as prodrugs for selective irreversible inhibitors of type-1 methionine aminopeptidases.
Bioorg.Med.Chem.Lett., 24, 2014
1YTZ
DownloadVisualize
BU of 1ytz by Molmil
Crystal structure of skeletal muscle troponin in the Ca2+-activated state
Descriptor: ALPHA-[4-(1,1,3,3 - TETRAMETHYLBUTYL)PHENYL]-OMEGA-HYDROXY-POLY(OXY-1,2-ETHANEDIYL), CALCIUM ION, Troponin C, ...
Authors:Vinogradova, M.V, Stone, D.B, Malanina, G.G, Karatzaferi, C, Cooke, R, Mendelson, R.A, Fletterick, R.J.
Deposit date:2005-02-11
Release date:2005-04-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ca2+-regulated structural changes in troponin
Proc.Natl.Acad.Sci.Usa, 102, 2005
2WI4
DownloadVisualize
BU of 2wi4 by Molmil
Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone
Descriptor: 4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine, HEAT SHOCK PROTEIN, HSP 90-ALPHA
Authors:Brough, P.A, Barril, X, Borgognoni, J, Chene, P, Davies, N.G.M, Davis, B, Drysdale, M.J, Dymock, B, Eccles, S.A, Garcia-Echeverria, C, Fromont, C, Hayes, A, Hubbard, R.E, Jordan, A.M, Rugaard-Jensen, M, Massey, A, Merret, A, Padfield, A, Parsons, R, Radimerski, T, Raynaud, F.I, Robertson, A, Roughley, S.D, Schoepfer, J, Simmonite, H, Surgenor, A, Valenti, M, Walls, S, Webb, P, Wood, M, Workman, P, Wright, L.M.
Deposit date:2009-05-08
Release date:2009-07-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Combining Hit Identification Strategies: Fragment- Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-D]Pyrimidine Inhibitors of the Hsp90 Molecular Chaperone.
J.Med.Chem., 52, 2009
4PBT
DownloadVisualize
BU of 4pbt by Molmil
Crystal structure of the M. jannaschii G2 tRNA synthetase variant bound to 4-trans-cyclooctene-amidopheylalanine (Tco-amF)
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 4-{[(1R,4E)-cyclooct-4-en-1-ylcarbonyl]amino}-L-phenylalanine, GLYCEROL, ...
Authors:Cooley, R.B, Karplus, P.A, Mehl, R.A.
Deposit date:2014-04-13
Release date:2014-07-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Gleaning Unexpected Fruits from Hard-Won Synthetases: Probing Principles of Permissivity in Non-canonical Amino Acid-tRNA Synthetases.
Chembiochem, 15, 2014
3CQ8
DownloadVisualize
BU of 3cq8 by Molmil
Ternary complex of the L415F mutant RB69 exo(-)polymerase
Descriptor: CALCIUM ION, DNA (5'-D(*DAP*DCP*DAP*DGP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*DCP*DC)-3'), ...
Authors:Zhong, X, Pedersen, L.C, Kunkel, T.A.
Deposit date:2008-04-02
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity.
Nucleic Acids Res., 36, 2008
8BEO
DownloadVisualize
BU of 8beo by Molmil
Crystal structure of E. coli glyoxylate carboligase mutant I393A with MAP
Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE, ...
Authors:Shaanan, B, Binshtein, E.
Deposit date:2022-10-21
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure of E. coli glyoxylate carboligase mutant I393A with MAP
To Be Published
1GNW
DownloadVisualize
BU of 1gnw by Molmil
STRUCTURE OF GLUTATHIONE S-TRANSFERASE
Descriptor: GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE
Authors:Reinemer, P, Prade, L, Hof, P, Neuefeind, T, Huber, R, Palme, K, Bartunik, H.D, Bieseler, B.
Deposit date:1996-09-15
Release date:1997-09-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structure of glutathione S-transferase from Arabidopsis thaliana at 2.2 A resolution: structural characterization of herbicide-conjugating plant glutathione S-transferases and a novel active site architecture.
J.Mol.Biol., 255, 1996
1Q82
DownloadVisualize
BU of 1q82 by Molmil
Crystal Structure of CC-Puromycin bound to the A-site of the 50S ribosomal subunit
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structural Insights Into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
5TW1
DownloadVisualize
BU of 5tw1 by Molmil
Crystal structure of a Mycobacterium smegmatis transcription initiation complex with RbpA
Descriptor: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ...
Authors:Hubin, E.A, Darst, S.A, Campbell, E.A.
Deposit date:2016-11-10
Release date:2017-01-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA.
Elife, 6, 2017
5ZMD
DownloadVisualize
BU of 5zmd by Molmil
Crystal structure of FTO in complex with m6dA modified ssDNA
Descriptor: Alpha-ketoglutarate-dependent dioxygenase FTO, DNA (5'-D(P*TP*CP*TP*(6MA)P*TP*AP*TP*CP*G)-3'), MANGANESE (II) ION, ...
Authors:Zhang, X, Wei, L.H, Luo, J, Xiao, Y, Liu, J, Zhang, W, Zhang, L, Jia, G.F.
Deposit date:2018-04-02
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
1K6S
DownloadVisualize
BU of 1k6s by Molmil
STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH A PHENYLBORONIC ACID
Descriptor: 4-IODO-ACETAMIDO PHENYLBORONIC ACID, Beta-lactamase PSE-2, CALCIUM ION, ...
Authors:Kerff, F, Fonze, E, Sauvage, E, Frere, J.M, Charlier, P.
Deposit date:2001-10-17
Release date:2003-06-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:CRYSTAL STRUCTURE OF CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH DIFFERENT SUBSTRATES AND ONE INHIBITOR.
To be Published
6UQK
DownloadVisualize
BU of 6uqk by Molmil
Cryo-EM structure of type 3 IP3 receptor revealing presence of a self-binding peptide
Descriptor: ZINC ION, inositol 1,4,5-triphosphate receptor, type 3
Authors:Azumaya, C.M, Linton, E.A, Risener, C.J, Nakagawa, T, Karakas, E.
Deposit date:2019-10-20
Release date:2020-01-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist.
J.Biol.Chem., 295, 2020
4C1R
DownloadVisualize
BU of 4c1r by Molmil
Bacteroides thetaiotaomicron VPI-5482 mannosyl-6-phosphatase Bt3783
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, MANNOSYL-6-PHOSPHATASE
Authors:Cuskin, F, Lowe, E.C, Zhu, Y, Temple, M, Thompson, A.J, Cartmell, A, Piens, K, Bracke, D, Vervecken, W, Munoz-Munoz, J.L, Suits, M.D.L, Boraston, A.B, Williams, S.J, Davies, G.J, Abbott, W.D, Martens, E.C, Gilbert, H.J.
Deposit date:2013-08-13
Release date:2013-11-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human Gut Bacteroidetes Can Utilize Yeast Mannan Through a Selfish Mechanism.
Nature, 517, 2015
6CCE
DownloadVisualize
BU of 6cce by Molmil
Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Kanglemycin A
Descriptor: 1,2-ETHANEDIOL, DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2018-02-07
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
6CCV
DownloadVisualize
BU of 6ccv by Molmil
Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Rifampicin
Descriptor: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2018-02-07
Release date:2018-08-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon