PDB: 13 resultsInfo pagesStatus searchChemie searchBIRD

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7LMK	Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3 Descriptor: DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION Authors: Ren, W, Song, J. Deposit date: 2021-02-05 Release date: 2021-02-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.647 Å) Cite: DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation. Nat Commun, 12, 2021
7LMM	Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2 Descriptor: DNA (cytosine-5)-methyltransferase 1,DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION Authors: Ren, W, Song, J. Deposit date: 2021-02-05 Release date: 2021-02-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.798 Å) Cite: DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation. Nat Commun, 12, 2021
3QBY	Crystal structure of the PWWP domain of human Hepatoma-derived growth factor 2 Descriptor: H4K20me3 Histone H4 Peptide, Hepatoma-derived growth factor-related protein 2, SULFATE ION, ... Authors: Zeng, H, Tempel, W, Amaya, M.F, Adams-Cioaba, M.A, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) Deposit date: 2011-01-14 Release date: 2011-02-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural and Histone Binding Ability Characterizations of Human PWWP Domains. Plos One, 6, 2011
8SIY	Origin Recognition Complex Associated (ORCA) protein bound to H4K20me3-nucleosome Descriptor: Histone H2A, Histone H2B, Histone H3.2, ... Authors: Bleichert, F, Ekundayo, B.E. Deposit date: 2023-04-17 Release date: 2023-08-02 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin. Embo J., 42, 2023
5Y5W	Crystal structure of human Spindlin1 in complex with a histone H4K20(me3) peptide Descriptor: Histone peptide H4K20(me3), Spindlin-1 Authors: Wang, C, Zang, J. Deposit date: 2017-08-10 Release date: 2017-10-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail FEBS Lett., 592, 2018
6BPH	Crystal structure of the chromodomain of RBBP1 Descriptor: AT-rich interactive domain-containing protein 4A, UNKNOWN ATOM OR ION Authors: Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2017-11-23 Release date: 2017-12-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure of chromo barrel domain of RBBP1. Biochem. Biophys. Res. Commun., 496, 2018
2QQR	JMJD2A hybrid tudor domains Descriptor: JmjC domain-containing histone demethylation protein 3A, SULFATE ION Authors: Lee, J, Botuyan, M.V, Mer, G. Deposit date: 2007-07-26 Release date: 2007-12-11 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat.Struct.Mol.Biol., 15, 2008
2QQS	JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide Descriptor: JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE Authors: Lee, J, Botuyan, M.V, Mer, G. Deposit date: 2007-07-26 Release date: 2007-12-11 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.82 Å) Cite: Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat.Struct.Mol.Biol., 15, 2008
5CPR	The novel SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity Descriptor: 6,7-dichloro-N-cyclopentyl-4-(pyridin-4-yl)phthalazin-1-amine, Histone-lysine N-methyltransferase SUV420H1, S-ADENOSYLMETHIONINE, ... Authors: Jakob, C.G, Upadhyay, A.K, Sun, C. Deposit date: 2015-07-21 Release date: 2017-01-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.22 Å) Cite: The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity. Nat. Chem. Biol., 13, 2017
6L87	Solution structure of the tandem PWWP-ARID domains of human RBBP1 Descriptor: AT-rich interactive domain-containing protein 4A Authors: Gong, W.B, Perrett, S, Feng, Y.G. Deposit date: 2019-11-05 Release date: 2021-01-06 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structural insight into chromatin recognition by multiple domains of the tumor suppressor RBBP1. J.Mol.Biol., 2021
8T9F	Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1 Descriptor: DNA (122-MER), Histone H2A.Z, Histone H2B 1.1, ... Authors: Abini-Agbomson, S, Armache, K.-J. Deposit date: 2023-06-23 Release date: 2023-09-06 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. Mol.Cell, 83, 2023
8THU	Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1 Descriptor: DNA (145-MER), DNA (146-MER), Histone H2A.Z, ... Authors: Abini-Agbomson, S, Armache, K.-J. Deposit date: 2023-07-18 Release date: 2023-09-06 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. Mol.Cell, 83, 2023
2L89	Solution structure of Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA Descriptor: PWWP domain-containing protein 1 Authors: Qiu, Y, Zhang, J, Zhang, W. Deposit date: 2011-01-07 Release date: 2011-12-21 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Solution structure of Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA Biochem.J., 2011