2QQS
JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide
Summary for 2QQS
Entry DOI | 10.2210/pdb2qqs/pdb |
Related | 2QQR |
Descriptor | JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE (3 entities in total) |
Functional Keywords | histone lysine demethylase, metal binding protein, protein-methylated peptide complex, chromatin regulator, dioxygenase, host-virus interaction, iron, metal-binding, nucleus, oxidoreductase, phosphorylation, polymorphism, transcription, transcription regulation, zinc, zinc-finger |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: O75164 |
Total number of polymer chains | 4 |
Total formula weight | 29650.96 |
Authors | Lee, J.,Botuyan, M.V.,Mer, G. (deposition date: 2007-07-26, release date: 2007-12-11, Last modification date: 2023-08-30) |
Primary citation | Lee, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat.Struct.Mol.Biol., 15:109-111, 2008 Cited by PubMed: 18084306DOI: 10.1038/nsmb1326 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.82 Å) |
Structure validation
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