PDB: 14 resultsInfo pagesStatus searchChemie searchBIRD

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6RYU	Nucleosome-CHD4 complex structure (two CHD4 copies) Descriptor: Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... Authors: Farnung, L, Ochmann, M, Cramer, P. Deposit date: 2019-06-12 Release date: 2020-07-15 Method: ELECTRON MICROSCOPY (4 Å) Cite: Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
8D4Y	C-terminal SANT-SLIDE domain of human Chromodomain-helicase-DNA-binding protein 4 (CHD4) Descriptor: Chromodomain-helicase-DNA-binding protein 4 Authors: Moghaddas Sani, H, Deshpande, C.N, Panjikar, S, Patel, K, Mackay, J.P. Deposit date: 2022-06-03 Release date: 2022-12-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families. Nat Commun, 13, 2022
2N5N	Structure of an N-terminal domain of CHD4 Descriptor: Chromodomain-helicase-DNA-binding protein 4 Authors: Silva, A.P.G, Mackay, J.P. Deposit date: 2015-07-22 Release date: 2015-11-18 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose). J.Biol.Chem., 291, 2016
2L75	Solution structure of CHD4-PHD2 in complex with H3K9me3 Descriptor: 14-meric peptide from 1Histone H3.1, Chromodomain-helicase-DNA-binding protein 4, ZINC ION Authors: Mansfield, R.E, Kwan, A.H, Mackay, J.P. Deposit date: 2010-12-02 Release date: 2011-01-19 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9 J.Biol.Chem., 286, 2011
6RYR	Nucleosome-CHD4 complex structure (single CHD4 copy) Descriptor: Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... Authors: Farnung, L, Ochmann, M, Cramer, P. Deposit date: 2019-06-11 Release date: 2020-07-15 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
2L5U	Structure of the first PHD finger (PHD1) from CHD4 (Mi2b) Descriptor: Chromodomain-helicase-DNA-binding protein 4, ZINC ION Authors: Mansfield, R.E, Kwan, A.H, Mackay, J.P. Deposit date: 2010-11-08 Release date: 2011-01-19 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9 J.Biol.Chem., 286, 2011
4O9I	Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding Descriptor: Chromodomain-helicase-DNA-binding protein 4 Authors: Wiggs, K.R, Chruszcz, M, Su, X, Minor, W, Khorasanizadeh, S. Deposit date: 2014-01-02 Release date: 2015-07-08 Last modified: 2022-04-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding TO BE PUBLISHED
6WMI	ZNF410 zinc fingers 1-5 with 17 mer blunt DNA Oligonucleotide Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*CP*AP*TP*CP*CP*CP*AP*TP*AP*AP*TP*AP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*TP*AP*TP*GP*GP*GP*AP*TP*GP*TP*G)-3'), ... Authors: Ren, R, Horton, J.R, Cheng, X. Deposit date: 2020-04-21 Release date: 2020-12-09 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.75 Å) Cite: ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression. Mol.Cell, 81, 2021
6Q3M	Structure of CHD4 PHD2 - tandem chromodomains Descriptor: 1,2-ETHANEDIOL, Chromodomain-helicase-DNA-binding protein 4, DI(HYDROXYETHYL)ETHER, ... Authors: Alt, A, Mancini, E.J. Deposit date: 2018-12-04 Release date: 2019-12-25 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Structure of histone readers To Be Published
6BGG	Solution NMR structures of the BRD3 ET domain in complex with a CHD4 peptide Descriptor: Bromodomain-containing protein 3, CHD4 Authors: Wai, D.C.C, Szyszka, T.N, Campbell, A.E, Kwong, C, Wilkinson-White, L, Silva, A.P.G, Low, J.K.K, Kwan, A.H, Gamsjaeger, R, Lu, B, Vakoc, C.R, Blobel, G.A, Mackay, J.P. Deposit date: 2017-10-28 Release date: 2018-03-21 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators. J. Biol. Chem., 293, 2018
2EE1	Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4 Descriptor: Chromodomain helicase-DNA-binding protein 4 Authors: Sato, M, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-02-15 Release date: 2007-08-21 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4 To be Published
1MM3	Solution structure of the 2nd PHD domain from Mi2b with C-terminal loop replaced by corresponding loop from WSTF Descriptor: Mi2-beta(Chromodomain helicase-DNA-binding protein 4) and transcription factor WSTF, ZINC ION Authors: Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P. Deposit date: 2002-09-02 Release date: 2003-07-22 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Engineering a Protein Scaffold from a PHD Finger structure, 11, 2003
1MM2	Solution structure of the 2nd PHD domain from Mi2b Descriptor: Mi2-beta, ZINC ION Authors: Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P. Deposit date: 2002-09-02 Release date: 2003-07-22 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Engineering a Protein Scaffold from a PHD Finger structure, 11, 2003
7X73	Structure of G9a in complex with RK-701 Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase EHMT2, ... Authors: Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Shirouzu, M, Umehara, T. Deposit date: 2022-03-09 Release date: 2022-12-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.49 Å) Cite: A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression. Nat Commun, 14, 2023