2L75

Solution structure of CHD4-PHD2 in complex with H3K9me3

Summary for 2L75

• Entry DOI: 10.2210/pdb2l75/pdb
• NMR Information: BMRB: 17344
• Descriptor: Chromodomain-helicase-DNA-binding protein 4, 14-meric peptide from 1Histone H3.1, ZINC ION (3 entities in total)
• Functional Keywords: chd4, mi2b, phd2, h3k9me3, transcription-nuclear protein complex, transcription/nuclear protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 8391.40

Authors

Mansfield, R.E.,Kwan, A.H.,Mackay, J.P. (deposition date: 2010-12-02, release date: 2011-01-19, Last modification date: 2023-06-14)

• Primary citation: Mansfield, R.E.,Musselman, C.A.,Kwan, A.H.,Oliver, S.S.,Garske, A.L.,Davrazou, F.,Denu, J.M.,Kutateladze, T.G.,Mackay, J.P.; Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9; J.Biol.Chem., 286:11779-11791, 2011; PubMed: 21278251; DOI: 10.1074/jbc.M110.208207

Experimental method

SOLUTION NMR