Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5FR6
DownloadVisualize
BU of 5fr6 by Molmil
The structure of polycomb ULD complex
Descriptor: POLYCOMB COMPLEX PROTEIN BMI-1
Authors:Gray, F, Cho, H.J, Cierpicki, T.
Deposit date:2015-12-15
Release date:2016-11-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Bmi1 Regulates Prc1 Architecture and Activity Through Homo-and Hetero-Oligomerization
Nat.Commun., 7, 2016
3RPG
DownloadVisualize
BU of 3rpg by Molmil
Bmi1/Ring1b-UbcH5c complex structure
Descriptor: E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, Ubiquitin-conjugating enzyme E2 D3, ...
Authors:Bentley, M.L, Dong, K.C, Cochran, A.G.
Deposit date:2011-04-26
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6485 Å)
Cite:Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex.
Embo J., 30, 2011
2NA1
DownloadVisualize
BU of 2na1 by Molmil
ULD complex
Descriptor: Polycomb complex protein BMI-1, Polyhomeotic-like 2
Authors:Cierpicki, T, Gray, F, Cho, H.
Deposit date:2015-12-17
Release date:2016-11-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization.
Nat Commun, 7, 2016
2CKL
DownloadVisualize
BU of 2ckl by Molmil
Ring1b-Bmi1 E3 catalytic domain structure
Descriptor: IODIDE ION, POLYCOMB GROUP RING FINGER PROTEIN 4, UBIQUITIN LIGASE PROTEIN RING2, ...
Authors:Buchwald, G, van der Stoop, P, Weichenrieder, O, Perrakis, A, van Lohuizen, M, Sixma, T.K.
Deposit date:2006-04-20
Release date:2006-05-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and E3-Ligase Activity of the Ring-Ring Complex of Polycomb Proteins Bmi1 and Ring1B.
Embo J., 25, 2006
6WI7
DownloadVisualize
BU of 6wi7 by Molmil
RING1B-BMI1 fusion in closed conformation
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1 chimera, ...
Authors:Cho, H.J, Cierpicki, T.
Deposit date:2020-04-08
Release date:2021-04-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain.
Nat.Chem.Biol., 17, 2021
4S3O
DownloadVisualize
BU of 4s3o by Molmil
PCGF5-RING1B-UbcH5c complex
Descriptor: E3 ubiquitin-protein ligase RING2, Polycomb group RING finger protein 5, Ubiquitin-conjugating enzyme E2 D3, ...
Authors:Taherbhoy, A.M, Cochran, A.G.
Deposit date:2015-03-23
Release date:2015-07-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase.
Nat Commun, 6, 2015
6WI8
DownloadVisualize
BU of 6wi8 by Molmil
Inhibitor compound-induced confrontational change in Ring1b-Bmi1 domain structure
Descriptor: E3 ubiquitin-protein ligase RING2,Polycomb complex protein BMI-1 chimera, ZINC ION
Authors:Cho, H.J, Cierpicki, T.
Deposit date:2020-04-09
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.092 Å)
Cite:Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain.
Nat.Chem.Biol., 17, 2021
4R8P
DownloadVisualize
BU of 4r8p by Molmil
Crystal structure of the Ring1B/Bmi1/UbcH5c PRC1 ubiquitylation module bound to the nucleosome core particle
Descriptor: DNA (147-mer), E3 ubiquitin-protein ligase RING2, Ubiquitin-conjugating enzyme E2 D3, ...
Authors:McGinty, R.K, Henrici, R.C, Tan, S.
Deposit date:2014-09-02
Release date:2014-11-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2846 Å)
Cite:Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome.
Nature, 514, 2014
5Y53
DownloadVisualize
BU of 5y53 by Molmil
Crystal structure of AL2 PAL domain in complex with AtBMI1b binding site
Descriptor: AtBMI1b binding site, PHD finger protein ALFIN-LIKE 2
Authors:Peng, L, Wang, L.L, Huang, Y.
Deposit date:2017-08-07
Release date:2018-08-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
7ND1
DownloadVisualize
BU of 7nd1 by Molmil
First-in-class small molecule inhibitors of Polycomb Repressive Complex 1 (PRC1) RING domain
Descriptor: 3-(2-chlorophenyl)-4-ethyl-5-(1~{H}-indol-4-yl)-1~{H}-pyrrole-2-carboxylic acid, E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, ...
Authors:Cierpicki, T, Lund, G, Jaremko, L.
Deposit date:2021-01-29
Release date:2021-06-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain.
Nat.Chem.Biol., 17, 2021
8PP7
DownloadVisualize
BU of 8pp7 by Molmil
human RYBP-PRC1 bound to mononucleosome
Descriptor: DNA (215-mer), E3 ubiquitin-protein ligase RING2, Histone H2A, ...
Authors:Ciapponi, M, Benda, C, Mueller, J.
Deposit date:2023-07-06
Release date:2024-03-27
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1.
Nat.Struct.Mol.Biol., 31, 2024
5XVW
DownloadVisualize
BU of 5xvw by Molmil
Crystal structure of AL2 PAL domain in complex with AtRing1a distal site
Descriptor: AtRing1a distal binding site, PHD finger protein ALFIN-LIKE 2
Authors:Peng, L, Wang, L.L, Huang, Y.
Deposit date:2017-06-28
Release date:2018-07-04
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
2DJB
DownloadVisualize
BU of 2djb by Molmil
Solution structure of the RING domain of the human Polycomb group RING finger protein 6
Descriptor: Polycomb group RING finger protein 6, ZINC ION
Authors:Miyamoto, K, Kigawa, T, Sato, M, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-31
Release date:2007-03-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the RING domain of the human Polycomb group RING finger protein 6
To be Published
8GRM
DownloadVisualize
BU of 8grm by Molmil
Cryo-EM structure of PRC1 bound to H2AK119-UbcH5b-Ub nucleosome
Descriptor: COMMD3 protein, DNA (144-MER), DNA (145-MER), ...
Authors:Ai, H.S, Zebin, T, Zhihend, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L.
Deposit date:2022-09-02
Release date:2023-04-12
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
7JZV
DownloadVisualize
BU of 7jzv by Molmil
Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome
Descriptor: BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ...
Authors:Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E.
Deposit date:2020-09-02
Release date:2021-02-17
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Nat.Struct.Mol.Biol., 28, 2021
5XVL
DownloadVisualize
BU of 5xvl by Molmil
Crystal structure of AL2 PAL domain
Descriptor: PHD finger protein ALFIN-LIKE 2, SULFATE ION
Authors:Peng, L, Wang, L.L, Huang, Y.
Deposit date:2017-06-28
Release date:2018-07-04
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.629 Å)
Cite:Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
5XVJ
DownloadVisualize
BU of 5xvj by Molmil
Crystal structure of AL7 PAL domain
Descriptor: PHD finger protein ALFIN-LIKE 7, SULFATE ION
Authors:Peng, L, Wang, L.L, Huang, Y.
Deposit date:2017-06-28
Release date:2018-07-04
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
5Y21
DownloadVisualize
BU of 5y21 by Molmil
Crystal structure of AL2 PAL domain in complex with AtRing1a proximal site
Descriptor: AtRing1a proximal binding site peptide, PHD finger protein ALFIN-LIKE 2
Authors:Peng, L, Wang, L.L, Huang, Y.
Deposit date:2017-07-22
Release date:2018-07-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.769 Å)
Cite:Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
4HPM
DownloadVisualize
BU of 4hpm by Molmil
PCGF1 Ub fold (RAWUL)/BCORL1 PUFD Complex
Descriptor: BCL-6 corepressor-like protein 1, PHOSPHATE ION, Polycomb group RING finger protein 1
Authors:Junco, S.E, Wang, R, Gaipa, J, Taylor, A.B, Gearhart, M.D, Bardwell, V.J, Hart, P.J, Kim, C.A.
Deposit date:2012-10-24
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of the Polycomb Group Protein PCGF1 in Complex with BCOR Reveals Basis for Binding Selectivity of PCGF Homologs.
Structure, 21, 2013
4HPL
DownloadVisualize
BU of 4hpl by Molmil
PCGF1 Ub fold (RAWUL)/BCOR PUFD Complex
Descriptor: BCL-6 corepressor, Polycomb group RING finger protein 1
Authors:Junco, S.E, Wang, R, Gaipa, J, Taylor, A.B, Gearhart, M.D, Bardwell, V.J, Hart, P.J, Kim, C.A.
Deposit date:2012-10-24
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Polycomb Group Protein PCGF1 in Complex with BCOR Reveals Basis for Binding Selectivity of PCGF Homologs.
Structure, 21, 2013

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon