2CKL

Ring1b-Bmi1 E3 catalytic domain structure

Summary for 2CKL

Entry DOI	10.2210/pdb2ckl/pdb
Descriptor	POLYCOMB GROUP RING FINGER PROTEIN 4, UBIQUITIN LIGASE PROTEIN RING2, ZINC ION, ... (5 entities in total)
Functional Keywords	bmi1, ligase, ring1b, polycomb, e3-ligase, nuclear protein, chromosomal protein, transcription regulation, metal-binding, proto-oncogene, chromatin regulator, ubl conjugation pathway, repressor, zinc-finger, ring domain, transcription, transcription regulation complex
Biological source	MUS MUSCULUS (MOUSE) More
Cellular location	Nucleus: P25916 Q9CQJ4
Total number of polymer chains	2
Total formula weight	31768.75
Authors	Buchwald, G.,van der Stoop, P.,Weichenrieder, O.,Perrakis, A.,van Lohuizen, M.,Sixma, T.K. (deposition date: 2006-04-20, release date: 2006-05-11, Last modification date: 2011-07-13)
Primary citation	Buchwald, G.,Van Der Stoop, P.,Weichenrieder, O.,Perrakis, A.,Van Lohuizen, M.,Sixma, T.K. Structure and E3-Ligase Activity of the Ring-Ring Complex of Polycomb Proteins Bmi1 and Ring1B. Embo J., 25:2465-, 2006 Cited by PubMed: 16710298 DOI: 10.1038/SJ.EMBOJ.7601144 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation