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7Q33
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Solution structure of RBM39 RRM2 bound to 5'-AGCUUUG-3
Descriptor: RNA (5'-R(*AP*GP*CP*UP*UP*UP*G)-3'), RNA-binding protein 39
Authors:Campagne, S, Allain, F.H.
Deposit date:2021-10-26
Release date:2023-02-08
Last modified:2023-09-20
Method:SOLUTION NMR
Cite:Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
Nat Commun, 14, 2023
7PY2
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BU of 7py2 by Molmil
Structure of pathological TDP-43 filaments from ALS with FTLD
Descriptor: TAR DNA-binding protein 43
Authors:Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2022-01-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of pathological TDP-43 filaments from ALS with FTLD.
Nature, 601, 2022
7PU5
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Structure of SFPQ-NONO complex
Descriptor: MAGNESIUM ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ...
Authors:Fribourg, S.
Deposit date:2021-09-28
Release date:2022-03-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Crystal structure of SFPQ-NONO heterodimer.
Biochimie, 198, 2022
7PDV
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BU of 7pdv by Molmil
Crystal structure of RBM5 RRM1-zinc finger in complex with RNA
Descriptor: RNA (5'-R(P*UP*GP*GP*CP*UP*CP*UP*UP*CP*U)-3'), RNA binding motif protein 5 isoform 1, ZINC ION
Authors:Soni, K, Jagtap, P.K.A, Sattler, M.
Deposit date:2021-08-08
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Nat Commun, 14, 2023
7PCV
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Crystal structure of RBM5 RRM1-zinc finger
Descriptor: RNA-binding protein 5, ZINC ION
Authors:Soni, K, Jagtap, P.K.A, Sattler, M.
Deposit date:2021-08-04
Release date:2022-08-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for specific RNA recognition by the alternative splicing factor RBM5.
Nat Commun, 14, 2023
7OQE
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BU of 7oqe by Molmil
Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A), Cold sensitive U2 snRNA suppressor 1, ...
Authors:Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R.
Deposit date:2021-06-03
Release date:2021-08-11
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
7OQC
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The U1 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A), Pre-mRNA-processing factor 39, ...
Authors:Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R.
Deposit date:2021-06-03
Release date:2021-08-11
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
7OQB
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The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)
Descriptor: ACT1 pre-mRNA (delta-BS-A), Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing ATP-dependent RNA helicase PRP5, ...
Authors:Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R.
Deposit date:2021-06-03
Release date:2021-08-11
Last modified:2021-09-22
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
7ONB
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Structure of the U2 5' module of the A3'-SSA complex
Descriptor: MINX, PHD finger-like domain-containing protein 5A, RNU2, ...
Authors:Cretu, C, Pena, V.
Deposit date:2021-05-25
Release date:2021-08-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
7OHX
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BU of 7ohx by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL34 expression shut down, population A
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHW
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BU of 7ohw by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut down, population B
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHV
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BU of 7ohv by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL2 expression shut down, population C
Descriptor: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHS
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BU of 7ohs by Molmil
Nog1-TAP associated immature ribosomal particle population F from S. cerevisiae
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (4.38 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHR
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BU of 7ohr by Molmil
Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae
Descriptor: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-10
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (4.72 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHQ
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BU of 7ohq by Molmil
Nog1-TAP associated immature ribosomal particle population C from S. cerevisiae
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHP
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BU of 7ohp by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut down, population A
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OCX
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BU of 7ocx by Molmil
Crystal Structure of the PID-3 TOFU-6 RRM domain complex
Descriptor: Embryonic developmental protein tofu-6, Protein pid-3
Authors:Basquin, J, Ketting, R.F, Falk, S.
Deposit date:2021-04-28
Release date:2021-08-25
Last modified:2021-10-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans .
Genes Dev., 35, 2021
7NAC
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BU of 7nac by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model
Descriptor: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-21
Release date:2022-11-09
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7MI2
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BU of 7mi2 by Molmil
Seb1-G476S RNA binding domain
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Rpb7-binding protein seb1
Authors:Jacewicz, A, Shuman, S.
Deposit date:2021-04-16
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LRU
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BU of 7lru by Molmil
Crystal structure of SFPQ-NONO-SFPQ chimeric protein homodimer
Descriptor: Splicing factor, proline- and glutamine-rich,Isoform 2 of Non-POU domain-containing octamer-binding protein,Isoform Short of Splicing factor, proline- and glutamine-rich
Authors:Marshall, A.C, Bond, C.S, Mohnen, I, Knott, G.J.
Deposit date:2021-02-17
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of SFPQ-NONO-SFPQ chimeric protein homodimer
To Be Published
7LRQ
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BU of 7lrq by Molmil
Crystal structure of human SFPQ/NONO heterodimer, conserved DBHS region
Descriptor: CHLORIDE ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ...
Authors:Marshall, A.C, Bond, C.S, Mohnen, I.
Deposit date:2021-02-17
Release date:2021-05-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains.
J.Biol.Chem., 298, 2022
7LMB
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BU of 7lmb by Molmil
Tetrahymena telomerase T5D5 structure at 3.8 Angstrom
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J.
Deposit date:2021-02-05
Release date:2021-05-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of telomerase at several steps of telomere repeat synthesis.
Nature, 593, 2021
7LMA
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BU of 7lma by Molmil
Tetrahymena telomerase T3D2 structure at 3.3 Angstrom
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J.
Deposit date:2021-02-05
Release date:2021-05-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of telomerase at several steps of telomere repeat synthesis.
Nature, 593, 2021
7LHX
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BU of 7lhx by Molmil
Human U1A protein with F37M and F77M mutations for improved phasing
Descriptor: ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ...
Authors:Jenkins, J.L, Lippa, G.M, Wedekind, J.E.
Deposit date:2021-01-26
Release date:2021-03-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing
Crystals, 11, 2021
7JLY
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BU of 7jly by Molmil
Crystal Structure of RNA Binding Protein PG1
Descriptor: ACETATE ION, CALCIUM ION, RNA-binding protein
Authors:Musayev, F.N, Scarsdale, J.N, Belvin, B.R, Lewis, J.P.
Deposit date:2020-07-30
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:High Resolution Structure of RNA Binding Protein PG1
To be published

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