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4BOI
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BU of 4boi by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes class A
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-20
Release date:2013-06-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (41 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4AQ5
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BU of 4aq5 by Molmil
Gating movement in acetylcholine receptor analysed by time-resolved electron cryo-microscopy (closed class)
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Unwin, N, Fujiyoshi, Y.
Deposit date:2012-04-12
Release date:2012-08-01
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Gating Movement of Acetylcholine Receptor Caught by Plunge-Freezing.
J.Mol.Biol., 422, 2012
4BOT
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BU of 4bot by Molmil
The structure and super-organization of acetylcholine receptor- rapsyn complexes class E
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-22
Release date:2013-06-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (42 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BON
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BU of 4bon by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes class B
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-21
Release date:2013-06-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (40 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BOO
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BU of 4boo by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes class C
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-21
Release date:2013-06-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (42 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BOR
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BU of 4bor by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes class D
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-22
Release date:2013-06-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (42 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BOG
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BU of 4bog by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes
Descriptor: Acetylcholine receptor beta subunit, Acetylcholine receptor delta subunit, Acetylcholine receptor gamma subunit, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-20
Release date:2013-06-26
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (50 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
8VRN
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BU of 8vrn by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus PPTQ
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-methylphenyl)-2-phenylquinazolin-4(3H)-one, ...
Authors:Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E.
Deposit date:2024-01-22
Release date:2024-06-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structural insights into GABA A receptor potentiation by Quaalude.
Nat Commun, 15, 2024
8VQY
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BU of 8vqy by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus methaqualone
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E.
Deposit date:2024-01-19
Release date:2024-06-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural insights into GABA A receptor potentiation by Quaalude.
Nat Commun, 15, 2024
6HUK
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BU of 6huk by Molmil
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with bicuculline and megabody Mb38.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-1,Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit beta-3, ...
Authors:Masiulis, S, Desai, R, Uchanski, T, Serna Martin, I, Laverty, D, Karia, D, Malinauskas, T, Jasenko, Z, Pardon, E, Kotecha, A, Steyaert, J, Miller, K.W, Aricescu, A.R.
Deposit date:2018-10-08
Release date:2019-01-02
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:GABAAreceptor signalling mechanisms revealed by structural pharmacology.
Nature, 565, 2019
8ZFK
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BU of 8zfk by Molmil
Caenorhabditis elegans ACR-23 in betaine and monepantel bound state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betaine receptor acr-23,Soluble cytochrome b562, ...
Authors:Chen, Q.F, Liu, F.L, Li, T.Y, Gong, H.H, Guo, F, Liu, S.
Deposit date:2024-05-08
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural basis of acetylcholine receptor like-23 (ACR-23) activation by anthelmintics monepantel and betaine
To Be Published
6HIN
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BU of 6hin by Molmil
Mouse serotonin 5-HT3 receptor, serotonin-bound, F conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ...
Authors:Polovinkin, L, Neumann, E, Schoehn, G, Nury, H.
Deposit date:2018-08-30
Release date:2018-11-07
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Conformational transitions of the serotonin 5-HT3receptor.
Nature, 563, 2018
6HIQ
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BU of 6hiq by Molmil
Mouse serotonin 5-HT3 receptor, serotonin-bound, I2 conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ...
Authors:Polovinkin, L, Neumann, E, Schoehn, G, Nury, H.
Deposit date:2018-08-30
Release date:2018-11-07
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Conformational transitions of the serotonin 5-HT3receptor.
Nature, 563, 2018
6HUG
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BU of 6hug by Molmil
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with picrotoxin and megabody Mb38.
Descriptor: (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-1, ...
Authors:Masiulis, S, Desai, R, Uchanski, T, Serna Martin, I, Laverty, D, Karia, D, Malinauskas, T, Jasenko, Z, Pardon, E, Kotecha, A, Steyaert, J, Miller, K.W, Aricescu, A.R.
Deposit date:2018-10-08
Release date:2019-01-02
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:GABAAreceptor signalling mechanisms revealed by structural pharmacology.
Nature, 565, 2019
6HUO
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BU of 6huo by Molmil
CryoEM structure of human full-length heteromeric alpha1beta3gamma2L GABA(A)R in complex with alprazolam (Xanax), GABA and megabody Mb38.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Masiulis, S, Desai, R, Uchanski, T, Serna Martin, I, Laverty, D, Karia, D, Malinauskas, T, Jasenko, Z, Pardon, E, Kotecha, A, Steyaert, J, Miller, K.W, Aricescu, A.R.
Deposit date:2018-10-09
Release date:2019-01-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:GABAAreceptor signalling mechanisms revealed by structural pharmacology.
Nature, 565, 2019
9AWK
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BU of 9awk by Molmil
Bovine fetal muscle nAChR resting state
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, H, Hibbs, R.E.
Deposit date:2024-03-05
Release date:2024-07-31
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.14 Å)
Cite:Structural switch in acetylcholine receptors in developing muscle.
Nature, 632, 2024
6HIO
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BU of 6hio by Molmil
Mouse serotonin 5-HT3 receptor, serotonin-bound, I1 conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ...
Authors:Polovinkin, L, Neumann, E, Schoehn, G, Nury, H.
Deposit date:2018-08-30
Release date:2018-11-07
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Conformational transitions of the serotonin 5-HT3receptor.
Nature, 563, 2018
8ZFL
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BU of 8zfl by Molmil
Caenorhabditis elegans ACR-23 in apo state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betaine receptor acr-23,Soluble cytochrome b562
Authors:Chen, Q.F, Liu, F.L, Li, T.Y, Gong, H.H, Guo, F, Liu, S.
Deposit date:2024-05-08
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural basis of acetylcholine receptor like-23 (ACR-23) activation by anthelmintics monepantel and betaine
To Be Published
8ZFM
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BU of 8zfm by Molmil
Caenorhabditis elegans ACR-23 in betaine bound state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betaine receptor acr-23,Soluble cytochrome b562, ...
Authors:Chen, Q.F, Liu, F.L, Li, T.Y, Gong, H.H, Guo, F, Liu, S.
Deposit date:2024-05-08
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural basis of acetylcholine receptor like-23 (ACR-23) activation by anthelmintics monepantel and betaine
To Be Published
9AVU
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BU of 9avu by Molmil
Bovine fetal muscle nAChR bound to ACh
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, ...
Authors:Li, H, Hibbs, R.E.
Deposit date:2024-03-05
Release date:2024-07-31
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Structural switch in acetylcholine receptors in developing muscle.
Nature, 632, 2024
9AVV
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BU of 9avv by Molmil
Bovine adult muscle nAChR resting state
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor subunit alpha, ...
Authors:Li, H, Hibbs, R.E.
Deposit date:2024-03-05
Release date:2024-07-31
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.09 Å)
Cite:Structural switch in acetylcholine receptors in developing muscle.
Nature, 632, 2024
6HIS
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BU of 6his by Molmil
Mouse serotonin 5-HT3 receptor, tropisetron-bound, T conformation
Descriptor: (3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ...
Authors:Polovinkin, L, Neumann, E, Schoehn, G, Nury, H.
Deposit date:2018-08-30
Release date:2018-11-07
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Conformational transitions of the serotonin 5-HT3receptor.
Nature, 563, 2018
9AWJ
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BU of 9awj by Molmil
Bovine adult muscle nAChR bound to ACh
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, ...
Authors:Li, H, Hibbs, R.E.
Deposit date:2024-03-05
Release date:2024-07-31
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Structural switch in acetylcholine receptors in developing muscle.
Nature, 632, 2024
6HUJ
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BU of 6huj by Molmil
CryoEM structure of human full-length heteromeric alpha1beta3gamma2L GABA(A)R in complex with picrotoxin, GABA and megabody Mb38.
Descriptor: (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Masiulis, S, Desai, R, Uchanski, T, Serna Martin, I, Laverty, D, Karia, D, Malinauskas, T, Jasenko, Z, Pardon, E, Kotecha, A, Steyaert, J, Miller, K.W, Aricescu, A.R.
Deposit date:2018-10-08
Release date:2019-01-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:GABAAreceptor signalling mechanisms revealed by structural pharmacology.
Nature, 565, 2019
6HUP
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BU of 6hup by Molmil
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with diazepam (Valium), GABA and megabody Mb38.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Masiulis, S, Desai, R, Uchanski, T, Serna Martin, I, Laverty, D, Karia, D, Malinauskas, T, Jasenko, Z, Pardon, E, Kotecha, A, Steyaert, J, Miller, K.W, Aricescu, A.R.
Deposit date:2018-10-09
Release date:2019-01-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:GABAAreceptor signalling mechanisms revealed by structural pharmacology.
Nature, 565, 2019

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