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3HIJ
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BU of 3hij by Molmil
Crystal structure of dihydrodipicolinate synthase from Bacillus anthracis in complex with its substrate, pyruvate
Descriptor: Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION
Authors:Voss, J.E, Scally, S.W, Dobson, R.C.J, Perugini, M.A.
Deposit date:2009-05-20
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax.
J.Biol.Chem., 285, 2010
5C55
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BU of 5c55 by Molmil
Crystal structure of the Y138F mutant of C.glutamicum N-acetylneuraminic acid lyase in complex with pyruvate
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Dihydrodipicolinate synthase/N-acetylneuraminate lyase, ...
Authors:Shen, Y, Zhou, J, Xie, J.
Deposit date:2015-06-19
Release date:2016-06-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the Y138F mutant of C.glutamicum N-acetylneuraminic acid lyase in complex with pyruvate
To Be Published
3B4U
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BU of 3b4u by Molmil
Crystal structure of dihydrodipicolinate synthase from Agrobacterium tumefaciens str. C58
Descriptor: Dihydrodipicolinate synthase, MAGNESIUM ION
Authors:Zhang, R, Xu, L, Gu, J, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-10-24
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The crystal structure of the dihydrodipicolinate synthase from Agrobacterium tumefaciens.
To be Published
4AHP
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BU of 4ahp by Molmil
Crystal Structure of Wild Type N-acetylneuraminic acid lyase from Staphylococcus aureus
Descriptor: CHLORIDE ION, N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A.
Deposit date:2012-02-06
Release date:2013-01-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
4AHO
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BU of 4aho by Molmil
Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165
Descriptor: CHLORIDE ION, N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A.
Deposit date:2012-02-06
Release date:2013-01-23
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
4AMA
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BU of 4ama by Molmil
Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165 in complex with pyruvate
Descriptor: N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A.
Deposit date:2012-03-08
Release date:2013-01-23
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into the recovery of aldolase activity in N-acetylneuraminic acid lyase by replacement of the catalytically active lysine with gamma-thialysine by using a chemical mutagenesis strategy.
Chembiochem, 14, 2013
8U91
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BU of 8u91 by Molmil
Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, Orthorhombic P form)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, N-acetylneuraminate lyase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-18
Release date:2023-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, Orthorhombic P form)
To be published
8U92
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BU of 8u92 by Molmil
Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound, Orthorhombic P form)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-18
Release date:2023-09-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound, Orthorhombic P form)
To be published
8U90
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BU of 8u90 by Molmil
Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, hexagonal form)
Descriptor: CHLORIDE ION, GLYCEROL, IODIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-18
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (Apo, hexagonal form)
To be published
8U93
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BU of 8u93 by Molmil
Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (PEG bound)
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-18
Release date:2023-09-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (PEG bound)
To be published
8U8W
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BU of 8u8w by Molmil
Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate and halides bound)
Descriptor: CHLORIDE ION, GLYCEROL, IODIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-18
Release date:2023-09-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate and halides bound)
To be published
2NUW
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BU of 2nuw by Molmil
2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius, native structure at 1.8 A resolution
Descriptor: 2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase, MAGNESIUM ION
Authors:van Eerde, A, Dijkstra, B.W.
Deposit date:2006-11-10
Release date:2007-04-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
Biochem.J., 403, 2007
2OJP
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BU of 2ojp by Molmil
The crystal structure of a dimeric mutant of Dihydrodipicolinate synthase from E.coli- DHDPS-L197Y
Descriptor: Dihydrodipicolinate synthase, GLYCEROL
Authors:Griffin, M.D.W, Dobson, R.C.J, Antonio, L, Perugini, M.A, Jameson, G.B, Gerrard, J.A.
Deposit date:2007-01-13
Release date:2008-01-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Evolution of quaternary structure in a homotetrameric enzyme.
J.Mol.Biol., 380, 2008
2NUY
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BU of 2nuy by Molmil
2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius in complex with pyruvate
Descriptor: 2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase, MAGNESIUM ION, PYRUVIC ACID
Authors:van Eerde, A, Dijkstra, B.W.
Deposit date:2006-11-10
Release date:2007-04-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
Biochem.J., 403, 2007
2NUX
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BU of 2nux by Molmil
2-keto-3-deoxygluconate aldolase from Sulfolobus acidocaldarius, native structure in p6522 at 2.5 A resolution
Descriptor: 2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase, MAGNESIUM ION
Authors:van Eerde, A, Dijkstra, B.W.
Deposit date:2006-11-10
Release date:2007-04-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
Biochem.J., 403, 2007
4AHQ
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BU of 4ahq by Molmil
Crystal Structure of N-acetylneuraminic acid lyase mutant K165C from Staphylococcus aureus
Descriptor: N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A.
Deposit date:2012-02-06
Release date:2013-01-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
8UR1
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BU of 8ur1 by Molmil
Crystal structure N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound halide free active site)
Descriptor: CHLORIDE ION, GLYCEROL, N-acetylneuraminate lyase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-10-25
Release date:2023-11-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate bound halide free active site)
To be published
4AH7
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BU of 4ah7 by Molmil
Structure of Wild Type Stapylococcus aureus N-acetylneuraminic acid lyase in complex with pyruvate
Descriptor: N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Poyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A.
Deposit date:2012-02-03
Release date:2013-01-23
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
2PCQ
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BU of 2pcq by Molmil
Crystal structure of putative dihydrodipicolinate synthase (TTHA0737) from Thermus Thermophilus HB8
Descriptor: GLYCEROL, POTASSIUM ION, Putative dihydrodipicolinate synthase
Authors:Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, Kitamura, Y, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-30
Release date:2007-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of putative dihydrodipicolinate synthase (TTHA0737) from Thermus Thermophilus HB8
To be Published
4BWL
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BU of 4bwl by Molmil
Structure of the Y137A mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate, N-acetyl-D-mannosamine and N- acetylneuraminic acid
Descriptor: 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid, N-ACETYLNEURAMINATE LYASE, ...
Authors:Campeotto, I, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A.
Deposit date:2013-07-03
Release date:2014-02-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, Qm/Mm Simulation and Mutagenesis.
Acs Chem.Biol., 9, 2014
2PUR
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BU of 2pur by Molmil
Structure of dihydrodipicolinate synthase mutant Thr44Ser at 1.7 A.
Descriptor: Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ...
Authors:Dobson, R.C.J, Jameson, G.B, Gerrard, J.A.
Deposit date:2007-05-09
Release date:2008-05-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis.
Biochimie, 91, 2009
4HNN
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BU of 4hnn by Molmil
Dihydrodipicolinate Synthase from the common grapevine with pyruvate and lysine
Descriptor: Dihydrodipicolinate synthase, LYSINE
Authors:Atkinson, S.C, Dobson, R.C.J, Perugini, M.A.
Deposit date:2012-10-19
Release date:2013-09-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.
Plant Mol.Biol., 81, 2013
4ICN
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BU of 4icn by Molmil
Dihydrodipicolinate synthase from shewanella benthica
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DIHYDRODIPICOLINATE SYNTHASE, ...
Authors:Wubben, J.M, Paxman, J.J, Dogovski, C, Parker, M.W, Perugini, M.A.
Deposit date:2012-12-10
Release date:2013-12-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cold enzymology offers insight into molecular evolution in quaternary structure
To be Published
4IMG
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BU of 4img by Molmil
Crystal Structure of Pasteurella multocida N-Acetyl-D-Neuraminic acid lyase K164 mutant complexed with N-Glycolylneuraminic acid
Descriptor: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, 3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-D-galacto-non-2-ulosonic acid, N-acetylneuraminate lyase
Authors:Fisher, A.J, Huynh, N.
Deposit date:2013-01-02
Release date:2013-11-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis for Substrate Specificity and Mechanism of N-Acetyl-d-neuraminic Acid Lyase from Pasteurella multocida.
Biochemistry, 52, 2013
4IME
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BU of 4ime by Molmil
Crystal Structure of Pasteurella multocida N-Acetyl-D-Neuraminic acid lyase K164A Mutant
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, N-acetylneuraminate lyase
Authors:Fisher, A.J, Huynh, N.
Deposit date:2013-01-02
Release date:2013-11-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Substrate Specificity and Mechanism of N-Acetyl-d-neuraminic Acid Lyase from Pasteurella multocida.
Biochemistry, 52, 2013

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