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2FVQ
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BU of 2fvq by Molmil
A Structural Study of the CA Dinucleotide Step in the Integrase Processing Site of Moloney Murine Leukemia Virus
Descriptor: 5'-D(*CP*TP*TP*TP*CP*AP*TP*TP*AP*AP*TP*GP*AP*AP*AP*G)-3', reverse transcriptase
Authors:Montano, S.P, Cote, M.L, Roth, M.J, Georgiadis, M.M.
Deposit date:2006-01-31
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
7Z0Z
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BU of 7z0z by Molmil
Abortive infection DNA polymerase AbiK from Lactococcus lactis, Y44F variant
Descriptor: AbiK
Authors:Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M.
Deposit date:2022-02-24
Release date:2022-09-07
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
5HHJ
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BU of 5hhj by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ...
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-01-11
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5HHK
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BU of 5hhk by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group (Se-MET)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ...
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-01-11
Release date:2016-05-04
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5IRG
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BU of 5irg by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P212121 space group
Descriptor: POTASSIUM ION, Retron-type reverse transcriptase
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-03-13
Release date:2016-05-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5IRF
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BU of 5irf by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P1 space group
Descriptor: POTASSIUM ION, Retron-type reverse transcriptase
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-03-13
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
6B1R
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BU of 6b1r by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
Descriptor: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(1WA))-3'), DNA (5'-D(P*(IGU)P*(IGU)P*(IGU)P*AP*TP*AP*AP*G)-3'), Reverse transcriptase
Authors:Singh, I, Georgiadis, M.M.
Deposit date:2017-09-18
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
6B1S
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BU of 6b1s by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
Descriptor: DNA (5'-D(*CP*TP*TP*AP*TP*AP*(CGY)P*(CGY)P*TP*TP*TP*AP*TP*AP*AP*G)-3'), Reverse transcriptase
Authors:Singh, I, Georgiadis, M.M.
Deposit date:2017-09-18
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
6B1Q
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BU of 6b1q by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
Descriptor: DNA (5'-D(*CP*TP*TP*AP*TP*(CJ1)P*(CJ1)P*(CJ1))-3'), DNA (5'-D(P*(1AP)P*(1AP)P*(1AP)P*AP*TP*AP*AP*G)-3'), Reverse transcriptase
Authors:Singh, I, Georgiadis, M.M.
Deposit date:2017-09-18
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
3FSI
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BU of 3fsi by Molmil
Crystal structure of a trypanocidal 4,4'-Bis(imidazolinylamino)diphenylamine bound to DNA
Descriptor: 5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', ACETATE ION, ...
Authors:Glass, L.S, Georgiadis, M.M, Goodwin, K.D.
Deposit date:2009-01-09
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA.
Biochemistry, 48, 2009
5VBS
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BU of 5vbs by Molmil
Structural basis for a six letter alphabet including GATCKX
Descriptor: DNA (5'-D(*CP*TP*TP*AP*TP*(DX)P*(DX)P*T)-3'), DNA (5'-D(P*AP*(93D)P*(93D)P*AP*TP*AP*AP*G)-3'), reverse transcriptase catalytic fragment
Authors:Singh, I, Georgiadis, M.M.
Deposit date:2017-03-30
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K).
ACS Synth Biol, 6, 2017
7UYO
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BU of 7uyo by Molmil
Crystal structure of B-form alien DNA 5'-CTTSSPBZPSZBBAAG in a host-guest complex with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase
Descriptor: DNA (5'-D(*CP*TP*TP*(JSP)P*(JSP)P*(1WA)P*(IGU)P*(1W5))-3'), DNA (5'-D(P*(1WA)P*(JSP)P*(1W5)P*(IGU)P*(IGU)P*AP*AP*G)-3'), reverse transcriptase
Authors:Georgiadis, M.M.
Deposit date:2022-05-06
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of 'ALternative Isoinformational ENgineered' DNA in B-form.
Philos.Trans.R.Soc.Lond.B Biol.Sci., 378, 2023
1I6J
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BU of 1i6j by Molmil
CRYSTAL STRUCTURE OF A PSEUDO-16-MER DNA WITH STACKED GUANINES AND TWO G-A MISPAIRS COMPLEXED WITH THE N-TERMINAL FRAGMENT OF MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE
Descriptor: 5'-D(*AP*CP*GP*GP*GP*AP*CP*GP*AP*C)-3', 5'-D(*GP*TP*CP*GP*TP*C)-3', REVERSE TRANSCRIPTASE
Authors:Cote, M.L, Georgiadis, M.M.
Deposit date:2001-03-02
Release date:2001-09-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a pseudo-16-mer DNA with stacked guanines and two G-A mispairs complexed with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase.
Acta Crystallogr.,Sect.D, 57, 2001
7K9Y
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BU of 7k9y by Molmil
GsI-IIC RT Template-Switching Complex (twinned)
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*CP*CP*AP*GP*GP*CP*AP*AP*C)-3'), MAGNESIUM ION, ...
Authors:Stamos, J.L, Lentzsch, A.M.
Deposit date:2020-09-29
Release date:2021-08-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for template switching by a group II intron-encoded non-LTR-retroelement reverse transcriptase.
J.Biol.Chem., 297, 2021
7O0H
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BU of 7o0h by Molmil
Structure of the foamy viral protease-reverse transcriptase dRH in complex with ds DNA.
Descriptor: DNA (5'-D(*AP*AP*CP*AP*GP*AP*GP*TP*GP*CP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), Pr125Pol
Authors:Nowak, E, Nowacka, M, Nowotny, M.
Deposit date:2021-03-26
Release date:2021-06-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase.
J.Virol., 95, 2021
8R0S
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BU of 8r0s by Molmil
Structure of reverse transcriptase from Cauliflower Mosaic Virus in complex with RNA/DNA hybrid
Descriptor: DNA (5'-D(*GP*CP*TP*AP*CP*GP*CP*AP*CP*TP*GP*CP*TP*GP*GP*A)-3'), Enzymatic polyprotein, RNA (5'-R(*GP*UP*CP*CP*AP*GP*CP*AP*GP*UP*GP*CP*GP*UP*AP*GP*C)-3')
Authors:Prabaharan, C, Figiel, M, Chamera, S, Szczepanowski, R, Nowak, E, Nowotny, M.
Deposit date:2023-10-31
Release date:2024-07-24
Last modified:2024-08-21
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and biochemical characterization of cauliflower mosaic virus reverse transcriptase.
J.Biol.Chem., 300, 2024
6ZDQ
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BU of 6zdq by Molmil
Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric RNA
Descriptor: RNA, Telomerase reverse transcriptase
Authors:Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G.
Deposit date:2020-06-15
Release date:2021-04-28
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡.
Nucleic Acids Res., 49, 2021
6ZDU
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BU of 6zdu by Molmil
Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric RNA
Descriptor: Chains: C,D, Telomerase reverse transcriptase
Authors:Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G.
Deposit date:2020-06-15
Release date:2021-04-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡.
Nucleic Acids Res., 49, 2021
8H2H
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BU of 8h2h by Molmil
Cryo-EM structure of a Group II Intron Complexed with its Reverse Transcriptase
Descriptor: Group II intron-encoded protein LtrA, LtrB, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3')
Authors:Liu, N, Dong, X.L, Qu, G.S, Wang, J, Wang, H.W, Belfort, M.
Deposit date:2022-10-06
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Functionalized graphene grids with various charges for single-particle cryo-EM.
Nat Commun, 13, 2022
7D1A
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BU of 7d1a by Molmil
cryo-EM structure of a group II intron RNP complexed with its reverse transcriptase
Descriptor: Group II intron-encoded protein LtrA, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3'), RNA (692-MER)
Authors:Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M.
Deposit date:2020-09-14
Release date:2020-10-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing.
Nucleic Acids Res., 48, 2020
7BG9
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BU of 7bg9 by Molmil
The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate
Descriptor: DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2A, Histone H2B, ...
Authors:Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K.
Deposit date:2021-01-06
Release date:2021-04-28
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of human telomerase holoenzyme with bound telomeric DNA.
Nature, 593, 2021
7D0F
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BU of 7d0f by Molmil
cryo-EM structure of a pre-catalytic group II intron RNP
Descriptor: Group II intron-encoded protein LtrA, RNA (738-MER)
Authors:Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M.
Deposit date:2020-09-10
Release date:2020-09-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing.
Nucleic Acids Res., 48, 2020
7D0G
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BU of 7d0g by Molmil
Cryo-EM structure of a pre-catalytic group II intron
Descriptor: Group II intron-encoded protein LtrA, RNA (714-MER)
Authors:Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M.
Deposit date:2020-09-10
Release date:2020-09-30
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing.
Nucleic Acids Res., 48, 2020
7Q5B
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BU of 7q5b by Molmil
Cryo-EM structure of Ty3 retrotransposon targeting a TFIIIB-bound tRNA gene
Descriptor: DNA (19-MER), DNA (31-MER), DNA (34-MER), ...
Authors:Abascal-Palacios, G, Jochem, L, Pla-Prats, C, Beuron, F, Vannini, A.
Deposit date:2021-11-03
Release date:2022-01-26
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes.
Nat Commun, 12, 2021
7QXA
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BU of 7qxa by Molmil
Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened)
Descriptor: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
Authors:Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
Deposit date:2022-01-26
Release date:2022-03-02
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022

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