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3JXJ
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BU of 3jxj by Molmil
Crystal structure of the chicken TRPV4 ankyrin repeat domain
Descriptor: PHOSPHATE ION, Vanilloid receptor-related osmotically activated channel protein
Authors:Phelps, C.B, Choo, S.S, Gaudet, R.
Deposit date:2009-09-19
Release date:2009-12-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C.
Nat.Genet., 42, 2010
3JXI
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BU of 3jxi by Molmil
Crystal structure of the chicken TRPV4 ankyrin repeat domain
Descriptor: Vanilloid receptor-related osmotically activated channel protein
Authors:Phelps, C.B, Wang, R.R, Gaudet, R.
Deposit date:2009-09-19
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C.
Nat.Genet., 42, 2010
7PTY
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BU of 7pty by Molmil
Delta-latroinsectotoxin dimer
Descriptor: Delta-latroinsectotoxin-Lt1a
Authors:Chen, M, Gatsogiannis, C.
Deposit date:2021-09-27
Release date:2021-12-08
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (4.63 Å)
Cite:Molecular architecture of black widow spider neurotoxins.
Nat Commun, 12, 2021
5H2C
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BU of 5h2c by Molmil
Crystal structure of Saccharomyces cerevisiae Osh1 ANK - Nvj1
Descriptor: Nucleus-vacuole junction protein 1, Oxysterol-binding protein homolog 1
Authors:Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S.
Deposit date:2016-10-14
Release date:2017-05-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.508 Å)
Cite:Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
5GP7
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BU of 5gp7 by Molmil
Structural basis for the binding between Tankyrase-1 and USP25
Descriptor: GLYCEROL, Tankyrase-1, Ubiquitin carboxyl-terminal hydrolase 25
Authors:Liu, J, Xu, D, Fu, T, Pan, L.
Deposit date:2016-08-01
Release date:2017-07-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:USP25 regulates Wnt signaling by controlling the stability of tankyrases
Genes Dev., 31, 2017
5YBJ
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BU of 5ybj by Molmil
Structure of apo KANK1 ankyrin domain
Descriptor: GLYCEROL, KN motif and ankyrin repeat domain-containing protein 1
Authors:Guo, Q, Liao, S, Min, J, Xu, C, Structural Genomics Consortium (SGC)
Deposit date:2017-09-05
Release date:2017-12-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.341 Å)
Cite:Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins.
J. Biol. Chem., 293, 2018
5Y4F
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BU of 5y4f by Molmil
Crystal Structure of AnkB Ankyrin Repeats R13-24 in complex with autoinhibition segment AI-c
Descriptor: ACETATE ION, Ankyrin-2, CALCIUM ION
Authors:Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M.
Deposit date:2017-08-03
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5H28
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BU of 5h28 by Molmil
Crystal structure of Osh1 ANK domain from Saccharomyces cerevisia
Descriptor: Oxysterol-binding protein homolog 1
Authors:Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S.
Deposit date:2016-10-14
Release date:2017-05-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
5H2A
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BU of 5h2a by Molmil
Crystal structure of Osh1 ANK domain from Kluyveromyces lactis
Descriptor: KLLA0C04147p
Authors:Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S.
Deposit date:2016-10-14
Release date:2017-05-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
5YBU
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BU of 5ybu by Molmil
Structure of the KANK1 ankyrin domain in complex with KIF21A peptide
Descriptor: KN motif and ankyrin repeat domain-containing protein 1, Kinesin-like protein KIF21A
Authors:Guo, Q, Liao, S, Min, J, Xu, C, Structural Genomics Consortium (SGC)
Deposit date:2017-09-05
Release date:2017-12-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins.
J. Biol. Chem., 293, 2018
3UI2
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BU of 3ui2 by Molmil
Crystal structure of the cpSRP54 tail bound to cpSRP43
Descriptor: Signal recognition particle 43 kDa protein, chloroplastic, Signal recognition particle 54 kDa protein
Authors:Holdermann, I, Wild, K, Sinning, I.
Deposit date:2011-11-04
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.178 Å)
Cite:Chromodomains read the arginine code of post-translational targeting.
Nat.Struct.Mol.Biol., 19, 2012
3UXG
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BU of 3uxg by Molmil
Crystal structure of RFXANK
Descriptor: DNA-binding protein RFXANK, Histone deacetylase 4, UNKNOWN ATOM OR ION
Authors:Tempel, W, Chao, X, Bian, C, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-05
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
5Y4E
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BU of 5y4e by Molmil
Crystal Structure of AnkB Ankyrin Repeats R8-14 in complex with autoinhibition segment AI-b
Descriptor: Ankyrin-2,Ankyrin-2, GLYCEROL, SULFATE ION
Authors:Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M.
Deposit date:2017-08-03
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.341 Å)
Cite:Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5Y4D
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BU of 5y4d by Molmil
Crystal Structure of AnkB Ankyrin Repeats in Complex with AnkR/AnkB Chimeric Autoinhibition Segment
Descriptor: Ankyrin-1,Ankyrin-2,Ankyrin-2, SULFATE ION
Authors:Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M.
Deposit date:2017-08-03
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5JHQ
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BU of 5jhq by Molmil
ARCs 1-3 of human Tankyrase-1 bound to a peptide derived from IRAP
Descriptor: Peptide derived from insulin-responsive aminopeptidase (IRAP), Tankyrase-1
Authors:Eisemann, T, Pascal, J.M.
Deposit date:2016-04-21
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Tankyrase-1 Ankyrin Repeats Form an Adaptable Binding Platform for Targets of ADP-Ribose Modification.
Structure, 24, 2016
3V30
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BU of 3v30 by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human RFXANK
Descriptor: DNA-binding protein RFX5, DNA-binding protein RFXANK
Authors:Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
6TLH
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BU of 6tlh by Molmil
Crystal structure of mouse KANK3 ankyrin repeats
Descriptor: FORMIC ACID, GLYCEROL, KN motif and ankyrin repeat domain-containing protein 3
Authors:Khan, R, Singh, A.K, Goult, B.T.
Deposit date:2019-12-02
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of mouse KANK3 ankyrin repeats
To be published
4LG6
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BU of 4lg6 by Molmil
Crystal structure of ANKRA2-CCDC8 complex
Descriptor: Ankyrin repeat family A protein 2, Coiled-coil domain-containing protein 8, UNKNOWN ATOM OR ION
Authors:Xu, C, Bian, C, Tempel, W, Mackenzie, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-06-27
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ankyrin Repeats of ANKRA2 Recognize a PxLPxL Motif on the 3M Syndrome Protein CCDC8.
Structure, 23, 2015
1D9S
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BU of 1d9s by Molmil
TUMOR SUPPRESSOR P15(INK4B) STRUCTURE BY COMPARATIVE MODELING AND NMR DATA
Descriptor: CYCLIN-DEPENDENT KINASE 4 INHIBITOR B
Authors:Yuan, C, Ji, L, Selby, T.L, Byeon, I.J.L, Tsai, M.D.
Deposit date:1999-10-29
Release date:2000-07-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Tumor suppressor INK4: comparisons of conformational properties between p16(INK4A) and p18(INK4C).
J.Mol.Biol., 294, 1999
5VKQ
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BU of 5vkq by Molmil
Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, No mechanoreceptor potential C isoform L
Authors:Jin, P, Bulkley, D, Guo, Y, Zhang, W, Guo, Z, Huynh, W, Wu, S, Meltzer, S, Chen, T, Jan, L.Y, Jan, Y.-N, Cheng, Y.
Deposit date:2017-04-22
Release date:2017-06-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.
Nature, 547, 2017
2QC9
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BU of 2qc9 by Molmil
Mouse Notch 1 Ankyrin Repeat Intracellular Domain
Descriptor: Notch 1 protein
Authors:McDonough, M.A, Schofield, C.J.
Deposit date:2007-06-19
Release date:2008-03-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.
J.Biol.Chem., 282, 2007
3NBN
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BU of 3nbn by Molmil
Crystal structure of a dimer of Notch Transcription Complex trimers on HES1 DNA
Descriptor: DNA, HES1 promoter, Mastermind-like protein 1, ...
Authors:Arnett, K.L, Blacklow, S.C.
Deposit date:2010-06-03
Release date:2010-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes.
Nat.Struct.Mol.Biol., 17, 2010
6X2J
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BU of 6x2j by Molmil
Structure of human TRPA1 in complex with agonist GNE551
Descriptor: 5-amino-1-[(4-bromo-2-fluorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-1H-1,2,3-triazole-4-carboxamide, Transient receptor potential cation channel subfamily A member 1
Authors:Rohou, A, Rouge, L, Chen, H.
Deposit date:2020-05-20
Release date:2020-11-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel.
Neuron, 109, 2021
6YSN
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BU of 6ysn by Molmil
Human TRPC5 in complex with Pico145 (HC-608)
Descriptor: 7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)-8-[3-(trifluoromethyloxy)phenoxy]purine-2,6-dione, Maltose/maltodextrin-binding periplasmic protein,Short transient receptor potential channel 5
Authors:Wright, D.J, Johnson, R.M, Muench, S.P, Bon, R.S.
Deposit date:2020-04-22
Release date:2020-12-02
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site.
Commun Biol, 3, 2020
6WJ5
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BU of 6wj5 by Molmil
Structure of human TRPA1 in complex with inhibitor GDC-0334
Descriptor: (4R,5S)-4-fluoro-1-[(4-fluorophenyl)sulfonyl]-5-methyl-N-({5-(trifluoromethyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]pyridin-4-yl}methyl)-L-prolinamide, Transient receptor potential cation channel subfamily A member 1
Authors:Rohou, A, Rouge, L, Arthur, C.P, Volgraf, M, Chen, H.
Deposit date:2020-04-11
Release date:2021-02-17
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment.
J.Exp.Med., 218, 2021

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