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6C3O
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Cryo-EM structure of human KATP bound to ATP and ADP in quatrefoil form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Lee, K.P.K, Chen, J, MacKinnon, R.
Deposit date:2018-01-10
Release date:2018-01-31
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular structure of human KATP in complex with ATP and ADP
Elife, 6, 2017
6BPP
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E. coli MsbA in complex with LPS and inhibitor G092
Descriptor: (2E)-3-{6-[(1S)-1-(3-amino-2,6-dichlorophenyl)ethoxy]-4-cyclopropylquinolin-3-yl}prop-2-enoic acid, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 3-HYDROXY-TETRADECANOIC ACID, ...
Authors:Ho, H, Koth, C.M, Payandeh, J.
Deposit date:2017-11-24
Release date:2018-05-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural basis for dual-mode inhibition of the ABC transporter MsbA.
Nature, 557, 2018
3G5U
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Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Descriptor: MERCURY (II) ION, Multidrug resistance protein 1a
Authors:Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
3G61
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Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Descriptor: (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a
Authors:Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.35 Å)
Cite:Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
4AYT
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BU of 4ayt by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10 MITOCHONDRIAL, CARDIOLIPIN, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
3J16
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BU of 3j16 by Molmil
Models of ribosome-bound Dom34p and Rli1p and their ribosomal binding partners
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S24-A, ...
Authors:Becker, T, Franckenberg, S, Wickles, S, Shoemaker, C.J, Anger, A.M, Armache, J.-P, Sieber, H, Ungewickell, C, Berninghausen, O, Daberkow, I, Karcher, A, Thomm, M, Hopfner, K.-P, Green, R, Beckmann, R.
Deposit date:2011-12-12
Release date:2012-02-22
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural basis of highly conserved ribosome recycling in eukaryotes and archaea.
Nature, 482, 2012
4JBW
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Crystal structure of E. coli maltose transporter MalFGK2 in complex with its regulatory protein EIIAglc
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Glucose-specific phosphotransferase enzyme IIA component, Maltose transport system permease protein MalF, ...
Authors:Chen, S, Oldham, M.L, Davidson, A.L, Chen, J.
Deposit date:2013-02-20
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.913 Å)
Cite:Carbon catabolite repression of the maltose transporter revealed by X-ray crystallography.
Nature, 499, 2013
6BHU
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BU of 6bhu by Molmil
Cryo-EM structure of ATP-bound, outward-facing bovine multidrug resistance protein 1 (MRP1)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, MAGNESIUM ION, ...
Authors:Johnson, Z.L, Chen, J.
Deposit date:2017-10-31
Release date:2017-12-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1.
Cell, 172, 2018
6D3S
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BU of 6d3s by Molmil
Thermostabilized phosphorylated chicken CFTR
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator
Authors:Fay, J.F, Riordan, J.R, Chen, Z.J.
Deposit date:2018-04-16
Release date:2018-10-17
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel.
Biochemistry, 57, 2018
4KI0
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Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to maltohexaose
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, ABC transporter related protein, Binding-protein-dependent transport systems inner membrane component, ...
Authors:Oldham, M.L, Chen, S, Chen, J.
Deposit date:2013-05-01
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural basis for substrate specificity in the Escherichia coli maltose transport system.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSC
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BU of 4ksc by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
6C3P
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BU of 6c3p by Molmil
Cryo-EM structure of human KATP bound to ATP and ADP in propeller form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Lee, K.P.K, Chen, J, MacKinnon, R.
Deposit date:2018-01-10
Release date:2018-01-24
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Molecular structure of human KATP in complex with ATP and ADP.
Elife, 6, 2017
6C0V
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Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance protein 1
Authors:Kim, Y.J, Chen, J.
Deposit date:2018-01-02
Release date:2018-01-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation.
Science, 359, 2018
4AYW
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BU of 4ayw by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM)
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSD
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BU of 4ksd by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A, R2 protein
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (4.1001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSB
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BU of 4ksb by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
3JAH
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BU of 3jah by Molmil
Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V.
Deposit date:2015-06-10
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
3ZDQ
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BU of 3zdq by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (NUCLEOTIDE-FREE FORM)
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL, CARDIOLIPIN, ...
Authors:Pike, A.C.W, Shintre, C.A, Krojer, T, von Delft, F, Vollmar, M, Mukhopadhyay, S, Burgess-Brown, N, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-11-30
Release date:2013-01-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
3B5X
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Crystal Structure of MsbA from Vibrio cholerae
Descriptor: Lipid A export ATP-binding/permease protein msbA
Authors:Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4AYX
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BU of 4ayx by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (ROD FORM B)
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, CARDIOLIPIN, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4A82
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Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966.
Descriptor: CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
Authors:Rosenberg, M.F, ORyan, L.P, Hughes, G, Zhao, Z, Aleksandrov, L.A, Riordan, J.R, Ford, R.C.
Deposit date:2011-11-18
Release date:2012-01-11
Last modified:2024-05-08
Method:ELECTRON CRYSTALLOGRAPHY (9 Å)
Cite:The Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):3D Structure and Localisation of a Channel Gate.
J.Biol.Chem., 286, 2011
3JAG
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Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V.
Deposit date:2015-06-10
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
3B5Z
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BU of 3b5z by Molmil
Crystal Structure of MsbA from Salmonella typhimurium with ADP Vanadate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lipid A export ATP-binding/permease protein msbA, VANADATE ION
Authors:Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3J5S
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EttA binds to ribosome exit site and regulates translation by restricting ribosome and tRNA dynamics
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S7, ...
Authors:Hashem, Y.
Deposit date:2013-11-15
Release date:2014-01-08
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics.
Nat.Struct.Mol.Biol., 21, 2014
3B5W
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Crystal Structure of Eschericia coli MsbA
Descriptor: Lipid A export ATP-binding/permease protein msbA
Authors:Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (5.3 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007

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