6C0V
Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation
Summary for 6C0V
Entry DOI | 10.2210/pdb6c0v/pdb |
EMDB information | 7325 |
Descriptor | Multidrug resistance protein 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION (3 entities in total) |
Functional Keywords | abc transporter; abcb1; p-glycoprotein; cryo-em; multidrug resistance, structural genomics, psi-2, protein structure initiative, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 143723.89 |
Authors | |
Primary citation | Kim, Y.,Chen, J. Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation. Science, 359:915-919, 2018 Cited by PubMed: 29371429DOI: 10.1126/science.aar7389 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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