8Q3C

Structure of Selenomonas ruminantium lactate dehydrogenase I85R mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
H	0003824	molecular_function	catalytic activity
H	0004459	molecular_function	L-lactate dehydrogenase activity
H	0005737	cellular_component	cytoplasm
H	0006089	biological_process	lactate metabolic process
H	0006090	biological_process	pyruvate metabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
H	0019752	biological_process	carboxylic acid metabolic process
N	0003824	molecular_function	catalytic activity
N	0004459	molecular_function	L-lactate dehydrogenase activity
N	0005737	cellular_component	cytoplasm
N	0006089	biological_process	lactate metabolic process
N	0006090	biological_process	pyruvate metabolic process
N	0016491	molecular_function	oxidoreductase activity
N	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
N	0019752	biological_process	carboxylic acid metabolic process
U	0003824	molecular_function	catalytic activity
U	0004459	molecular_function	L-lactate dehydrogenase activity
U	0005737	cellular_component	cytoplasm
U	0006089	biological_process	lactate metabolic process
U	0006090	biological_process	pyruvate metabolic process
U	0016491	molecular_function	oxidoreductase activity
U	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
U	0019752	biological_process	carboxylic acid metabolic process
a	0003824	molecular_function	catalytic activity
a	0004459	molecular_function	L-lactate dehydrogenase activity
a	0005737	cellular_component	cytoplasm
a	0006089	biological_process	lactate metabolic process
a	0006090	biological_process	pyruvate metabolic process
a	0016491	molecular_function	oxidoreductase activity
a	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
a	0019752	biological_process	carboxylic acid metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
U	HIS180
N	HIS180
a	HIS180

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
U	SER13
U	ARG93
U	ASN125
U	ARG156
U	THR234
N	SER13
N	ARG93
N	ASN125
N	ARG156
N	THR234
a	SER13
a	ARG93
a	ASN125
a	ARG156
a	THR234

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000250

Chain	Residue	Details
U	TYR225
N	TYR225
a	TYR225

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